Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Daniela, Turchetti"'
Autor:
Floriana Jessica Di Paola, Chiara Alquati, Gabriele Conti, Giulia Calafato, Silvia Turroni, Federica D’Amico, Claudio Ceccarelli, Francesco Buttitta, Alice Bernardi, Dajana Cuicchi, Gilberto Poggioli, Daniela Turchetti, Simona Ferrari, Renato Cannizzaro, Stefano Realdon, Patrizia Brigidi, Luigi Ricciardiello
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Wnt/β-catenin signalling impairment accounts for 85% of colorectal cancers (CRCs), including sporadic and familial adenomatous polyposis (FAP) settings. An altered PI3K/mTOR pathway and gut microbiota also contribute to CRC carci
Externí odkaz:
https://doaj.org/article/60dce2c7bcdb47c6a9cb5921806c13e1
Autor:
Corrado Tinterri, Damiano Gentile, Francesco Caruso, Laura Cortesi, Michelino De Laurentiis, Lucio Fortunato, Donatella Santini, Daniela Turchetti, Alberta Ferrari, Alberto Zambelli, Senonetwork Italia Breast Centre Responders
Publikováno v:
Current Oncology, Vol 31, Iss 7, Pp 3815-3825 (2024)
Background: Breast units (BUs) provide breast cancer (BC) care, including prevention, treatment, and genetic assessment. Genetic research has highlighted BRCA1/2 mutations as key hereditary BC risk factors. BRCA testing is crucial for personalized tr
Externí odkaz:
https://doaj.org/article/177071785326463e8f74fe783572eec4
Autor:
Giovanni Innella, Cristina Fortuno, Laura Caleca, Bing‐Jian Feng, Courtney Carroll, Michael T. Parsons, Sara Miccoli, Marco Montagna, Daniele Calistri, Laura Cortesi, Barbara Pasini, Siranoush Manoukian, Daniela Giachino, Laura Matricardi, Maria Cristina Foti, Valentina Zampiga, Claudia Piombino, Elena Barbieri, Francesca Vignolo Lutati, Jacopo Azzolini, Rita Danesi, Valentina Arcangeli, Sandrine M. Caputo, Nadia Boutry‐Kryza, Vincent Goussot, Susan Hiraki, Marcy Richardson, Hereditary Breast/Ovarian Cancer IOV network (HBOC IOVnet), Simona Ferrari, Paolo Radice, Amanda B. Spurdle, Daniela Turchetti
Publikováno v:
Cancer Medicine, Vol 13, Iss 16, Pp n/a-n/a (2024)
Abstract Background BRCA1:c.5017_5019del (p.His1673del) is a founder variant relatively frequent in Northern Italy. Despite previous suggestion of pathogenicity, variant classification in public databases is still conflicting, needing additional evid
Externí odkaz:
https://doaj.org/article/32f976e151b24f91bbf40981195926b1
Autor:
Giulia Olivucci, Emanuela Iovino, Giovanni Innella, Daniela Turchetti, Tommaso Pippucci, Pamela Magini
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The clinical application of technological progress in the identification of DNA alterations has always led to improvements of diagnostic yields in genetic medicine. At chromosome side, from cytogenetic techniques evaluating number and gross structura
Externí odkaz:
https://doaj.org/article/1824b60ae34e4ed3918ab0901427b3ca
Autor:
Stefano Ferretti, Priscilla Sassoli de Bianchi, Debora Canuti, Cinzia Campari, Laura Cortesi, Valentina Arcangeli, Elena Barbieri, Cecilia D’Aloia, Rita Danesi, Pierandrea De Iaco, Margherita De Lillo, Laura Lombardo, Gabriella Moretti, Antonino Musolino, Dante Palli, Caterina Palmonari, Mila Ravegnani, Alfredo Tafà, Alessandra Tononi, Daniela Turchetti, Claudio Zamagni, Valentina Zampiga, Lauro Bucchi, the HBOC Study Group
Publikováno v:
Methods and Protocols, Vol 7, Iss 4, p 63 (2024)
Hereditary breast/ovarian cancer (HBOC) syndrome is caused by the inheritance of monoallelic germline BRCA1/2 gene mutations. If BRCA1/2 mutation carriers are identified before the disease develops, effective actions against HBOC can be taken, includ
Externí odkaz:
https://doaj.org/article/45a7886160724011a27d7da7efcaef86
