Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Daniel Wirth"'
Autor:
Evi Zhuleku, Daniel Wirth, Riikka Nissinen, Ivana Bravatà, Despina Ziavra, Andreas Duva, Jennifer Lee, Andreas Fuchs, Sabrina Mueller, Thomas Wilke, Bernd Bokemeyer
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: Biologic agents have demonstrated efficacy in treating ulcerative colitis (UC); however, treatment failure to tumor necrosis factor inhibitors (TNFi) is common in the real world. Data on preferential sequencing in clinical practice after
Externí odkaz:
https://doaj.org/article/923a4f29de8c4ad8a273786a224eee04
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Signaling bias is the ability of a receptor to differentially activate downstream signaling pathways in response to different ligands. Bias investigations have been hindered by inconsistent results in different cellular contexts. Here we int
Externí odkaz:
https://doaj.org/article/d4339b3021404b07876745f1d1736eaf
Autor:
Ayesha Khan, Richard Killick, Daniel Wirth, Dominique Hoogland, Kalina Hristova, Jakob P. Ulmschneider, Christopher R. King, Martin B. Ulmschneider
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 4, Pp n/a-n/a (2023)
Abstract Introduction Reducing brain levels of both soluble and insoluble forms of amyloid beta (Aβ) remains the primary goal of most therapies that target Alzheimer's disease (AD). However, no treatment has so far resulted in patient benefit, and c
Externí odkaz:
https://doaj.org/article/964ff61904ec4b6b91c1f1f545a124ba
Publikováno v:
Journal of Dermatological Treatment, Vol 33, Iss 2, Pp 976-982 (2022)
Background The fully human monoclonal antibody guselkumab is an effective treatment option for patients with moderate to severe psoriasis. Objective The objective of this study was to examine the cost per responder of guselkumab compared with other t
Externí odkaz:
https://doaj.org/article/6f9e92942dd24e0da77e65fe0f933957
Indirect costs associated with ulcerative colitis: a systematic literature review of real-world data
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background The economic burden of ulcerative colitis (UC), specifically related to indirect costs, is not extensively documented. Understanding and quantifying it is required by health care decision makers. Aim To assess the impact of indire
Externí odkaz:
https://doaj.org/article/a7e2c082a61a4b0bbaa5923b81d5971f
Publikováno v:
BMJ Open, Vol 11, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/319fc66bb3e147e1b389d5e0b5f3825f
Autor:
Andy K. H. Lim, Meor Azraai, Jeanette H. Pham, Wenye F. Looi, Daniel Wirth, Ashley S. L. Ng, Umesh Babu, Bharat Saluja
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 7, p 1534 (2021)
The use of antipsychotic medications is associated with side effects, but the occurrence of severe tachycardia (heart rate ≥ 130 per minute) is not well described. The aim of this study was to determine the frequency and strength of the association
Externí odkaz:
https://doaj.org/article/c196afa98be54dbd89c870aecdcc997d
Autor:
Jona T. Stahmeyer, Svenja Schauer, Siegbert Rossol, Hans Heinrich Wedemeyer, Daniel Wirth, Florence Bianic, Christian Krauth
Publikováno v:
Journal of Health Economics and Outcomes Research, Vol 1, Iss 3 (2013)
**Background:** About 400,000-500,000 people are infected with hepatitis C in Germany. Long-term consequences are the development of liver cirrhosis and hepatocellular carcinoma. The introduction of first generation protease inhibitors has significan
Externí odkaz:
https://doaj.org/article/033af96244f745dc8885c96be380b9e2
Publikováno v:
ChemSystemsChem. 4(5)
Lipid rafts are known as highly ordered lipid domains that are enriched in saturated lipids such as the ganglioside GM1. While lipid rafts are believed to exist in cells and to serve as signaling platforms through their enrichment in signaling compon
The activity of many membrane receptors is controlled through their lateral association into dimers or higher order oligomers. While Förster resonance energy transfer (FRET) measurements have been used extensively to characterize the stability of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b2ecc77f0c435cfc19b4f1d091c9614
https://doi.org/10.1101/2023.05.16.540587
https://doi.org/10.1101/2023.05.16.540587