Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Daniela Alfano"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease urokinase (uPA), converting plasminogen into plasmin, a broad spectrum pr
Externí odkaz:
https://doaj.org/article/3e9ae378f3f64a3f8eac86cc92ed4834
Autor:
Anna Gorrasi, Anna Li Santi, Giuseppina Amodio, Daniela Alfano, Paolo Remondelli, Nunzia Montuori, Pia Ragno
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86352 (2014)
The receptor (uPAR) of the urokinase-type plasminogen activator (uPA) is crucial in cell migration since it concentrates uPA proteolytic activity at the cell surface, binds vitronectin and associates to integrins. uPAR cross-talk with receptors for t
Externí odkaz:
https://doaj.org/article/87c6a1bf23ed4cb1b4d4e25164f453fc
Autor:
Maria Sepe, Luisa Festa, Fabio Tolino, Luca Bellucci, Luca Sisto, Daniela Alfano, Pia Ragno, Viola Calabrò, Vittorio de Franciscis, Girolama La Mantia, Alessandra Pollice
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e22800 (2011)
TBP-1 /Tat-Binding Protein 1 (also named Rpt-5, S6a or PSMC3) is a multifunctional protein, originally identified as a regulator of HIV-1-Tat mediated transcription. It is an AAA-ATPase component of the 19S regulative subunit of the proteasome and, a
Externí odkaz:
https://doaj.org/article/c3eb5586f07d48f78db76e4bc3b59fcf
Autor:
Marchesa Bilio, Cinzia Caprio, Gennaro Ilardi, Daniela Alfano, Stefania Staibano, Antonio Baldini, Federica Feo, Rosa Ferrentino, Daniela Russo, Silvia Varricchio, Caterina Missero
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 607 (2020)
International journal of molecular sciences (Online) 21 (2020). doi:10.3390/ijms21020607
info:cnr-pdr/source/autori:Caprio C.; Varricchio S.; Bilio M.; Feo F.; Ferrentino R.; Russo D.; Staibano S.; Alfano D.; Missero C.; Ilardi G.; Baldini A./titolo:Tbx1 and basal cell carcinoma: Expression and interactions with gli2 and dvl2 signaling/doi:10.3390%2Fijms21020607/rivista:International journal of molecular sciences (Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:21
International Journal of Molecular Sciences
Volume 21
Issue 2
International journal of molecular sciences (Online) 21 (2020). doi:10.3390/ijms21020607
info:cnr-pdr/source/autori:Caprio C.; Varricchio S.; Bilio M.; Feo F.; Ferrentino R.; Russo D.; Staibano S.; Alfano D.; Missero C.; Ilardi G.; Baldini A./titolo:Tbx1 and basal cell carcinoma: Expression and interactions with gli2 and dvl2 signaling/doi:10.3390%2Fijms21020607/rivista:International journal of molecular sciences (Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:21
International Journal of Molecular Sciences
Volume 21
Issue 2
Early events of basal cell carcinoma (BCC) tumorigenesis are triggered by inappropriate activation of SHH signaling, via the loss of Patched1 (Ptch1) or by activating mutations of Smoothened (Smo). TBX1 is a key regulator of pharyngeal development, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0ad998bc9733f64b8e5e43a99fc76a
https://www.mdpi.com/1422-0067/21/2/607
https://www.mdpi.com/1422-0067/21/2/607
Autor:
Cinzia, Caprio, Silvia, Varricchio, Marchesa, Bilio, Federica, Feo, Rosa, Ferrentino, Daniela, Russo, Stefania, Staibano, Daniela, Alfano, Caterina, Missero, Gennaro, Ilardi, Antonio, Baldini
Publikováno v:
International Journal of Molecular Sciences
Early events of basal cell carcinoma (BCC) tumorigenesis are triggered by inappropriate activation of SHH signaling, via the loss of Patched1 (Ptch1) or by activating mutations of Smoothened (Smo). TBX1 is a key regulator of pharyngeal development, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fe044c59362626429d0b8f359733a99
https://pubmed.ncbi.nlm.nih.gov/31963474
https://pubmed.ncbi.nlm.nih.gov/31963474
Autor:
Claudio Cortes, Marchesa Bilio, Robert G. Kelly, Antonio Baldini, Alessandra Altomonte, Daniela Alfano
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2019, 28 (14), pp.2295-2308. ⟨10.1093/hmg/ddz058⟩
Human molecular genetics
28 (2019): 2295–2308. doi:10.1093/hmg/ddz058
info:cnr-pdr/source/autori:Alfano D.; Altomonte A.; Cortes C.; Bilio M.; Kelly R.G.; Baldini A./titolo:Tbx1 regulates extracellular matrix-cell interactions in the second heart field/doi:10.1093%2Fhmg%2Fddz058/rivista:Human molecular genetics (Print)/anno:2019/pagina_da:2295/pagina_a:2308/intervallo_pagine:2295–2308/volume:28
Human Molecular Genetics, 2019, 28 (14), pp.2295-2308. ⟨10.1093/hmg/ddz058⟩
Human Molecular Genetics, Oxford University Press (OUP), 2019, 28 (14), pp.2295-2308. ⟨10.1093/hmg/ddz058⟩
Human molecular genetics
28 (2019): 2295–2308. doi:10.1093/hmg/ddz058
