Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Daniela Ahl"'
Autor:
Summon Koul, Suresh Kurhade, Sandeep Bhosale, Keshav Naik, Videsh Salunkhe, Sudhir Ravula, Prasad Punde, Ravikumar Velayutham, Atul Tiwari, Daniela Ahl, Srividya Malkapuram, Vamsi Mudagala, Amol Raje, Dhananjay Umrani, Suhas Tambe, Poonam Patil, Umesh Singh, Debnath Bhuniya, Narayanan Hariharan, Kasim Mookhtiar
Publikováno v:
Bioorganicmedicinal chemistry letters. 62
A series of novel spirocyclic DGAT1 inhibitors containing the oxadiazole motif were designed and synthesized for biological evaluation. Several compounds exhibited potent diacylglycerol acyltransferase 1 (DGAT1) inhibitory activity. Optimization of t
Autor:
Kensuke Noma, Ping Yen Liu, Yukio Hiroi, Pilar Alcaide, Francis W. Luscinskas, Guijun Yan, James K. Liao, Naotsugu Oyama, Ryuji Okamoto, Yoshiyuki Rikitake, Daniela Ahl, Jianxin Sun, Naoki Sawada, Koichi Shimizu, Hong-Wei Wang
Publikováno v:
Journal of Clinical Investigation. 118:1632-1644
Although Rho-associated kinase (ROCK) activity has been implicated in cardiovascular diseases, the tissue- and isoform-specific roles of ROCKs in the vascular response to injury are not known. To address the role of ROCKs in this process, we generate
Publikováno v:
Circulation Research. 98:1134-1140
Mammalian cells respond to bacterial lipopolysaccharide (LPS) through a cognate receptor: Toll-like receptor 4 (TLR4). The signaling pathways, which link TLR4 to the proinflammatory transcription factor nuclear factor κB (NF-κB), occur through the