Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Daniel W. Gerlich"'
Autor:
María Sanz-Flores, Miguel Ruiz-Torres, Cristina Aguirre-Portolés, Aicha El Bakkali, Beatriz Salvador-Barberó, Carolina Villarroya-Beltri, Sagrario Ortega, Diego Megías, Daniel W. Gerlich, Mónica Álvarez-Fernández, Marcos Malumbres
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114494- (2024)
Summary: Cell cycle progression is regulated by the orderly balance between kinase and phosphatase activities. PP2A phosphatase holoenzymes containing the B55 family of regulatory B subunits function as major CDK1-counteracting phosphatases during mi
Externí odkaz:
https://doaj.org/article/77cd2f50a74c44d8a02a9ad8b144ca93
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Genome browsers facilitate integrated analysis of multiple genomics datasets yet visualize only a few regions at a time and lack statistical functions for extracting meaningful information. We present HiCognition, a visual exploration and ma
Externí odkaz:
https://doaj.org/article/64661975be9c4a6c8d955a709fa691bd
Autor:
Ronni S. Pedersen, Gopal Karemore, Thorkell Gudjonsson, Maj-Britt Rask, Beate Neumann, Jean-Karim Hériché, Rainer Pepperkok, Jan Ellenberg, Daniel W. Gerlich, Jiri Lukas, Claudia Lukas
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
DNA damage arising from replication stress is well studied, but the effect of mitotic errors on genome integrity is less understood. Here the authors knock down 47 mitotic regulators and record how they impact on DNA breakage events, providing a reso
Externí odkaz:
https://doaj.org/article/44999825db4e41e7abeaf600944f0a5b
Autor:
Maximilian W. G. Schneider, Bryan A. Gibson, Shotaro Otsuka, Maximilian F. D. Spicer, Mina Petrovic, Claudia Blaukopf, Christoph C. H. Langer, Paul Batty, Thejaswi Nagaraju, Lynda K. Doolittle, Michael K. Rosen, Daniel W. Gerlich
Publikováno v:
Nature. 609:183-190
Dividing eukaryotic cells package extremely long chromosomal DNA molecules into discrete bodies to enable microtubule-mediated transport of one genome copy to each of the newly forming daughter cells1–3. Assembly of mitotic chromosomes involves DNA
Autor:
Bryan A. Gibson, Claudia Blaukopf, Tracy Lou, Lifeng Chen, Lynda K. Doolittle, Ilya Finkelstein, Geeta J. Narlikar, Daniel W. Gerlich, Michael K. Rosen
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Nuclear DNA in eukaryotes is wrapped around histone proteins to form nucleosomes on a chromatin fiber. Dynamic folding of the chromatin fiber into loops and variations in the degree of chromatin compaction regulate essential processes such as transcr
Autor:
Michael Mitter, Zsuzsanna Takacs, Thomas Köcher, Ronald Micura, Christoph C. H. Langer, Daniel W. Gerlich
Publikováno v:
Nature Protocols. 17:1486-1517
Autor:
Felix Spira, Sara Cuylen-Haering, Shalin Mehta, Matthias Samwer, Anne Reversat, Amitabh Verma, Rudolf Oldenbourg, Michael Sixt, Daniel W Gerlich
Publikováno v:
eLife, Vol 6 (2017)
The actomyosin ring generates force to ingress the cytokinetic cleavage furrow in animal cells, yet its filament organization and the mechanism of contractility is not well understood. We quantified actin filament order in human cells using fluoresce
Externí odkaz:
https://doaj.org/article/081a6548fbaf44c69d7403d415d711cd
Autor:
Jan-Michael Peters, Wen Tang, Christoph C. H. Langer, Stefan L. Ameres, Catherina Gasser, Gregor Jessberger, Eva Neuner, Daniel W. Gerlich, Ronald Micura, Zsuzsanna Takacs, Anton Goloborodko, Charlie T. Beales, Michael Mitter
Publikováno v:
Nature
The three-dimensional organization of the genome supports regulated gene expression, recombination, DNA repair, and chromosome segregation during mitosis. Chromosome conformation capture (Hi-C)1,2 analysis has revealed a complex genomic landscape of
Autor:
Alberto Hernandez-Armendariz, Maximilian W. G. Schneider, Sara Cuylen-Haering, Daniel W. Gerlich, Mina Petrovic, Matthias Samwer, Liam J. Holt, Claudia Blaukopf
Publikováno v:
Nature
Gene expression in eukaryotes requires the effective separation of nuclear transcription and RNA processing from cytosolic translation1. This separation is achieved by the nuclear envelope, which controls the exchange of macromolecules through nuclea
Autor:
Daniel W. Gerlich, Michael K. Rosen, Geeta J. Narlikar, Ilya J. Finkelstein, Bryan A. Gibson, T. Lou, Claudia Blaukopf, Lynda K. Doolittle
SUMMARYEukaryotic nuclear DNA is wrapped around histone proteins to form nucleosomes, which further assemble to package and regulate the genome. Understanding of the physical mechanisms that contribute to higher order chromatin organization is limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::021448408550dac3ef0101a2c117969c
https://doi.org/10.1101/2021.11.22.469620
https://doi.org/10.1101/2021.11.22.469620