info:cnr-pdr/source/autori:Alfano D.; Altomonte A.; Cortes C.; Bilio M.; Kelly R.G.; Baldini A./titolo:Tbx1 regulates extracellular matrix-cell interactions in the second heart field/doi:10.1093%2Fhmg%2Fddz058/rivista:Human molecular genetics (Print)/anno:2019/pagina_da:2295/pagina_a:2308/intervallo_pagine:2295–2308/volume:28
Human Molecular Genetics, 2019, 28 (14), pp.2295-2308. ⟨10.1093/hmg/ddz058⟩
SUMMARYTbx1,the major candidate gene for DiGeorge or 22q11.2 deletion syndrome, is required for efficient incorporation of cardiac progenitors (CPs) of the second heart field (SHF) into the heart. However, the mechanisms by which TBX1 regulates this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d957ac453d78c31401fad903cbab1e7
https://hal.archives-ouvertes.fr/hal-02436616
https://hal.archives-ouvertes.fr/hal-02436616
Autor:
Emilia Caputo, Daniela Alfano, Valeria Vasta, Salvatore Travali, Eduardo J. Patriarca, Anna Valentino, Ernesta Cavalcanti, Annalisa Fico
Publikováno v:
Cancer biology & therapy (Online) (2015): 1–12. doi:10.1080/15384047.2015.1030546
info:cnr-pdr/source/autori:Fico A, Alfano D, Valentino A, Vasta V, Cavalcanti E, Travali S, Patriarca EJ, Caputo E./titolo:c-Myc Modulation: a Key Role in Melanoma Drug Response/doi:10.1080%2F15384047.2015.1030546/rivista:Cancer biology & therapy (Online)/anno:2015/pagina_da:1/pagina_a:12/intervallo_pagine:1–12/volume
info:cnr-pdr/source/autori:Fico A, Alfano D, Valentino A, Vasta V, Cavalcanti E, Travali S, Patriarca EJ, Caputo E./titolo:c-Myc Modulation: a Key Role in Melanoma Drug Response/doi:10.1080%2F15384047.2015.1030546/rivista:Cancer biology & therapy (Online)/anno:2015/pagina_da:1/pagina_a:12/intervallo_pagine:1–12/volume
Understanding molecular mechanisms involved in melanoma resistance to drugs is a big challenge. Experimental evidences suggested a correlation between mutational status in B-RAF and melanoma cell susceptibility to drugs, such as paclitaxel, doxorubic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7218385f05c97efcdd3d0368e0b5a4d
https://doi.org/10.1080/15384047.2015.1030546
https://doi.org/10.1080/15384047.2015.1030546
Autor:
Vincenzo Cosimato, Nunzia Montuori, Loredana Rinaldi, Vincenza Elena Anna Rea, Daniela Alfano, Pia Ragno
Publikováno v:
Thrombosis and Haemostasis. 109:309-318
SummaryThe expression of the urokinase-type plasminogen activator (uPA) and its receptor (uPAR) can be regulated by several hormones, cytokines, and tumour promoters. uPAR is a glycosyl-phosphatidyl inositol (GPI)- linked cell-surface protein; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e072669ccff25da19b8abbf1fc6a61c
https://doi.org/10.1160/th12-08-0546
https://doi.org/10.1160/th12-08-0546
Autor:
Daniela Alfano, Pietro Formisano, Ada Pesapane, Nunzia Montuori, Raffaella Giusto, Pia Ragno, Francesco Beguinot, Vincenza Elena Anna Rea, Anna Teresa Alberobello, Guido Rossi, Francesca Rossi
Publikováno v:
Journal of Cellular and Molecular Medicine
Phosphoprotein enriched in diabetes/phosphoprotein enriched in astrocytes-15 kD (PED/PEA-15) is an anti-apoptotic protein whose expression is increased in several human cancers. In addition to apoptosis, PED/PEA-15 is involved in the regulation of ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5eedd5cfee83c452a1b8824d898c00
https://doi.org/10.1111/j.1582-4934.2011.01411.x
https://doi.org/10.1111/j.1582-4934.2011.01411.x
Autor:
Julian Downward, Almut Schulze, Ingram Iaccarino, Giuseppina Votta, Maria Patrizia Stoppelli, Mario Caputi, Daniela Alfano
Publikováno v:
Molecular and cellular biology
30 (2010): 1838–1851. doi:10.1128/MCB.01442-09
info:cnr-pdr/source/autori:Alfano D.; Votta G.; Schulze A.; Downward J.; Caputi M.; Stoppelli M.P.; Iaccarino I./titolo:Modulation of cellular migration and survival by c-Myc through the downregulation of urokinase (uPA) and uPA receptor/doi:10.1128%2FMCB.01442-09/rivista:Molecular and cellular biology (Print)/anno:2010/pagina_da:1838/pagina_a:1851/intervallo_pagine:1838–1851/volume:30
30 (2010): 1838–1851. doi:10.1128/MCB.01442-09
info:cnr-pdr/source/autori:Alfano D.; Votta G.; Schulze A.; Downward J.; Caputi M.; Stoppelli M.P.; Iaccarino I./titolo:Modulation of cellular migration and survival by c-Myc through the downregulation of urokinase (uPA) and uPA receptor/doi:10.1128%2FMCB.01442-09/rivista:Molecular and cellular biology (Print)/anno:2010/pagina_da:1838/pagina_a:1851/intervallo_pagine:1838–1851/volume:30
It has been proposed that c-Myc proapoptotic activity accounts for most of its restraint of tumor formation. We established a telomerase-immortalized human epithelial cell line expressing an activatable c-Myc protein. We found that c-Myc activation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd84d8da8a9ae202a747fb8b11787e27
https://doi.org/10.1128/mcb.01442-09
https://doi.org/10.1128/mcb.01442-09