Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Daniel Vyoral"'
Autor:
Ajay Singh, Maradumane L Mohan, Alfred Orina Isaac, Xiu Luo, Jiri Petrak, Daniel Vyoral, Neena Singh
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4468 (2009)
Converging evidence leaves little doubt that a change in the conformation of prion protein (PrP(C)) from a mainly alpha-helical to a beta-sheet rich PrP-scrapie (PrP(Sc)) form is the main event responsible for prion disease associated neurotoxicity.
Externí odkaz:
https://doaj.org/article/f4de2420f1024f8a86e36d88ddeb7846
Autor:
Ajay Singh, Maradumane L. Mohan, Alfred Orina Isaac, Xiu Luo, Jiri Petrak, Daniel Vyoral, Neena Singh
Publikováno v:
PLoS ONE, Vol 4, Iss 2 (2009)
Externí odkaz:
https://doaj.org/article/c09c24432fbf492285ecdab934bb5c3a
Autor:
Tereza Hrdinova, Ondrej Toman, Jiri Dresler, Jana Klimentova, Barbora Salovska, Petr Pajer, Oldrich Bartos, Vaclava Polivkova, Jana Linhartova, Katerina Machova Polakova, Hana Kabickova, Barbora Brodska, Matyas Krijt, Jan Zivny, Daniel Vyoral, Jiri Petrak
Publikováno v:
International Journal of Oncology. 58:238-250
Chronic myeloid leukemia (CML) is a malignant hematopoietic disorder distinguished by the presence of a BCR‑ABL1 fused oncogene with constitutive kinase activity. Targeted CML therapy by specific tyrosine kinase inhibitors (TKIs) leads to a marked
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1862:2895-2901
Dysregulated iron metabolism has a detrimental effect on cardiac function. The importance of iron homeostasis in cardiac health and disease warrants detailed studies of cardiomyocyte iron uptake, utilization and recycling at the molecular level. In t
Autor:
Daniel Vyoral, Jiri Petrak
Publikováno v:
Pharmacological Research. 115:242-254
Iron is an essential biogenic element for both prokaryotic and eukaryotic cells. In humans iron is present in hundreds of different metalloproteins. The peptide hormone hepcidin serves as a master regulator of iron homeostasis on the level of single
Autor:
Matyas Krijt, Emmanuel Lesuisse, Thibaut Léger, Jean-Michel Camadro, Ronald Malych, Jan Mach, Eva Kotabová, Daniel Vyoral, Ivo Florin Scheiber, Jana Pilátová, Robert Sutak, Ondřej Prášil
Publikováno v:
Metallomics
Metallomics, Royal Society of Chemistry, 2019, 11 (10), pp.1657-1666. ⟨10.1039/c9mt00078j⟩
Metallomics, Royal Society of Chemistry, 2019, 11 (10), pp.1657-1666. ⟨10.1039/c9mt00078j⟩
International audience; Iron and copper are essential elements for practically all living organisms. Their metabolism is frequently interconnected, and while copper is relatively abundant in the ocean, iron is often a limiting factor for the growth o
Autor:
Tereza Havlenova, Daniel Vyoral, Vojtech Melenovsky, Matyas Krijt, Tomáš Pluháček, Matej Behounek, Jiri Petrak, Ludek Cervenka, Janka Franeková
Publikováno v:
Biochimica et biophysica acta. General subjects. 1863(4)
Background Up to 50% of patients with chronic heart failure (HF) have systemic iron deficiency, which contributes to symptoms and poor prognosis. Myocardial iron deficiency (MID) in HF patients has been recently documented, but its causes and consequ
Autor:
Ondrej Toman, Daniel Vyoral, K. Machova Polakova, Jana Linhartova, Jiri Petrak, Radovan Fišer, Jan Zach, Ondrej Vit, T. Kabickova
Publikováno v:
Oncology Reports
Chronic myeloid leukemia (CML) therapy has markedly improved patient prognosis after introduction of imatinib mesylate for clinical use. However, a subset of patients develops resistance to imatinib and other tyrosine kinase inhibitors (TKIs), mainly
Autor:
Jana Cmejlova, Jan Zivny, Radek Cmejla, Robert Ivanek, Jiri Petrak, Chris D. Vulpe, Daniel Vyoral, Ondrej Toman
Publikováno v:
PROTEOMICS. 8:1744-1749
After reading many 2-DE-based articles featuring lists of the differentially expressed proteins, one starts experiencing a disturbing déjà vu. The same proteins seem to predominate regardless of the experiment, tissue or species. To quantify the oc
Autor:
Xiangcong Xu, Robert Sutak, Mohammed Abul Kashem, Megan Whitnall, Des R. Richardson, Daniel Vyoral
Publikováno v:
PROTEOMICS. 8:1731-1741
A frequent cause of death in Friedreich's ataxia patients is cardiomyopathy, but the molecular alterations underlying this condition are unknown. We performed 2-DE to characterize the changes in protein expression of hearts using the muscle creatine