Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Daniel W. A. Buchan"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Intrinsically disordaered proteins (IDPs) are a prevalent phenomenon with over 30% of human proteins estimated to have long disordered regions. Computational methods are widely used to study IDPs, however, nearly all treat disorder in a bina
Externí odkaz:
https://doaj.org/article/aaef04bc9a334c4280f7d5ac3c2199e0
Autor:
Daniel W. A. Buchan, David T. Jones
Publikováno v:
Nucleic Acids Research
The PSIPRED Workbench is a web server offering a range of predictive methods to the bioscience community for 20 years. Here, we present the work we have completed to update the PSIPRED Protein Analysis Workbench and make it ready for the next 20 year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f1ae5e167098165fb30680e566db40
http://europepmc.org/articles/PMC6602445
http://europepmc.org/articles/PMC6602445
Autor:
Vaishali P, Waman, Tom L, Blundell, Daniel W A, Buchan, Julian, Gough, David, Jones, Lawrence, Kelley, Alexey, Murzin, Arun Prasad, Pandurangan, Ian, Sillitoe, Michael, Sternberg, Pedro, Torres, Christine, Orengo
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2165
Genome3D consortium is a collaborative project involving protein structure prediction and annotation resources developed by six world-leading structural bioinformatics groups, based in the United Kingdom (namely Blundell, Murzin, Gough, Sternberg, Or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38644a059a07b29345ec641f57ed6415
https://pubmed.ncbi.nlm.nih.gov/32621218
https://pubmed.ncbi.nlm.nih.gov/32621218
Autor:
Christine A. Orengo, Lawrence A. Kelley, Daniel W. A. Buchan, Gustavo A. Salazar, Julian Gough, Michael J.E. Sternberg, Tom L. Blundell, Arun Prasad Pandurangan, Robert D. Finn, Antonina Andreeva, Sameer Velankar, Alexey G. Murzin, Su Datt Lam, Marcin J. Skwark, Ian Sillitoe, Typhaine Paysan-Lafosse, David T. Jones
Publikováno v:
D319
D314
Nucleic Acids Research
D314
Nucleic Acids Research
Genome3D (https://www.genome3d.eu) is a freely available resource that provides consensus structural annotations for representative protein sequences taken from a selection of model organisms. Since the last NAR update in 2015, the method of data sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e3ebfe8b7a884b400d5854b5316527
https://www.repository.cam.ac.uk/handle/1810/318687
https://www.repository.cam.ac.uk/handle/1810/318687
Autor:
Ian Sillitoe, Michael J.E. Sternberg, Tom L. Blundell, Julian Gough, David T. Jones, Daniel W. A. Buchan, Arun Prasad Pandurangan, Alexey G. Murzin, Pedro Henrique Monteiro Torres, Christine A. Orengo, Vaishali P Waman, Lawrence A. Kelley
Publikováno v:
Methods in Molecular Biology ISBN: 9781071607077
Genome3D consortium is a collaborative project involving protein structure prediction and annotation resources developed by six world-leading structural bioinformatics groups, based in the United Kingdom (namely Blundell, Murzin, Gough, Sternberg, Or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d5c655e9d3bd3f159545c02dfd45a8d
https://doi.org/10.1007/978-1-0716-0708-4_3
https://doi.org/10.1007/978-1-0716-0708-4_3
Autor:
Daniel W. A. Buchan, David T. Jones
Publikováno v:
ProteinsREFERENCES. 88(4)
In this paper, using Word2vec, a widely-used natural language processing method, we demonstrate that protein domains may have a learnable implicit semantic "meaning" in the context of their functional contributions to the multi-domain proteins in whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93f7712a8d848018da63952c1cfe4af
https://pubmed.ncbi.nlm.nih.gov/31703152
https://pubmed.ncbi.nlm.nih.gov/31703152
Autor:
Daniel W A, Buchan, David T, Jones
Publikováno v:
Bioinformatics
Motivation: Protein fold recognition when appropriate, evolutionarily-related, structural templates can be identified is often trivial and may even be viewed as a solved problem. However in cases where no homologous structural templates can be detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2427f17a0e708020f0b2c5ba057d5df
https://pubmed.ncbi.nlm.nih.gov/28419258
https://pubmed.ncbi.nlm.nih.gov/28419258
Autor:
Christine A. Orengo, Adrian J. Shepherd, James E. Bray, Frances M. G. Pearl, Daniel W. A. Buchan, David A. Lee
Publikováno v:
Protein Science. 11:233-244
An automatic sequence search and analysis protocol (DomainFinder) based on PSI-BLAST and IMPALA, and using conservative thresholds, has been developed for reliably integrating gene sequences from GenBank into their respective structural families with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f470236a4e53311d72630b12f4bf8a54
https://doi.org/10.1110/ps.16802
https://doi.org/10.1110/ps.16802
Autor:
Tony E, Lewis, Ian, Sillitoe, Antonina, Andreeva, Tom L, Blundell, Daniel W A, Buchan, Cyrus, Chothia, Domenico, Cozzetto, José M, Dana, Ioannis, Filippis, Julian, Gough, David T, Jones, Lawrence A, Kelley, Gerard J, Kleywegt, Federico, Minneci, Jaina, Mistry, Alexey G, Murzin, Bernardo, Ochoa-Montaño, Matt E, Oates, Marco, Punta, Owen J L, Rackham, Jonathan, Stahlhacke, Michael J E, Sternberg, Sameer, Velankar, Christine, Orengo
Publikováno v:
Nucleic Acids Research
Genome3D (http://www.genome3d.eu) is a collaborative resource that provides predicted domain annotations and structural models for key sequences. Since introducing Genome3D in a previous NAR paper, we have substantially extended and improved the reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84cea9bbe237edc76a5077743447ee0
https://www.repository.cam.ac.uk/handle/1810/318731
https://www.repository.cam.ac.uk/handle/1810/318731
Publikováno v:
Current Opinion in Structural Biology. 13:359-369
Protein translations of over 100 complete genomes are now available. About half of these sequences can be provided with structural annotation, thereby enabling some profound insights into protein and pathway evolution. Whereas the major domain struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb8a136f13a119b24ba57b3a9fa033f
https://doi.org/10.1016/s0959-440x(03)00079-4
https://doi.org/10.1016/s0959-440x(03)00079-4