Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Daniel W Wheeler"'
Autor:
Rebecca Fisher, Judith Ewing, Alice Garrett, E Katherine Harrison, Kimberly KT Lwin, Daniel W Wheeler
Publikováno v:
F1000Research, Vol 2 (2013)
Background: Homeless people are known to suffer disproportionately with health problems that reduce physical functioning and quality of life, and shorten life expectancy. They suffer from a wide range of diseases that are known to be painful, but lit
Externí odkaz:
https://doaj.org/article/3e20befe6fac478bbe737e903915c114
Autor:
Daniel W Wheeler, Andrew J Thompson, Federico Corletto, Jill Reckless, Justin C T Loke, Nicolas Lapaque, Andrew J Grant, Pietro Mastroeni, David J Grainger, Claire L Padgett, John A O'Brien, Nigel G A Miller, John Trowsdale, Sarah C R Lummis, David K Menon, John S Beech
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17152 (2011)
GABA(A) receptors are members of the Cys-loop family of neurotransmitter receptors, proteins which are responsible for fast synaptic transmission, and are the site of action of wide range of drugs. Recent work has shown that Cys-loop receptors are pr
Externí odkaz:
https://doaj.org/article/23173b15fc8b4b9690a691153a3c3a03
Autor:
Simon Bond, David K. Menon, Michael C. Lee, Graham Armstrong, Daniel W. Wheeler, Ingrid Scholtes, Peter A. McNaughton
Publikováno v:
Lee, M C, Bond, S, Wheeler, D, Scholtes, I, Armstrong, G, McNaughton, P & Menon, D 2019, ' A randomised, double-blind, placebo-controlled crossover trial of the influence of the HCN channel blocker ivabradine in a healthy volunteer pain model : an enriched population trial ', Pain, vol. 160, no. 11, pp. 2554-2565 . https://doi.org/10.1097/j.pain.0000000000001638
Preclinical studies suggest that type 2 hyperpolarization-activated cyclic nucleotide gated ion channels (HCN2) are necessary for neuropathic pain. This trial assessed the influence of ivabradine, a nonselective HCN channel blocker, on capsaicin-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882f00ce870f2564d95a8a0a2cf71d33
https://doi.org/10.1097/j.pain.0000000000001638
https://doi.org/10.1097/j.pain.0000000000001638
Autor:
David K. Menon, Van B. Lu, Frank Reimann, Christopher A. Brown, Daniel W. Wheeler, Michael C. Lee, Gerard Callejo, James R.F. Hockley, C. Geoffrey Woods, Emily V. Fletcher, Michael S. Nahorski, Luke A. Pattison, Ichrak Drissi, Patrik Ernfors, Kaitlin Stouffer, Gillian Ison, Ewan St. John Smith
Publikováno v:
CELL REPORTS
Cell Reports
Cell Reports
Summary By studying healthy women who do not request analgesia during their first delivery, we investigate genetic effects on labor pain. Such women have normal sensory and psychometric test results, except for significantly higher cuff pressure pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c065c50f304e81604ab566092d75803a
http://livrepository.liverpool.ac.uk/3090310/1/Cell_Reports_2020.pdf
http://livrepository.liverpool.ac.uk/3090310/1/Cell_Reports_2020.pdf
Autor:
Ewan St. John Smith, Patrik Ernfors, David K. Menon, Frank Reimann, Geoffrey Woods, Kaitlin Stouffer, Michael S. Nahorski, Emily V. Fletcher, Van B. Lu, Daniel W. Wheeler, Christopher A. Brown, Ichrak Drissi, James R.F. Hockley, Gill Ison, Michael C. Lee, Luke A. Pattison, Gerard Callejo
Publikováno v:
SSRN Electronic Journal.
We sought genetic effects on labour pain by studying healthy women who did not request analgesia during their first delivery. Extensive sensory and psychometric testing were normal in these women, except for significantly higher cuff-pressure pain. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1d9b110bb09838511abb1cfc9c0b7e5
https://doi.org/10.2139/ssrn.3553404
https://doi.org/10.2139/ssrn.3553404
Autor:
Anjalee Brahmbhatt, Tope Adeloye, Ari Ercole, Steven M. Bishop, Helen L. Smith, Daniel W. Wheeler
Publikováno v:
Pediatric Reports, Vol 4, Iss 1, Pp e10-e10 (2012)
Pain assessment in children can be extremely challenging. Most professional bodies recommend that parents or carers should be involved with their child’s pain assessment; but the evidence that parents can accurately report pain on behalf of their c
Externí odkaz:
https://doaj.org/article/26564a614b56477d88b81f01504c2648
Publikováno v:
The Department Chair. 30:1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d74b484052eca9b65ef3a47bf0c49bf
https://doi.org/10.1002/dch.30262
https://doi.org/10.1002/dch.30262
Autor:
Ravi Mahajan, Alan Merry, Jennifer Weller, Jane Torrie, Craig Webster, Rachel Evley, Chris Frampton, Arun Kumar Gupta, Jacqueline A. Hannam, Daniel W. Wheeler, Kylie-Ellen Edwards
Publikováno v:
Anesthesiology. 126:472-481
Background Simulation has been used to investigate clinical questions in anesthesia, surgery, and related disciplines, but there are few data demonstrating that results apply to clinical settings. We asked “would results of a simulation-based study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd028cc22fa81fc506cf75acc8df2d6
https://doi.org/10.1097/aln.0000000000001514
https://doi.org/10.1097/aln.0000000000001514
Autor:
Daniel W. Wheeler
Publikováno v:
The Department Chair. 30:28-29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24f9a5dcd9f3121090bf669eaa9b409b
https://doi.org/10.1002/dch.30306
https://doi.org/10.1002/dch.30306
Autor:
Michael C. Lee, Vaithianadan Mani, Daniel W. Wheeler, Andrew Bell, Y Boyle, David K. Menon, Anuj Bhatia, Sara Kinna, Boris A. Chizh
Cutaneous mechanical hyperalgesia can be induced in healthy volunteers in early phase analgesic studies to model central sensitization, a key mechanism of persistent pain. However, such hyperalgesia is short-lived (a matter of hours), and is used onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fded513fa8e428f5815d319daf42ae36
https://www.repository.cam.ac.uk/handle/1810/291609
https://www.repository.cam.ac.uk/handle/1810/291609