Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Daniela, Schuster"'
Autor:
Silvia Fibi-Smetana, Camila Inglis, Daniela Schuster, Nina Eberle, José Luis Granados-Soler, Wen Liu, Saskia Krohn, Christian Junghanss, Ingo Nolte, Leila Taher, Hugo Murua Escobar
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Targeted next-generation sequencing (NGS) enables the identification of genomic variants in cancer patients with high sensitivity at relatively low costs, and has thus opened the era to personalized human oncology. Veterinary medicine tends to adopt
Externí odkaz:
https://doaj.org/article/25e9204043184b0a9c92b84f47e11d65
Autor:
Lisa Vieider, Eva Zoeller, Erik Romp, Martin Schoenthaler, Victor Hernández-Olmos, Veronika Temml, Thomas Hasenoehrl, Daniela Schuster, Oliver Werz, Ulrike Garscha, Barbara Matuszczak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1752-1764 (2022)
A series of derivatives of the potent dual soluble epoxide hydrolase (sEH)/5-lipoxygenase-activating protein (FLAP) inhibitor diflapolin was designed, synthesised, and characterised. These novel compounds, which contain a benzimidazole subunit were e
Externí odkaz:
https://doaj.org/article/64d4071fa89c41b3835b8c14b9c7eab6
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1468 (2023)
Different dopamine receptor (DR) subtypes are involved in pathophysiological conditions such as Parkinson’s Disease (PD), schizophrenia and depression. While many DR-targeting drugs have been approved by the U.S. Food and Drug Administration (FDA),
Externí odkaz:
https://doaj.org/article/5084bd56c5f9431aa60bab9c0f433eb3
Publikováno v:
Molecules, Vol 27, Iss 14, p 4435 (2022)
Diseases of the central nervous system are an alarming global problem showing an increasing prevalence. Dopamine receptor D2 (D2R) has been shown to be involved in central nervous system diseases. While different D2R-targeting drugs have been approve
Externí odkaz:
https://doaj.org/article/1db22ed3e414403ea8b19239e8d1cc1d
Autor:
Veronika Temml, Jakub Kollár, Theresa Schönleitner, Anna Höll, Daniela Schuster, Zsófia Kutil
Publikováno v:
Journal of Chemical Information and Modeling. 63:1249-1259
Autor:
Ludwig Aigner, Frank Pietrantonio, Diana Marisa Bessa de Sousa, Johanna Michael, Daniela Schuster, Herbert Anton Reitsamer, Horst Zerbe, Michael Studnicka
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
The emergence and global impact of COVID-19 has focused the scientific and medical community on the pivotal influential role of respiratory viruses as causes of severe pneumonia, on the understanding of the underlying pathomechanisms, and on potentia
Externí odkaz:
https://doaj.org/article/abbe64e553144879a3249cb3e45c1936
Autor:
Gabriele Möller, Veronika Temml, Antonio Cala Peralta, Océane Gruet, Pascal Richomme, Denis Séraphin, Guillaume Viault, Luisa Kraus, Petra Huber-Cantonati, Elisabeth Schopfhauser, Johanna Pachmayr, Janina Tokarz, Daniela Schuster, Jean-Jacques Helesbeux, Kenneth Allen Dyar
Publikováno v:
Metabolites, Vol 12, Iss 2, p 99 (2022)
Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against prostate cancer cell lines through various mechanisms or targets. Based on the literature and prel
Externí odkaz:
https://doaj.org/article/2ab68851bb2c41d1830b279e836dcadf
Autor:
Helmut Pein, Alexia Ville, Simona Pace, Veronika Temml, Ulrike Garscha, Martin Raasch, Khaled Alsabil, Guillaume Viault, Chau-Phi Dinh, David Guilet, Fabiana Troisi, Konstantin Neukirch, Stefanie König, Rosella Bilancia, Birgit Waltenberger, Hermann Stuppner, Maria Wallert, Stefan Lorkowski, Christina Weinigel, Silke Rummler, Marc Birringer, Fiorentina Roviezzo, Lidia Sautebin, Jean-Jacques Helesbeux, Denis Séraphin, Alexander S. Mosig, Daniela Schuster, Antonietta Rossi, Pascal Richomme, Oliver Werz, Andreas Koeberle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Vitamin E metabolites are proposed to have signalling capacity, but how they may regulate immune responses is still unclear. Here the authors show that a vitamin E metabolite, α-T-13′-COOH, can inhibit 5-lipoxygenase and thereby suppress the synth
Externí odkaz:
https://doaj.org/article/8f5b1e43017943509f14b4b68fe07ec5
Autor:
Judith Hagenbuchner, Veronika Obsilova, Teresa Kaserer, Nora Kaiser, Bettina Rass, Katarina Psenakova, Vojtech Docekal, Miroslava Alblova, Klara Kohoutova, Daniela Schuster, Tatsiana Aneichyk, Jan Vesely, Petra Obexer, Tomas Obsil, Michael J Ausserlechner
Publikováno v:
eLife, Vol 8 (2019)
FOXO transcription factors are critical regulators of cell homeostasis and steer cell death, differentiation and longevity in mammalian cells. By combined pharmacophore-modeling-based in silico and fluorescence polarization-based screening we identif
Externí odkaz:
https://doaj.org/article/2a1679493eee41128e3edfeaf260a091
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1529-1536 (2018)
There is an increasing interest in developing novel eosinophil peroxidase (EPO) inhibitors, in order to provide new treatment strategies against chronic inflammatory and neurodegenerative diseases caused by eosinophilic disorder. Within this study, a
Externí odkaz:
https://doaj.org/article/fbffca2cf5c94eb8b384f2e2d5caa111