Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography

Autor: Vineeta Das, Furu Zhang, Andrew J. Bower, Joanne Li, Tao Liu, Nancy Aguilera, Bruno Alvisio, Zhuolin Liu, Daniel X. Hammer, Johnny Tam

Publikováno v: Communications Medicine, Vol 4, Iss 1, Pp 1-10 (2024)

Abstract Background In vivo imaging of the human retina using adaptive optics optical coherence tomography (AO-OCT) has transformed medical imaging by enabling visualization of 3D retinal structures at cellular-scale resolution, including the retinal

Externí odkaz: https://doaj.org/article/d83ae0fd9aa74ce8bc9566879e38863a

Quantification of Human Photoreceptor–Retinal Pigment Epithelium Macular Topography with Adaptive Optics–Optical Coherence Tomography

Autor: Zhuolin Liu, Samira Aghayee, Somayyeh Soltanian-Zadeh, Katherine Kovalick, Anant Agrawal, Osamah Saeedi, Catherine Cukras, Emily Y. Chew, Sina Farsiu, Daniel X. Hammer

Publikováno v: Diagnostics, Vol 14, Iss 14, p 1518 (2024)

Photoreceptors (PRs) and retinal pigment epithelial (RPE) cells form a functional unit called the PR-RPE complex. The PR-RPE complex plays a critical role in maintaining retinal homeostasis and function, and the quantification of its structure and to

Externí odkaz: https://doaj.org/article/ecc43ef7aa8f4996b89b90b9684bdc48

Longitudinal Choroidal Development in Preterm Infants

Autor: Suzanne M. Michalak, MD, Shwetha Mangalesh, MBBS, Yineng Chen, MS, Liangbo L. Shen, MD, Vincent Tai, MS, Katrina Winter, BS, Neeru Sarin, MD, Gui-shuang Ying, PhD, Cynthia A. Toth, MD, Lejla Vajzovic, MD, Xi Chen, MD, PhD, Charles M. Cotten, MD, Mays Antioine El-Dairi, MD, Sina Farsiu, PhD, Sharon Freedman, MD, Hesham Gabr, MD, Sara Grace, MD, Kathryn E. Gustafson, PhD, Madja Hadziahmetovic, MD, Joseph Izatt, PhD, Ramiro Maldonado, MD, Suzanne Michalak, MD, Matthew O’Sullivan, MD, Sally Ong, MD, Miroslav Pajik, PhD, Carolyn Pizoli, MD, S. Grace Prakalapakorn, MD, Joan Roberts, MD, Alabi Rolake, MD, Cynthia Toth, MD, Nita Valikodath, MD, Christian Viehland, PhD, David Wallace, MD, Xiao Yi Zhou, MD, Michelle McCall, BA, MCAPM, Joanne Finkle, RN, JD, Neeru Sarin, MBBS, Alexandria Dandridge, Ryan Imperio, BS, William Raynor, BS, Du Tran-Viet, BS, Stephanie Chiu, PhD, Heena Divecha, MS, Katrina P. Winter, BS, Kimberly Fisher, PhD, FMP-BC, Lacey Andrews, BS, Melissa Babilonia-Rosa, PhD, Anne Baez Love, BS, Lucy DeStefano-Pearce, MA, Jessicka Hamilton, BA, Grace Jefferson, MS, Amanda Marion, BS, Isabella Pallotto, MPH, Marito Passero, BS, Caitlin Stone, MA, Michelle Sunico, BS, Caelan Eckard, BSE, Karthik Ganesan, BS, Xiao Tang, MS, Kira Wang, BA, Brittany Wong, BS, Mark Draelos, MD, PhD, Francesco LaRocca, BS, MS, PhD, Amit Narawane, BSE, Qitong Gao, MS, Isaac Bleicher, MD, Pujan Patel, BS, Jay Rathinavelu, BSE, Kai Seely, MD, MHS, Mason Seely, BS, Maureen G. Maguire, PhD, Gui-Shuang Ying, PhD, Brendan McGeehan, MS, Joshua Shimony, MD, PhD, Dimitrios Alexopoulos, MS, Sydney Kaplan, BS, Jeanette Kenley, BS, Kayla Hannon, BS, Brian P. Smith, MD, MPH, MHS, Michael O’Shea, MD, MPH, Subashri Kurgatt, PhD, Daniel X. Hammer, PhD, William Good, MD.

Publikováno v: Ophthalmology Science, Vol 4, Iss 1, Pp 100359- (2024)

Purpose: To characterize changes in subfoveal choroidal thickness in preterm infants from 30 to 60 weeks' postmenstrual age (PMA). Design: The prospective, observational Study of Eye Imaging in Preterm infantS (BabySTEPS) enrolled infants eligible fo

Externí odkaz: https://doaj.org/article/c16a06c64ae24db98852f5b0c35f88a4

Persistent Dark Cones in Oligocone Trichromacy Revealed by Multimodal Adaptive Optics Ophthalmoscopy

Autor: Joanne Li, Tao Liu, Oliver J. Flynn, Amy Turriff, Zhuolin Liu, Ehsan Ullah, Jianfei Liu, Alfredo Dubra, Mary A. Johnson, Brian P. Brooks, Robert B. Hufnagel, Daniel X. Hammer, Laryssa A. Huryn, Brett G. Jeffrey, Johnny Tam

Publikováno v: Frontiers in Aging Neuroscience, Vol 13 (2021)

Dark cone photoreceptors, defined as those with diminished or absent reflectivity when observed with adaptive optics (AO) ophthalmoscopy, are increasingly reported in retinal disorders. However, their structural and functional impact remain unclear.

Externí odkaz: https://doaj.org/article/d2b4053401d44236a0a22e03905cf2a9

Novel Application of Long Short-Term Memory Network for 3D to 2D Retinal Vessel Segmentation in Adaptive Optics—Optical Coherence Tomography Volumes

Autor: Christopher T. Le, Dongyi Wang, Ricardo Villanueva, Zhuolin Liu, Daniel X. Hammer, Yang Tao, Osamah J. Saeedi

Publikováno v: Applied Sciences, Vol 11, Iss 20, p 9475 (2021)

Adaptive optics—optical coherence tomography (AO-OCT) is a non-invasive technique for imaging retinal vascular and structural features at cellular-level resolution. Whereas retinal blood vessel density is an important biomarker for ocular diseases,

Externí odkaz: https://doaj.org/article/12f90cbe5af24243a2593efd36545ec8