Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Daniela Anni"'
Autor:
Debarpan Guhathakurta, Aneta Petrušková, Enes Yağız Akdaş, Bartomeu Perelló-Amorós, Renato Frischknecht, Daniela Anni, Eva-Maria Weiss, Martin Walter, Anna Fejtová
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Ketamine is clinically used fast-acting antidepressant. Its metabolite hydroxynorketamine (HNK) shows a robust antidepressant effect in animal studies. It is unclear, how these chemically distinct compounds converge on similar neuronal effec
Externí odkaz:
https://doaj.org/article/66faa68a7b524b26b3fbcd9a4bf739d5
Autor:
Damiano Marastoni, Matteo Foschi, Chiara Eccher, Francesco Crescenzo, Valentina Mazziotti, Agnese Tamanti, Albulena Bajrami, Valentina Camera, Stefano Ziccardi, Maddalena Guandalini, Francesca Bosello, Daniela Anni, Federica Virla, Ermanna Turano, Michele Romoli, Raffaella Mariotti, Francesca Benedetta Pizzini, Bruno Bonetti, Massimiliano Calabrese
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCladribine has been introduced as a high-efficacy drug for treating relapsing-remitting multiple sclerosis (RRMS). Initial cohort studies showed early disease activity in the first year after drug initiation. Biomarkers that can predict ear
Externí odkaz:
https://doaj.org/article/9d9749d94e1345dbaab41d85453fce9a
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 588 (2022)
Early stroke therapeutic approaches rely on limited options, further characterized by a narrow therapeutic time window. In this context, the application of transcranial direct current stimulation (tDCS) in the acute phases after brain ischemia is eme
Externí odkaz:
https://doaj.org/article/39cb90616f8a4bc78d56867385eaf6b2
Autor:
Stefanie Zeitler, Fabian Schumacher, Juliana Monti, Daniela Anni, Debarpan Guhathakurta, Burkhard Kleuser, Kristina Friedland, Anna Fejtová, Johannes Kornhuber, Cosima Rhein
Publikováno v:
Cells, Vol 9, Iss 11, p 2502 (2020)
The acid sphingomyelinase (ASM)/ceramide system exhibits a crucial role in the pathology of major depressive disorder (MDD). ASM hydrolyzes the abundant membrane lipid sphingomyelin to ceramide that regulates the clustering of membrane proteins via m
Externí odkaz:
https://doaj.org/article/170c5c9bba314209a53ca85cf37b586b
Autor:
Vesna Lazarevic, Sandra Fieńko, Maria Andres-Alonso, Daniela Anni, Daniela Ivanova, Carolina Montenegro-Venegas, Eckart D. Gundelfinger, Michael A. Cousin, Anna Fejtova
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Despite the central role of amyloid β (Aβ) peptide in the etiopathogenesis of Alzheimer’s disease (AD), its physiological function in healthy brain is still debated. It is well established that elevated levels of Aβ induce synaptic depression an
Externí odkaz:
https://doaj.org/article/e4dc721102d84b10975c005a9b87b42b
Autor:
Joshua D. Bernstock, Cory M. Willis, Monica Emili Garcia-Segura, Edoardo Gaude, Daniela Anni, Yan-ja Lee, Luke W. Thomas, Alva Casey, Nunzio Vicario, Tommaso Leonardi, Alexandra M. Nicaise, Florian A. Gessler, Saef Izzy, Mario R. Buffelli, Jakob Seidlitz, Shriya Srinivasan, Michael P. Murphy, Margaret Ashcroft, Marco Cambiaghi, John M. Hallenbeck, Luca Peruzzotti-Jametti
Publikováno v:
bioRxiv
Ischemic stroke results in a loss of tissue homeostasis and integrity, the underlying pathobiology of which stems primarily from the depletion of cellular energy stores and perturbation of available metabolites1. Hibernation in thirteen-lined ground
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0929172e06840e2e80946326d23af9a7
https://europepmc.org/articles/PMC10187245/
https://europepmc.org/articles/PMC10187245/
The association between Alzheimer’s disease (AD) and type 2 diabetes mellitus (T2DM) has been extensively demonstrated, but despite this, the pathophysiological mechanisms underlying it are still unknown. In previous work, we discovered a central r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7732c0d971bbec968a4ad9ae9fa0fc35
https://hdl.handle.net/11562/1087733
https://hdl.handle.net/11562/1087733
Autor:
Debarpan Guhathakurta, Anna Fejtova, Tobias Huth, Julia Klueva, Stefanie Zeitler, Eva-Maria Weiss, Maria Andres-Alonso, Yagiz Enes Akdas, Daniela Anni
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and molecular life sciences, 78(11):4973-4992
Cellular and molecular life sciences, 78(11):4973-4992
Amyloid beta (Aβ) is linked to the pathology of Alzheimer’s disease (AD). At physiological concentrations, Aβ was proposed to enhance neuroplasticity and memory formation by increasing the neurotransmitter release from presynapse. However, the ex
Autor:
Renato Frischknecht, Daniela Anni, Sandra Fienko, Anna Fejtova, Eneko Pina-Fernández, Carolina Montenegro-Venegas
Publikováno v:
Cellular and molecular life sciences, 78(4):1545-1563
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences
Abstract Proteasomes are protein complexes that mediate controlled degradation of damaged or unneeded cellular proteins. In neurons, proteasome regulates synaptic function and its dysfunction has been linked to neurodegeneration and neuronal cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7065a14dbaa8004e79b254a80fee47b5
https://opus4.kobv.de/opus4-fau/files/22435/s00018-020-03590-z.pdf
https://opus4.kobv.de/opus4-fau/files/22435/s00018-020-03590-z.pdf
Autor:
Wout De Wispelaere, Daniela Annibali, Sandra Tuyaerts, Julie Messiaen, Asier Antoranz, Gautam Shankar, Nikolina Dubroja, Alejandro Herreros‐Pomares, Regina E. M. Baiden‐Amissah, Marie‐Pauline Orban, Marcello Delfini, Emanuele Berardi, Thomas Van Brussel, Rogier Schepers, Gino Philips, Bram Boeckx, Maria Francesca Baietti, Luigi Congedo, Kiave Yune HoWangYin, Emilie Bayon, Anne‐Sophie Van Rompuy, Eleonora Leucci, Sebastien P. Tabruyn, Francesca Bosisio, Massimiliano Mazzone, Diether Lambrechts, Frédéric Amant
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Background Uterine leiomyosarcomas (uLMS) are aggressive tumours with poor prognosis and limited treatment options. Although immune checkpoint blockade (ICB) has proven effective in some ‘challenging‐to‐treat’ cancers, clinical trial
Externí odkaz:
https://doaj.org/article/96c1f251d0ff4741b236139055f4119b