Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniel W. Sved"'
Autor:
Sylvia Jacobi, Ann Radovsky, Todd Stedeford, Daniel W. Sved, Hanna Silberberg, Les Freshwater, John M. Ariano, Melissa J. Beck, Donald G. Stump, John A. Biesemeier, Marcia Hardy, Nicole R. Myers
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 92:17-35
BACKGROUND: Decabromodiphenyl ether (DecaBDE; CASRN 1163-19-5) is a flame retardant used in a variety of manufactured products. A single oral dose of 20.1 mg/kg administered to mice on postnatal day 3 has been reported to alter motor activity at 2, 4
Publikováno v:
Water Research. 31:294-300
Creosote, a mixture of polycyclic aromatic hydrocarbons (PAH), typically becomes depleted of low molecular weight compounds once in the environment. Previous studies indicated that PAH toxicity increased with increasing molecular weight up to phenant
Autor:
Morris H. Roberts, Daniel W. Sved
Publikováno v:
Water Research. 29:1169-1177
Testing the toxicity of contaminated sediments is crucial to evaluating environmental risks because hydrophobic chemicals readily sorb to particulate matter. The 96-h median lethal concentration (96-h LC 50 ) for creosote-contaminated sediments was d
Autor:
Nicole R. Myers, John M. Ariano, Melissa J. Beck, Sylvia Jacobi, John A. Biesemeier, Daniel W. Sved, Donald G. Stump, Hanna Silberberg, Todd Stedeford, Marcia Hardy, Eric S. Bodle
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 38(10)
The effects of route and vehicle on blood and milk levels of decabromodiphenyl ether (DecaBDE; CASRN 1163-19-5) were investigated in the rat to assist in the design and conduct of a developmental neurotoxicity study. Blood plasma and/or milk concentr
Autor:
Bruno Schmit, Nichole R. Myers, Sandra Murphy, Daniel W. Sved, Craig H. Farr, Motoki Shinohara, Jozef J. W. M. Mertens, Gary B. Marit, Phil L. Stetson
Publikováno v:
International journal of toxicology. 29(4)
S-111-S-WB, a mixture of perfluoro fatty acid ammonium salts (C6-C13), was administered orally to Crl:CD (SD)IGS-BR rats. Higher hepatic β-oxidation and liver weights with hepatocellular hypertrophy were present at the 0.125 and 0.6 mg/kg/d dosage.
Publikováno v:
Marine Environmental Research. 34:189-193
Hepatic microsomal ethoxyresorufin O-deethylase (EROD) activity was measured in spot, Leiostomus xanthurus, exposed in a laboratory flowthrough system to sediments contaminated with coal-tar creosote for 14 days. Mean total resolvable polycyclic arom
Autor:
Philip L. Stetson, Jeannie B. Kirkpatrick, Motoki Shinohara, Christopher P. Chengelis, Daniel W. Sved, Nichole R. Myers
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 27(3-4)
The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprague–Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent intravenou
Autor:
Scott D. Freer, Wei Bu, Philip L. Stetson, Daniel W. Sved, John B. Kurek, Robert A. Boyd, Shelly Hollar
Publikováno v:
Rapid communications in mass spectrometry : RCM. 17(21)
A liquid chromatography/mass spectrometry (LC/MS) analytical procedure, using a single column for sample clean-up, enrichment and separation, has been developed for the determination of the peptide AM336 in monkey cerebrospinal fluid (CSF). CSF sampl
Autor:
Tom O’Neill, Shelly Hollar, Wei Bu, Daniel W. Sved, Jane D. Mccarty, Philip L. Stetson, Nichole R. Myers
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 783(2)
A liquid chromatographic–tandem mass spectrometric (LC–MS–MS) method without sample pretreatment was developed and validated for determination of porphyrins in samples of canine urine. Acidified urine samples were directly injected into the LC
Autor:
Wei Bu, Scott D. Freer, Shelly M. Hollar, Philip L. Stetson, Robert A. Boyd, John B. Kurek, Daniel W. Sved
Publikováno v:
Rapid Communications in Mass Spectrometry: RCM; 11/15/2003, Vol. 17 Issue 21, p2394, 5p