Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Daniel W. Simmons"'
Autor:
Daniel W. Simmons, Ganesh Malayath, David R. Schuftan, Jingxuan Guo, Kasoorelope Oguntuyo, Ghiska Ramahdita, Yuwen Sun, Samuel D. Jordan, Mary K. Munsell, Brennan Kandalaft, Missy Pear, Stacey L. Rentschler, Nathaniel Huebsch
Publikováno v:
APL Bioengineering, Vol 8, Iss 1, Pp 016118-016118-18 (2024)
Engineered heart tissues have been created to study cardiac biology and disease in a setting that more closely mimics in vivo heart muscle than 2D monolayer culture. Previously published studies suggest that geometrically anisotropic micro-environmen
Externí odkaz:
https://doaj.org/article/d89cbf04a3fd418da954adb7e76b6d32
Publikováno v:
ACS Applied Materials & Interfaces. 15:25313-25323
Autor:
Daniel W. Simmons, David R. Schuftan, Jingxuan Guo, Kasoorelope Oguntuyo, Ghiska Ramahdita, Mary K. Munsell, Brennan Kandalaft, Missy Pear, Nathaniel Huebsch
Tissue engineered in-vitro models are an essential tool in biomedical research. Tissue geometry is a key determinant of function, but controlling geometry of micro-scale tissues remains a challenge. We developed a new double molding approach that all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a39e00a055b47bf7130d6e09620a773
https://doi.org/10.1101/2022.07.23.501265
https://doi.org/10.1101/2022.07.23.501265
Autor:
Daniel W, Simmons, Nathaniel, Huebsch
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2485
Micro-heart muscle arrays enable medium-throughput experiments to model the cardiac response to a variety of environmental and pharmaceutical effects. Here, we describe stem cell culture maintenance, methods for successful cardiac differentiation, an
Autor:
Daniel W. Simmons, Nathaniel Huebsch
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622605
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df0b225891a0d5a4ed08f76257fd4c6e
https://doi.org/10.1007/978-1-0716-2261-2_8
https://doi.org/10.1007/978-1-0716-2261-2_8
Autor:
Brennan Kandalaft, Ghiska Ramahdita, Daniel W. Simmons, Guy M. Genin, Brandon Rios, Kasoorelope Oguntuyo, Missy Pear, David Schuftan, Spencer P. Lake, Nathaniel Huebsch, Huanzhu Jiang, Mary K. Munsell, Jingxuan Guo
Publikováno v:
ACS biomaterials scienceengineering. 7(7)
Mechanical loading plays a critical role in cardiac pathophysiology. Engineered heart tissues derived from human induced pluripotent stem cells (iPSCs) allow rigorous investigations of the molecular and pathophysiological consequences of mechanical c
Autor:
Mary K. Munsell, Daniel W. Simmons, Kasoorelope Oguntuyo, Jingxuan Guo, Missy Pear, Brandon Rios, David Schuftan, Nathaniel Huebsch
Publikováno v:
Hypertension. 76
Mechanical loading (e.g. blood pressure) is a critical component of heart disease. Here, we developed a simple, scalable iPSC-derived micro heart muscle (μHM) model by grafting μHM on elastomeric substrates with different stiffnesses to simulate af