Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniela, Brodbeck"'
Autor:
Caterina Virginio, Laura Aldegheri, Selena Nola, Daniela Brodbeck, Laurent Brault, Luca F. Raveglia, Alessio Barilli, Mark Sabat, Richard Myers
Publikováno v:
SLAS Discovery, Vol 27, Iss 1, Pp 55-64 (2022)
Transient Receptor Potential Melastatin 5 (TRPM5) is an intracellular calcium-activated cation-selective ion channel expressed in a variety of cell types. Dysfunction of this channel has recently been implied in a range of disease states including di
Externí odkaz:
https://doaj.org/article/4cf64e986b4845aa93cac6e858d386ee
Autor:
Raveglia Luca Francesco, Richard M. Myers, Caterina Virginio, Mark Sabat, Daniela Brodbeck, Laurent Brault, Selena Nola, Alessio Barilli, Laura Aldegheri
Publikováno v:
SLAS Discovery. 27:55-64
Transient Receptor Potential Melastatin 5 (TRPM5) is an intracellular calcium-activated cation-selective ion channel expressed in a variety of cell types. Dysfunction of this channel has recently been implied in a range of disease states including di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feac2b5c5ecd8e0a04d427042b52264e
https://doi.org/10.1016/j.slasd.2021.10.004
https://doi.org/10.1016/j.slasd.2021.10.004
Autor:
Daniela Pompilio, Sabrina Tassini, Laura Piccoli, Alessio Barilli, Aldo Feriani, Daniela Brodbeck, Laura Castelletti, Raveglia Luca Francesco, Laurent Brault, Iain Lingard, Laura Aldegheri, Federica Bianchi, Mark Sabat, Richard M. Myers, Caterina Virginio, Selena Nola, Cristian Salvagno
Publikováno v:
Journal of Medicinal Chemistry. 64:5931-5955
Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a nonselective monovalent cation channel activated by intracellular Ca2+ increase. Within the gastrointestinal system, TRPM5 is expressed in the stoma, small intestine, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::276f841154741494c801408c590e8d10
https://doi.org/10.1021/acs.jmedchem.1c00065
https://doi.org/10.1021/acs.jmedchem.1c00065
Autor:
Alessio, Barilli, Laura, Aldegheri, Federica, Bianchi, Laurent, Brault, Daniela, Brodbeck, Laura, Castelletti, Aldo, Feriani, Iain, Lingard, Richard, Myers, Selena, Nola, Laura, Piccoli, Daniela, Pompilio, Luca F, Raveglia, Cristian, Salvagno, Sabrina, Tassini, Caterina, Virginio, Mark, Sabat
Publikováno v:
Journal of medicinal chemistry. 64(9)
Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a nonselective monovalent cation channel activated by intracellular Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d619050999d16fbf323a8d84594fd590
https://pubmed.ncbi.nlm.nih.gov/33890770
https://pubmed.ncbi.nlm.nih.gov/33890770
Autor:
Daniela Brodbeck, Lorenza Wyder Peters, Marie Goxe, Klaus D. Molle, Urs Regenass, Philippe Guerry, Michael N. Hall, Christoph Moroni, Marco Colombi, Agnes Knopf, Anke Thiemeyer
Publikováno v:
SLAS Discovery. 19:131-144
The mTOR pathway is a critical integrator of nutrient and growth factor signaling. Once activated, mTOR promotes cell growth and proliferation. Several components of the mTOR pathway are frequently deregulated in tumors, leading to constitutive activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95d78737631ff307706600798db189c
https://doi.org/10.1177/1087057113497798
https://doi.org/10.1177/1087057113497798
Publikováno v:
Molecular Biology in Medicinal Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6657eee8bec34dd1d773c21f0b09fb3
https://doi.org/10.1002/3527602666.ch1
https://doi.org/10.1002/3527602666.ch1
Publikováno v:
Journal of Biological Chemistry. 276:29550-29558
We have reported previously the cloning and characterization of human and mouse protein kinase B gamma (PKB gamma), the third member of the PKB family of second messenger-regulated serine/threonine kinases (Brodbeck, D., Cron, P., and Hemmings, B. A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635cdffc7869b195333bacfd8a00f02f
https://doi.org/10.1074/jbc.m104633200
https://doi.org/10.1074/jbc.m104633200
Autor:
Brian A. Hemmings, Roger Meier, Mirjana Andjelkovic, Jongsun Park, Ivana Galetic, Daniela Brodbeck
Publikováno v:
Pharmacology & Therapeutics. 82:409-425
Protein kinase B (PKB) is a member of the second messenger subfamily of protein kinases. The three isoforms of PKB identified have an amino-terminal pleckstrin homology domain, a central kinase domain, and a carboxy-terminal regulatory domain. PKB is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6114dd17d723cdc0c0e61a34318c3e
https://doi.org/10.1016/s0163-7258(98)00071-0
https://doi.org/10.1016/s0163-7258(98)00071-0
Publikováno v:
Journal of Biological Chemistry. 274:9133-9136
We have cloned human protein kinase Bgamma (PKBgamma) and found that it contains two regulatory phosphorylation sites, Thr305 and Ser472, which correspond to Thr308 and Ser473 of PKBalpha. Thus it differs significantly from the previously published r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01e699b0f89c0d8f858edcb9b75e519
https://doi.org/10.1074/jbc.274.14.9133
https://doi.org/10.1074/jbc.274.14.9133
Autor:
Daniela Brodbeck, Markus Affolter, Patrick Callaerts, Remo Amherd, Edith Hintermann, Urs A. Meyer
Publikováno v:
DNA and Cell Biology. 17:621-633
In insects, arylalkylamine N-acetyltransferases (AANATs) have been implicated in several physiological processes, including sclerotization, inactivation of certain neurotransmitters, and, similar to the function in vertebrates, catalysis of the rate-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fdc14a73c4e48593781eaa31665b99a
https://doi.org/10.1089/dna.1998.17.621
https://doi.org/10.1089/dna.1998.17.621