Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Daniel W. Bellott"'
Autor:
Adrianna K. San Roman, Helen Skaletsky, Alexander K. Godfrey, Neha V. Bokil, Levi Teitz, Isani Singh, Laura V. Blanton, Daniel W. Bellott, Tatyana Pyntikova, Julian Lange, Natalia Koutseva, Jennifer F. Hughes, Laura Brown, Sidaly Phou, Ashley Buscetta, Paul Kruszka, Nicole Banks, Amalia Dutra, Evgenia Pak, Patricia C. Lasutschinkow, Colleen Keen, Shanlee M. Davis, Angela E. Lin, Nicole R. Tartaglia, Carole Samango-Sprouse, Maximilian Muenke, David C. Page
Publikováno v:
Cell Genomics, Vol 4, Iss 1, Pp 100462- (2024)
Summary: Somatic cells of human males and females have 45 chromosomes in common, including the “active” X chromosome. In males the 46th chromosome is a Y; in females it is an “inactive” X (Xi). Through linear modeling of autosomal gene expres
Externí odkaz:
https://doaj.org/article/f7bcee4c14104a018d0e1ee125035ddd
Autor:
Jennifer F. Hughes, Helen Skaletsky, Peter K. Nicholls, Alexis Drake, Tatyana Pyntikova, Ting-Jan Cho, Daniel W. Bellott, David C. Page
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The mammalian X and Y chromosomes originated from a pair of ordinary autosomes. Over the past ~180 million years, the X and Y have become highly differentiated and now only recombine with each other within a short pseudoautosomal
Externí odkaz:
https://doaj.org/article/36f0d6bd4f974647b276c82792290331
Autor:
Adrianna K. San Roman, Alexander K. Godfrey, Helen Skaletsky, Daniel W. Bellott, Abigail F. Groff, Hannah L. Harris, Laura V. Blanton, Jennifer F. Hughes, Laura Brown, Sidaly Phou, Ashley Buscetta, Paul Kruszka, Nicole Banks, Amalia Dutra, Evgenia Pak, Patricia C. Lasutschinkow, Colleen Keen, Shanlee M. Davis, Nicole R. Tartaglia, Carole Samango-Sprouse, Maximilian Muenke, David C. Page
Publikováno v:
Cell Genomics, Vol 3, Iss 2, Pp 100259- (2023)
Summary: The “inactive” X chromosome (Xi) has been assumed to have little impact, in trans, on the “active” X (Xa). To test this, we quantified Xi and Xa gene expression in individuals with one Xa and zero to three Xis. Our linear modeling re
Externí odkaz:
https://doaj.org/article/a25725f53e0c4b88aad1b61692c510c9
Autor:
Daniel W. Bellott, Ting-Jan Cho, Emily K. Jackson, Helen Skaletsky, Jennifer F. Hughes, David C. Page
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
The reference sequence of structurally complex regions can only be obtained through a highly accurate clone-based approach that we call Single-Haplotype Iterative Mapping and Sequencing (SHIMS). In recent years, improvements to SHIMS have reduced the
Externí odkaz:
https://doaj.org/article/c160ce9fec7d463e86ac164abbb69b56
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1481-1486 (2019)
The introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven
Externí odkaz:
https://doaj.org/article/2f2e57f8ab17474796dc5a12d42d188d
Autor:
Jan E. Janečka, Brian W. Davis, Sharmila Ghosh, Nandina Paria, Pranab J. Das, Ludovic Orlando, Mikkel Schubert, Martin K. Nielsen, Tom A. E. Stout, Wesley Brashear, Gang Li, Charles D. Johnson, Richard P. Metz, Al Muatasim Al Zadjali, Charles C. Love, Dickson D. Varner, Daniel W. Bellott, William J. Murphy, Bhanu P. Chowdhary, Terje Raudsepp
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The rapidly evolving Y chromosome accumulates male-benefit genes but is often poorly characterized in many mammals. Here, the authors assemble the male specific region of the horse Y chromosome and investigate its evolution and function.
Externí odkaz:
https://doaj.org/article/0bff190c5adc4aeeadeb3b855b59bccc
Autor:
Daniel W. Bellott, David C. Page
Publikováno v:
Genome Res
Different ancestral autosomes independently evolved into sex chromosomes in snakes, birds, and mammals. In snakes and birds, females are ZW and males are ZZ; in mammals, females are XX and males are XY. Although X and Z Chromosomes retain nearly all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795030b415bee6f6df07ea492b7279a2
https://doi.org/10.1101/gr.268516.120
https://doi.org/10.1101/gr.268516.120
Autor:
Michelle A Carmell, Gregoriy A Dokshin, Helen Skaletsky, Yueh-Chiang Hu, Josien C van Wolfswinkel, Kyomi J Igarashi, Daniel W Bellott, Michael Nefedov, Peter W Reddien, George C Enders, Vladimir N Uversky, Craig C Mello, David C Page
Publikováno v:
eLife, Vol 5 (2016)
The advent of sexual reproduction and the evolution of a dedicated germline in multicellular organisms are critical landmarks in eukaryotic evolution. We report an ancient family of GCNA (germ cell nuclear antigen) proteins that arose in the earliest
Externí odkaz:
https://doaj.org/article/bb2777a7496b45ab8f0371093ab6a3f1
Autor:
Ting-Jan Cho, Jennifer F. Hughes, Donna M. Muzny, James E. Womack, Kim C. Worley, Laura G. Brown, Lucinda Fulton, Catrina Fronick, Daniel W. Bellott, Bhanu P. Chowdhary, Elaine Owens, David C. Page, Shannon Dugan-Rocha, Tina A. Graves-Lindsay, Natalia Koutseva, Terje Raudsepp, Colin Kremitzki, Tatyana Pyntikova, Ziad Khan, William J. Murphy, Helen Skaletsky, Richard A. Gibbs, Wesley C. Warren, Richard K. Wilson
Publikováno v:
Genome Research. 30:1716-1726
Studies of Y Chromosome evolution have focused primarily on gene decay, a consequence of suppression of crossing-over with the X Chromosome. Here, we provide evidence that suppression of X–Y crossing-over unleashed a second dynamic: selfish X–Y a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b6b7baf035063fb9a1606b28c937627
https://doi.org/10.1101/gr.269902.120
https://doi.org/10.1101/gr.269902.120
Autor:
Daniel W Bellott
The reference sequence of structurally complex regions can only be obtained through a highly accurate clone-based approach that we call Single-Haplotype Iterative Mapping and Sequencing (SHIMS). In recent years, improvements to SHIMS have reduced the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbbb29275d5125d95371e2e59236a225
https://doi.org/10.17504/protocols.io.b34tqqwn
https://doi.org/10.17504/protocols.io.b34tqqwn
