Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Daniela, Volpato"'
Autor:
Daniela Volpato, Michael Kauk, Regina Messerer, Marcel Bermudez, Gerhard Wolber, Andreas Bock, Carsten Hoffmann, Ulrike Holzgrabe
Publikováno v:
ACS Omega, Vol 5, Iss 49, Pp 31706-31715 (2020)
Externí odkaz:
https://doaj.org/article/55966c345eea4d7fa31c119748db2bb7
Autor:
Carlo Matera, Michael Kauk, Davide Cirillo, Marco Maspero, Claudio Papotto, Daniela Volpato, Ulrike Holzgrabe, Marco De Amici, Carsten Hoffmann, Clelia Dallanoce
Publikováno v:
Molecules, Vol 28, Iss 5, p 2407 (2023)
In the last few years, fluorescence resonance energy transfer (FRET) receptor sensors have contributed to the understanding of GPCR ligand binding and functional activation. FRET sensors based on muscarinic acetylcholine receptors (mAChRs) have been
Externí odkaz:
https://doaj.org/article/448640a720154459b4d602372ed6bc63
Autor:
Daniela Volpato, Ulrike Holzgrabe
Publikováno v:
Molecules, Vol 23, Iss 12, p 3230 (2018)
The cholinergic hypothesis has been reported first being the cause of memory dysfunction in the Alzheimer’s disease. Researchers around the globe have focused their attention on understanding the mechanisms of how this complicated system contribute
Externí odkaz:
https://doaj.org/article/f21ff456a9da450e8f3f4b7bcfd79117
Autor:
Ulrike Zabel, Carsten Hoffmann, Jessika Klöckner, Susanne Nuber, Michael Kauk, Regina Messerer, Maria Consuelo Alonso Canizal, Daniela Volpato, Ulrike Holzgrabe
Publikováno v:
ACS Chemical Biology. 12:833-843
Aiming to design partial agonists as well as allosteric modulators for the M1 muscarinic acetylcholine (M1AChR) receptor, two different series of bipharmacophoric ligands and their structural analogues were designed and synthesized. The hybrids were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4d2fb6fd669960d0cf18f1b3cbbc4a2
https://doi.org/10.1021/acschembio.6b00828
https://doi.org/10.1021/acschembio.6b00828
Autor:
Marco, Maspero, Daniela, Volpato, Davide, Cirillo, Natalia, Yuan Chen, Regina, Messerer, Christoph, Sotriffer, Marco, De Amici, Ulrike, Holzgrabe, Clelia, Dallanoce
Publikováno v:
Bioorganic chemistry. 96
We synthesized a set of new hybrid derivatives (7-C8, 7-C10, 7-C12 and 8-C8, 8-C10, 8-C12), in which a polymethylene spacer chain of variable length connected the pharmacophoric moiety of xanomeline, an M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd8567dd409e4e2770f8be1b430860d8
https://pubmed.ncbi.nlm.nih.gov/32032848
https://pubmed.ncbi.nlm.nih.gov/32032848
Autor:
Clelia Dallanoce, Ulrike Holzgrabe, Marco Maspero, Marco De Amici, Regina Messerer, Natalia Yuan Chen, Christoph A. Sotriffer, Davide Cirillo, Daniela Volpato
Publikováno v:
Bioorganic Chemistry. 96:103633
We synthesized a set of new hybrid derivatives (7-C8, 7-C10, 7-C12 and 8-C8, 8-C10, 8-C12), in which a polymethylene spacer chain of variable length connected the pharmacophoric moiety of xanomeline, an M1/M4-preferring orthosteric muscarinic agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb232453abed55c027a83968ccead37f
https://doi.org/10.1016/j.bioorg.2020.103633
https://doi.org/10.1016/j.bioorg.2020.103633
Autor:
Regina, Messerer, Michael, Kauk, Daniela, Volpato, Maria Consuelo, Alonso Canizal, Jessika, Klöckner, Ulrike, Zabel, Susanne, Nuber, Carsten, Hoffmann, Ulrike, Holzgrabe
Publikováno v:
ACS chemical biology. 12(3)
Aiming to design partial agonists as well as allosteric modulators for the M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::542ef3a06c366d7a0b6bd5560572964d
https://pubmed.ncbi.nlm.nih.gov/28117571
https://pubmed.ncbi.nlm.nih.gov/28117571