Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Daniela, Kramer"'
Autor:
Philipp Knopf, Dimitri Stowbur, Sabrina H. L. Hoffmann, Natalie Hermann, Andreas Maurer, Valentina Bucher, Marilena Poxleitner, Bredi Tako, Dominik Sonanini, Balaji Krishnamachary, Sanhita Sinharay, Birgit Fehrenbacher, Irene Gonzalez-Menendez, Felix Reckmann, David Bomze, Lukas Flatz, Daniela Kramer, Martin Schaller, Stephan Forchhammer, Zaver M. Bhujwalla, Leticia Quintanilla-Martinez, Klaus Schulze-Osthoff, Mark D. Pagel, Marieke F. Fransen, Martin Röcken, André F. Martins, Bernd J. Pichler, Kamran Ghoreschi, Manfred Kneilling
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L
Externí odkaz:
https://doaj.org/article/b3fa661fa2c8409a83b991ccda94efe7
Autor:
Berenice Fischer, Tanja Kübelbeck, Antonia Kolb, Julia Ringen, Ari Waisman, Miriam Wittmann, Susanne Karbach, Stephan Marcus Kölsch, Daniela Kramer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Plaque psoriasis is an autoinflammatory and autoimmune skin disease, affecting 1-3% of the population worldwide. Previously, high levels of IL-36 family cytokines were found in psoriatic skin lesions, thereby contributing to keratinocyte hyperprolife
Externí odkaz:
https://doaj.org/article/c09af3e842354597b44bb3049b851775
Autor:
Katharina M. A. Gabriel, Steffi Jírů-Hillmann, Peter Kraft, Udo Selig, Viktoria Rücker, Johannes Mühler, Klaus Dötter, Matthias Keidel, Hassan Soda, Alexandra Rascher, Rolf Schneider, Mathias Pfau, Roy Hoffmann, Joachim Stenzel, Mohamed Benghebrid, Tobias Goebel, Sebastian Doerck, Daniela Kramer, Karl Georg Haeusler, Jens Volkmann, Peter U. Heuschmann, Felix Fluri
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Telemedicine improves the quality of acute stroke care in rural regions with limited access to specialized stroke care. We report the first 2 years’ experience of implementing a comprehensive telemedical stroke network comprisin
Externí odkaz:
https://doaj.org/article/40bc2b133ef948faa9611d06301dca91
Autor:
Julia Nehls, Ramona Businger, Markus Hoffmann, Constantin Brinkmann, Birgit Fehrenbacher, Martin Schaller, Brigitte Maurer, Caroline Schönfeld, Daniela Kramer, Stephan Hailfinger, Stefan Pöhlmann, Michael Schindler
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1841-1853.e6 (2019)
Summary: The Ebola virus glycoprotein (EBOV-GP) forms GP-containing microvesicles, so-called virosomes, which are secreted from GP-expressing cells. However, determinants of GP-virosome release and their functionality are poorly understood. We charac
Externí odkaz:
https://doaj.org/article/07bc6b29896e4290af031e69a39cda9f
Publikováno v:
Pediatric Dermatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2822eb2b7ecefc358bbe792c52dee93
https://doi.org/10.1111/pde.15339
https://doi.org/10.1111/pde.15339
Autor:
Julia Ringen, Theresa Schaller, Berenice Fischer, Daniela Kramer, Katharina Perius, Tabea Bieler, Katharina Kommoss, Tanja Knopp, Andreas Daiber, Thomas Münzel, Philip Wenzel, Ari Waisman, Susanne Karbach, Johannes Wild
Publikováno v:
Free Radical Biology and Medicine. 201:7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::843f8d2cc4d62bb5ca9eab2fa255db06
https://doi.org/10.1016/j.freeradbiomed.2023.03.052
https://doi.org/10.1016/j.freeradbiomed.2023.03.052
Autor:
Nurcan Üçeyler, Nils Schröter, Waldemar Kafke, Daniela Kramer, Christoph Wanner, Frank Weidemann, Claudia Sommer
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166484 (2016)
The X-chromosomally linked life-limiting Fabry disease (FD) is associated with deposits of the sphingolipid globotriaosylceramide 3 (Gb3) in various tissues. Skin is easily accessible and may be used as an additional diagnostic and follow-up medium.
Externí odkaz:
https://doaj.org/article/895b79f75aa841f09d8cc67a7701d967
Autor:
Matthias Dobbelstein, Antje Dickmanns, Anne Müller, Daniela Kramer, Knut Schäkel, Stephan Hailfinger, Klaus Schulze-Osthoff, Claudia Resch
Publikováno v:
J Clin Invest
Psoriasis is a frequent, inflammatory skin disease characterized by keratinocyte hyperproliferation and a disease-related infiltration of immune cells. Here, we identified a novel proinflammatory signaling pathway driven by cyclin-dependent kinase 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a0116af4b0d8578b983f9877a85a0d
https://doi.org/10.1172/jci134217
https://doi.org/10.1172/jci134217
Autor:
Kamran Ghoreschi, Wolfgang M. Thaiss, Harald Carlsen, Roman Mehling, Stephan Hailfinger, Hasan Halit Öz, Bernd J. Pichler, Martin Röcken, Manfred Kneilling, Johannes Schwenck, Klaus Schulze-Osthoff, Leticia Quintanilla-Martinez, Daniela Kramer, Dominik Hartl, Irene Gonzalez Menendez
Publikováno v:
Molecular Imaging and Biology
Purpose Reactive oxygen and nitrogen species (ROS/RNS) production and the NF-κB activation are critically involved in inflammatory responses, but knowledge about the temporal dynamics during acute and chronic inflammation is limited. Here, we presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7931110632e716331c8f6bb5ddd05569
https://doi.org/10.1007/s11307-019-01412-8
https://doi.org/10.1007/s11307-019-01412-8
Autor:
Nurcan Uçeyler, György A Homola, Hans Guerrero González, Daniela Kramer, Christoph Wanner, Frank Weidemann, László Solymosi, Claudia Sommer
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87054 (2014)
A high load of white matter lesions and enlarged basilar arteries have been shown in selected patients with Fabry disease, a disorder associated with an increased stroke risk. We studied a large cohort of patients with Fabry disease to differentially
Externí odkaz:
https://doaj.org/article/966c740c76c244b1b81379ab9c8f7329