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of 6
pro vyhledávání: '"Daniel W Serber"'
Autor:
Daniel W Serber, Allison Rogala, Maisam Makarem, Gary B Rosson, Karl Simin, Virginia Godfrey, Terry Van Dyke, Connie J Eaves, Scott J Bultman
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31346 (2012)
The BRG1 catalytic subunit of SWI/SNF-related complexes is required for mammalian development as exemplified by the early embryonic lethality of Brg1 null homozygous mice. BRG1 is also a tumor suppressor and, in mice, 10% of heterozygous (Brg1(null/+
Externí odkaz:
https://doaj.org/article/489315340d2f4253a20c5efede80de1c
Autor:
Daniel W. Serber, Vonn Walter, Christoph Plass, Bernard E. Weissman, D. Neil Hayes, Jiren Zhang, Christopher Bartlett, Yanfang Zheng, Ying Li, Shujie Song, Christopher D. Sproul, Dominic J. Smiraglia, Mehmet Karaca
Publikováno v:
Molecular Cancer Research. 12:560-570
The SWI/SNF chromatin-remodeling complex regulates gene expression and alters chromatin structures in an ATP-dependent manner. Recent sequencing efforts have shown mutations in BRG1 (SMARCA4), one of two mutually exclusive ATPase subunits in the comp
Autor:
Ronald L. Chandler, Terry Magnuson, Daniel W. Serber, J. Brennan, Jonathan C. Schisler, Cam Patterson
Publikováno v:
Molecular and Cellular Biology. 33:265-280
Every known SWI/SNF chromatin-remodeling complex incorporates an ARID DNA binding domain-containing subunit. Despite being a ubiquitous component of the complex, physiological roles for this domain remain undefined. Here, we show that disruption of A
Publikováno v:
Biology of Reproduction. 94
The ability to faithfully transmit genetic information across generations via the germ cells is a critical aspect of mammalian reproduction. The process of germ cell development requires a number of large-scale modulations of chromatin within the nuc
Autor:
John P. Didion, Terry Magnuson, Jonathan C. Schisler, David B. Darr, Della Yee, William Y. Kim, Joshua Starmer, Fernando Pardo-Manuel de Villena, Ronald L. Chandler, Daniel W. Serber, Matthew D. Wilkerson, Jeffrey S. Damrauer, Jesse R. Raab, Jessie Xiong
Publikováno v:
Nature communications
Ovarian clear-cell carcinoma (OCCC) is an aggressive form of ovarian cancer with high ARID1A mutation rates. Here we present a mutant mouse model of OCCC. We find that ARID1A inactivation is not sufficient for tumour formation, but requires concurren
Autor:
Connie J. Eaves, Allison R. Rogala, Daniel W. Serber, Virginia Godfrey, Gary B. Rosson, Scott J. Bultman, Maisam Makarem, Karl Simin, Terry Van Dyke
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31346 (2012)
PLoS ONE
PLoS ONE
The BRG1 catalytic subunit of SWI/SNF-related complexes is required for mammalian development as exemplified by the early embryonic lethality of Brg1 null homozygous mice. BRG1 is also a tumor suppressor and, in mice, 10% of heterozygous (Brg1(null/+