Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daniel Yagoub"'
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169925 (2017)
The annexin family and S100A associated proteins are important regulators of diverse calcium-dependent cellular processes including cell division, growth regulation and apoptosis. Dysfunction of individual annexin and S100A proteins is associated wit
Externí odkaz:
https://doaj.org/article/956448d80ce44ba4bcf485351f1577a7
Autor:
Eileen M McGowan, Nham Tran, Nikki Alling, Daniel Yagoub, Lisa M Sedger, Rosetta Martiniello-Wilks
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42246 (2012)
As part of a cell's inherent protection against carcinogenesis, p14ARF is upregulated in response to hyperproliferative signalling to induce cell cycle arrest. This property makes p14ARF a leading candidate for cancer therapy. This study explores the
Externí odkaz:
https://doaj.org/article/45650bdc53f14cf4a468b86dcdeed210
Autor:
Eileen M McGowan, Nikki Alling, Elise A Jackson, Daniel Yagoub, Nikolas K Haass, John D Allen, Rosetta Martinello-Wilks
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20623 (2011)
Endocrine resistance is a major problem with anti-estrogen treatments and how to overcome resistance is a major concern in the clinic. Reliable measurement of cell viability, proliferation, growth inhibition and death is important in screening for dr
Externí odkaz:
https://doaj.org/article/c4769edbb92241fca571d23707728fef
Autor:
Sophie Lev, Samantha Z. Chia, Joshua J. Hamey, Desmarini Desmarini, Zhiliang Chen, Daniel Yagoub, Yu-Wen Lai, Julianne T. Djordjevic, Marc R. Wilkins, Chi Nam Ignatius Pang, Gene Hart-Smith, Melissa A. Erce
Publikováno v:
Molecular & Cellular Proteomics. 17:2462-2479
Hmt1p is the predominant arginine methyltransferase in Saccharomyces cerevisiae. Its substrate proteins are involved in transcription, transcriptional regulation, nucleocytoplasmic transport and RNA splicing. Hmt1p-catalyzed methylation can also modu
Publikováno v:
Journal of Proteome Research. 17:359-373
The study of post-translational methylation is hampered by the fact that large-scale LC-MS/MS experiments produce high methylpeptide false discovery rates (FDRs). The use of heavy-methyl stable isotope labeling by amino acids in cell culture (heavy-m
Autor:
Daniel L. Winter, Marc R. Wilkins, Christopher M. Overall, Daniel Yagoub, Joshua J. Hamey, Gene Hart-Smith
Publikováno v:
Molecular & Cellular Proteomics. 15:164-176
Eukaryotic elongation factor 1A (eEF1A) is an essential, highly methylated protein that facilitates translational elongation by delivering aminoacyl-tRNAs to ribosomes. Here, we report a new eukaryotic protein N-terminal methyltransferase, Saccharomy
Publikováno v:
PROTEOMICS. 15:3209-3218
The Hmt1 methyltransferase is the predominant arginine methyltransferase in Saccharomyces cerevisiae. There are 18 substrate proteins described for this methyltransferase, however native sites of methylation have only been identified on two of these
Autor:
Daniel Yagoub, Gyorgy Hutvagner, Wengen Wu, Diana Hatoum, Angelina J. Lay, Jack H. Lai, Sarah Bajan, Rosetta Martiniello-Wilks, Dominik Kaczorowski, Marc R. Wilkins, Pu Xia, Eileen M. McGowan
Publikováno v:
Molecular Endocrinology. 28:1899-1915
Sphingosine kinase 1 (SK1) is a signaling enzyme that catalyzes the formation of sphingosine-1-phosphate. Overexpression of SK1 is causally associated with breast cancer progression and resistance to therapy. SK1 inhibitors are currently being invest
Autor:
Samantha Z, Chia, Yu-Wen, Lai, Daniel, Yagoub, Sophie, Lev, Joshua J, Hamey, Chi Nam Ignatius, Pang, Desmarini, Desmarini, Zhiliang, Chen, Julianne T, Djordjevic, Melissa A, Erce, Gene, Hart-Smith, Marc R, Wilkins
Publikováno v:
Molecularcellular proteomics : MCP. 17(12)
Hmt1p is the predominant arginine methyltransferase in Saccharomyces cerevisiae. Its substrate proteins are involved in transcription, transcriptional regulation, nucleocytoplasmic transport and RNA splicing. Hmt1p-catalyzed methylation can also modu
All large scale LC-MS/MS post-translational methylation site discovery experiments require methylpeptide spectrum matches (methyl-PSMs) to be identified at acceptably low false discovery rates (FDRs). To meet estimated methyl-PSM FDRs, methyl-PSM fil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7ef6d0b1ff1ad0ccbedfbbb394e3e0
https://europepmc.org/articles/PMC4813715/
https://europepmc.org/articles/PMC4813715/