Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniela, Unterleuthner"'
Autor:
Victoria Stary, Brigitte Wolf, Daniela Unterleuthner, Julia List, Merjem Talic, Andrea Beer, Johanna Strobl, Georg Stary
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Tumor-associated macrophages (TAM) constitute the most abundant immune cells in the tumor stroma initiating pro-inflammatory (M1) or immunosuppressive (M2) responses depending on their polarization status. Advances in tumor immunotherapy c
Externí odkaz:
https://doaj.org/article/fc014e54b342407db18e5da1ebe6a6ee
Autor:
Johannes Laengle, Andrea Beer, Daniela Unterleuthner, Merjem Talic, Brigitte Wolf, J. Strobl, Georg Stary, Michael Bergmann, Helmut Dolznig, Julia List, Victoria Stary
Publikováno v:
Journal for Immunotherapy of Cancer
BackgroundTumor-associated macrophages (TAM) constitute the most abundant immune cells in the tumor stroma initiating pro-inflammatory (M1) or immunosuppressive (M2) responses depending on their polarization status. Advances in tumor immunotherapy ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62984151a635550d402be9a3544fec90
http://europepmc.org/articles/PMC7437887
http://europepmc.org/articles/PMC7437887
Autor:
B Prieler, Daniela Unterleuthner, Wolfgang Sommergruber, Nina Kramer, Helmut Dolznig, Ilija Crncec, Martin Scherzer, J Schmöllerl, Markus Hengstschläger, Julia Schüler, Harini Nivarthi, Thomas Schwarz, D Lenhardt, Angelika Riedl, Christine Unger, Xiaonan Han, Albin Rudisch, Matthias Artaker, Richard Moriggl, Robert Eferl
Publikováno v:
Oncogene. 36:5460-5472
The canonical WNT signaling pathway is crucial for intestinal stem cell renewal and aberrant WNT signaling is an early event in colorectal cancer (CRC) development. Here, we show for the first time that WNT2 is one of the most significantly induced g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8897b7a3554c4e2d29debb1d4a380f5
https://doi.org/10.1038/onc.2017.144
https://doi.org/10.1038/onc.2017.144
Autor:
Nyamdelger Sukhbaatar, Daniela Unterleuthner, Markus Hengstschläger, Michael Bergmann, Michaela Lang, Andreas Bergthaler, Karl Katholnig, Thomas Weichhart, Mark A. Magnuson, Birgit Schütz, Julia M. Matschinger, Merima Herac, Helmut Dolznig, David Schörghofer, Gernot Schabbauer, Stephanie D. Fritsch, Mario Mikula, Monika Linke, Andreas Spittler, Martin Hirtl
The mechanistic target of rapamycin complex 2 (mTORC2) is a potentially novel and promising anticancer target due to its critical roles in proliferation, apoptosis, and metabolic reprogramming of cancer cells. However, the activity and function of mT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfff9be1d35172b4f01bdd6a30120c8c
https://europepmc.org/articles/PMC6824305/
https://europepmc.org/articles/PMC6824305/
Autor:
Victoria Stary, Daniela Unterleuthner, Michael Bergmann, Brigitte Wolf, Helmut Dolznig, J. Strobl, M. Talic, Andrea Beer
Publikováno v:
European Journal of Cancer. 110:S32-S33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff37b8245fd12d0abf977ea15019847a
https://doi.org/10.1016/j.ejca.2019.01.097
https://doi.org/10.1016/j.ejca.2019.01.097
Autor:
Daniela Unterleuthner, Helmut Dolznig, Karoline Pudelko, Alexandra Burian, Nina Kramer, Markus Hengstschläger
Publikováno v:
SLAS discovery : advancing life sciences RD. 22(5)
Angiogenesis is a promising target for anticancer therapies, but also for treating other diseases with pathologic vessel development. Targeting the vascular endothelial growth factor (VEGF) pathway did not proof as effective as expected due to emergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a33d2269a383325c3e671884b6a731
https://pubmed.ncbi.nlm.nih.gov/28346097
https://pubmed.ncbi.nlm.nih.gov/28346097
Autor:
Markus Hengstschläger, Christine Unger, Dagmar Schwanzer-Pfeiffer, Martin Scherzer, Helmut Dolznig, Nina Kramer, Angelika Walzl, Daniela Unterleuthner
Publikováno v:
SLAS Discovery. 19:1047-1059
Spheroid-based cellular screening approaches represent a highly physiologic experimental setup to identify novel anticancer drugs and an innovative preclinical model to reduce the high failure rate of anticancer compounds in clinical trials. The resa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779840c0f6333ae8d13c6c13da94935d
https://doi.org/10.1177/1087057114532352
https://doi.org/10.1177/1087057114532352
Autor:
Daniela Unterleuthner, Markus Hengstschläger, D Lenhardt, Angelika Riedl, Martin Scherzer, Helmut Dolznig, Andreas Wernitznig, Alexandra Burian, Albin Rudisch, Michaela Schlederer, Stefanie Walter, Julia Schüler, Wolfgang Sommergruber, Nina Kramer, Lukas Kenner, Christine Unger, Mira Stadler
Publikováno v:
Oncogene. 36(38)
The insulin-like growth factor (IGF)2/IGF1 receptor (IGF1R) signaling axis has an important role in intestinal carcinogenesis and overexpression of IGF2 is an accepted risk factor for colorectal cancer (CRC) development. Genetic amplifications and lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b0f944b35124749946f6aec54fb2a5
https://pubmed.ncbi.nlm.nih.gov/28534511
https://pubmed.ncbi.nlm.nih.gov/28534511
Autor:
Angelika, Riedl, Michaela, Schlederer, Karoline, Pudelko, Mira, Stadler, Stefanie, Walter, Daniela, Unterleuthner, Christine, Unger, Nina, Kramer, Markus, Hengstschläger, Lukas, Kenner, Dagmar, Pfeiffer, Georg, Krupitza, Helmut, Dolznig
Publikováno v:
Journal of cell science. 130(1)
Three-dimensional (3D) cancer models are used as preclinical systems to mimic physiologic drug responses. We provide evidence for strong changes of proliferation and metabolic capacity in three dimensions by systematically analyzing spheroids of colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::566c1a6a7b882fbe3f2da89bc6a4af17
https://pubmed.ncbi.nlm.nih.gov/27663511
https://pubmed.ncbi.nlm.nih.gov/27663511
Autor:
Stefanie Walter, Mira Stadler, Markus Hengstschläger, Daniela Unterleuthner, Angelika Riedl, Georg Krupitza, Helmut Dolznig, Lukas Kenner, Michaela Schlederer, Christine Unger, Karoline Pudelko, Dagmar Pfeiffer, Nina Kramer
Publikováno v:
Journal of Cell Science.
Three-dimensional (3D) cancer models are used as preclinical systems to mimic physiologic drug responses. We provide evidence for strong changes of proliferation and metabolic capacity in three dimensions by systematically analyzing spheroids of colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e506334879a9ed354dd8511d4997e20
https://doi.org/10.1242/jcs.188102
https://doi.org/10.1242/jcs.188102