Successful fishing for nucleus pulposus progenitor cells of the intervertebral disc across species

Autor: Daisuke Sakai, Jordy Schol, Frances C. Bach, Adel Tekari, Nobuho Sagawa, Yoshihiko Nakamura, Samantha C.W. Chan, Tomoko Nakai, Laura B. Creemers, Daniela A. Frauchiger, Rahel D. May, Sibylle Grad, Masahiko Watanabe, Marianna A. Tryfonidou, Benjamin Gantenbein

Publikováno v: JOR Spine, Vol 1, Iss 2, Pp n/a-n/a (2018)

Background Recently, Tie2/TEK receptor tyrosine kinase (Tie2 or syn. angiopoietin‐1 receptor) positive nucleus pulposus progenitor cells were detected in human, cattle, and mouse. These cells show remarkable multilineage differentiation capacity an

Externí odkaz: https://doaj.org/article/f4cae7a3c9014c9f88a26f0e692748ea

Inhibitory Effects of Human Primary Intervertebral Disc Cells on Human Primary Osteoblasts in a Co-Culture System

Autor: Rahel D. May, Daniela A. Frauchiger, Christoph E. Albers, Lorin M. Benneker, Sandro Kohl, Benjamin Gantenbein

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 4, p 1195 (2018)

Spinal fusion is a common surgical procedure to address a range of spinal pathologies, like damaged or degenerated discs. After the removal of the intervertebral disc (IVD), a structural spacer is positioned followed by internal fixation, and fusion

Externí odkaz: https://doaj.org/article/b537432b69224946924e32aad9d979c3

Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype

Autor: Daniela Angelika Frauchiger, Rahel Deborah May, Christoph E. Albers, Benjamin Gantenbein, Willy Hofstetter

Publikováno v: Neurospine
May, Rahel D.; Frauchiger, Daniela A.; Albers, Christoph E.; Hofstetter, Wilhelm; Gantenbein, Benjamin (2020). Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype. Neurospine, 17(1), pp. 77-87. Korean Spinal Neurosurgery Society 10.14245/ns.2040002.001
Neurospine, Vol 17, Iss 1, Pp 77-87 (2020)

Objective: Spinal fusion surgery is a common treatment modality for various pathologic conditions of the spine. The bone morphogenetic protein 2 (BMP2) analogue L51P acts as a general inhibitor of BMP antagonists, whereas it shows a weak affinity for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de496bf994fdc76ce9a15230ae49d0d
https://pubmed.ncbi.nlm.nih.gov/32252157

Biologic response of human anterior cruciate ligamentocytes on collagen-patches to platelet-rich plasma formulations with and without leucocytes

Autor: Benjamin Gantenbein, Anna Krismer, Rahel Deborah May, Sandro Kohl, Sufian S. Ahmad, Romina Silvia Cabra, Daniela Angelika Frauchiger

Publikováno v: Journal of Orthopaedic Research. 35:2733-2739

Due to the poor self-healing capacities of the anterior cruciate ligament, previous primary repair attempts have failed. To enhance biologic healing, platelet rich plasma and collagen scaffold have shown promise in animal models. Platelet rich plasma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0bbc34e11071b3ad90c319fb0bdc5fe
https://doi.org/10.1002/jor.23599

Developing Bioreactors to Host Joint-Derived Tissues That Require Mechanical Stimulation

Autor: Ezgi Bakirci, Urs Rohrer, Rahel Deborah May, Benjamin Gantenbein, Sibylle Grad, Daniela Angelika Frauchiger

Demographics of the Western Societies points toward an elderly population in need of research on replacement parts for joints and their components, such as the meniscus, cartilage, ligaments, tendons, and intervertebral discs. There is a lack of basi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e6f5142846953993efff5ecc0347ba
https://doi.org/10.1016/b978-0-12-801238-3.65611-8