Autor:
Thais Maloberti, Antonio De Leo, Viviana Sanza, Lidia Merlo, Michela Visani, Giorgia Acquaviva, Sara Coluccelli, Annalisa Altimari, Elisa Gruppioni, Stefano Zagnoni, Daniela Turchetti, Sara Miccoli, Michelangelo Fiorentino, Antonietta D’Errico, Dario de Biase, Giovanni Tallini
Publikováno v:
Journal of Molecular Pathology, Vol 3, Iss 3, Pp 115-124 (2022)
Several causes may lead to CRC, either extrinsic (sporadic forms) or genetic (hereditary forms), such as Lynch syndrome (LS). Most sporadic deficient mismatch repair (dMMR) CRC cases are characterized by the methylation of the MLH1 promoter gene and/
Externí odkaz:
https://doaj.org/article/3450d41abacb4cdbbad985255de255c7
Autor:
Dario de Biase, Thais Maloberti, Angelo Gianluca Corradini, Francesca Rosini, Marco Grillini, Martina Ruscelli, Sara Coluccelli, Annalisa Altimari, Elisa Gruppioni, Viviana Sanza, Daniela Turchetti, Andrea Galuppi, Martina Ferioli, Susanna Giunchi, Giulia Dondi, Marco Tesei, Gloria Ravegnini, Francesca Abbati, Daniela Rubino, Claudio Zamagni, Pierandrea De Iaco, Donatella Santini, Claudio Ceccarelli, Anna Myriam Perrone, Giovanni Tallini, Antonio De Leo
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionThe European Society of Gynecologic Oncology/European Society of Radiation Therapy and Oncology/European Society of Pathology (ESGO/ESTRO/ESP) committee recently proposed a new risk stratification system for endometrial carcinoma (EC) pat
Externí odkaz:
https://doaj.org/article/636a6ccb0216497ab54dc7a9845d8fa7
Autor:
Thais Maloberti, Antonio De Leo, Sara Coluccelli, Viviana Sanza, Elisa Gruppioni, Annalisa Altimari, Stefano Zagnoni, Francesca Giunchi, Francesco Vasuri, Michelangelo Fiorentino, Veronica Mollica, Simona Ferrari, Sara Miccoli, Michela Visani, Daniela Turchetti, Francesco Massari, Giovanni Tallini, Dario de Biase
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8940 (2023)
Despite significant therapeutic advances, metastatic CRPC (mCRPC) remains a lethal disease. Mutations in homologous recombination repair (HRR) genes are frequent in mCRPC, and tumors harboring these mutations are known to be sensitive to PARP inhibit
Externí odkaz:
https://doaj.org/article/829456da970f4a4cbb0c9c4831f630b8
Autor:
Laura Cortesi, Bruna Baldassarri, Stefano Ferretti, Elisabetta Razzaboni, Mariangela Bella, Lauro Bucchi, Debora Canuti, Pierandrea De Iaco, Giorgio De Santis, Fabio Falcini, Vania Galli, Lea Godino, Maurizio Leoni, Anna Myriam Perrone, Marco Pignatti, Gianni Saguatti, Donatella Santini, Priscilla Sassoli de'Bianchi, Federica Sebastiani, Mario Taffurelli, Giovanni Tazzioli, Daniela Turchetti, Claudio Zamagni, Carlo Naldoni
Publikováno v:
Cancer Medicine, Vol 9, Iss 7, Pp 2579-2589 (2020)
Abstract Background Up to 10% of individuals with breast cancer (BC) belong to families with hereditary syndromes. The aim of this study was to develop an instrument to identify individuals/families at high‐hereditary risk for BC and offer dedicate
Externí odkaz:
https://doaj.org/article/af5aedd27bb04bc5a29867b466c7c92f
Autor:
Pasquale Paolisso, Giulia Saturi, Alberto Foà, Maristella Saponara, Margherita Nannini, Maria Abbondanza Pantaleo, Ornella Leone, Daniela Turchetti, Daniele Calistri, Carlo Savini, Davide Pacini, Carmine Pizzi, Nazzareno Galiè
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-6 (2020)
Abstract Background This case represents the first report of malignant primary cardiac tumour in a patient with Lynch Syndrome associated with MSH2 pathogenic variant. Case presentation A 57-year-old woman with previous ovarian cystadenocarcinoma was
Externí odkaz:
https://doaj.org/article/36ffae686eab4974813f0a123a138575