Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Daniel W Carr"'
Autor:
Jeffrey W Streb, Xiaochun Long, Ting-Hein Lee, Qiang Sun, Chad M Kitchen, Mary A Georger, Orazio J Slivano, William S Blaner, Daniel W Carr, Irwin H Gelman, Joseph M Miano
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18538 (2011)
Retinoids are used clinically to treat a number of hyper-proliferative disorders and have been shown in experimental animals to attenuate vascular occlusive diseases, presumably through nuclear receptors bound to retinoic acid response elements (RARE
Externí odkaz:
https://doaj.org/article/140e7afc289a4e2198d80a2ce8f33b11
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Abnormal regulation of the inflammatory response is an important component of diseases such as diabetes, Alzheimer's disease and multiple sclerosis (MS). Lipoic acid (LA) has been shown to have antioxidant and anti-inflammatory properties and is bein
Externí odkaz:
https://doaj.org/article/bf2a664783f04089be103be94b1ef983
Autor:
Robynn V Schillace, Casey L Miller, Neal Pisenti, Jeff E Grotzke, Gwendolyn M Swarbrick, David M Lewinsohn, Daniel W Carr
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4807 (2009)
BACKGROUND: Dendritic cells (DC) are the most potent antigen presenting cells (APC) of the immune system. Prostaglandin E(2), cyclic AMP, and protein kinase A (PKA) have all been shown to regulate DC maturation and activity. In other cells, the abili
Externí odkaz:
https://doaj.org/article/68c4b5d89bde4720ae0c76ca86cbacca
Autor:
Eric Griffiths, Jae Dugan, Paige Snow, Brieanna Brown, Ellen Lee, Daniel W. Carr, Carlos D. Rose, Holly L. Rosenzweig, James T. Rosenbaum, Michael P. Davey
Publikováno v:
The Journal of Immunology. 194:349-357
The biochemical mechanism by which mutations in nucleotide-binding oligomerization domain containing 2 (NOD2) cause Blau syndrome is unknown. Several studies have examined the effect of mutations associated with Blau syndrome in vitro, but none has l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2012a28de04bf922fb37e6a1b1eed42
https://doi.org/10.4049/jimmunol.1402330
https://doi.org/10.4049/jimmunol.1402330
Publikováno v:
Molecular Immunology. 53:173-178
α-Tocopherol, the most biologically active member of the vitamin E family of fat soluble compounds, exhibits both antioxidant and anti-inflammatory properties. However, its mechanisms of action are not fully understood. Here, we show that, unlike ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477b865938832bf8fefa5466f1caa085
https://doi.org/10.1016/j.molimm.2012.08.005
https://doi.org/10.1016/j.molimm.2012.08.005
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Two type II regulatory (R) subunits of cAMP-dependent protein kinase (PKA) of 50 and 47 kDa have been identified in Aplysia neurons by several criteria which include phosphorylation by the catalytic subunit of PKA and nanomolar affinity for a peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a91c00dee71a7deb2b9070074918666
https://ora.ox.ac.uk/objects/uuid:e07f7b74-c61a-4409-8e24-31993a270176
https://ora.ox.ac.uk/objects/uuid:e07f7b74-c61a-4409-8e24-31993a270176
Autor:
Daniel W. Carr, Maxfield P. Flynn, Mary Hunzicker-Dunn, Evelyn T. Maizels, Sarah E. Fiedler, Amelia B. Karlsson
Publikováno v:
Journal of Cell Science.
Preovulatory granulosa cells express the low-molecular-mass MAP2D variant of microtubule-associated protein 2 (MAP2). Activation of the luteinizing hormone choriogonadotropin receptor by human choriogonadotropin (hCG) promotes dephosphorylation of MA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d7b9a158e5892c99587ce5b97b0cde
https://doi.org/10.1242/jcs.190397
https://doi.org/10.1242/jcs.190397
Autor:
John W. Regan, Sonemany Salinthone, Dennis Bourdette, Robynn V. Schillace, Daniel W. Carr, Catherine Tsang
Publikováno v:
The Journal of Nutritional Biochemistry. 22:681-690
Lipoic acid (LA) is a naturally occurring fatty acid that exhibits anti-oxidant and anti-inflammatory properties and is being pursued as a therapeutic for many diseases including multiple sclerosis, diabetic polyneuropathy and Alzheimer's disease. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0282a9df1380c8c04da4ce12d90e61bb
https://doi.org/10.1016/j.jnutbio.2010.05.008
https://doi.org/10.1016/j.jnutbio.2010.05.008
Publikováno v:
Journal of Neuroimmunology. 199:46-55
The antioxidant lipoic acid (LA) treats and prevents the animal model of multiple sclerosis (MS), experimental autoimmune encephalomyelitis (EAE). In an effort to understand the therapeutic potential of LA in MS, we sought to define the cellular mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d092f541fff0122f5f38ee0d01710c9e
https://doi.org/10.1016/j.jneuroim.2008.05.003
https://doi.org/10.1016/j.jneuroim.2008.05.003
Publikováno v:
Biology of Reproduction. 78:184-192
In somatic cells, RHOA mediates actin dynamics through a GNA13-mediated signaling cascade involving RHO kinase (ROCK), LIM kinase (LIMK), and cofilin. RHOA can be negatively regulated by protein kinase A (PRKA), and it interacts with members of the A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287a93456f1722e4ccc690ccfef5d028
https://doi.org/10.1095/biolreprod.107.062943
https://doi.org/10.1095/biolreprod.107.062943