Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Daniel Verdon"'
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62753 (2013)
The study of melanocyte biology is important to understand their role in health and disease. However, current methods of gene transfer into melanocytes are limited by safety or efficacy. Recombinant adeno-associated virus (rAAV) has been extensively
Externí odkaz:
https://doaj.org/article/e972f4073f5643dea0cd96d0ba80ba96
Autor:
Anh Hoa Nguyen, Christian Schwabe, G. Mani Subramanian, Daniel Verdon, P. Rod Dunbar, Anna E. S. Brooks, Edward Gane, Anuj Gaggar
Publikováno v:
Journal of Hepatology. 71:900-907
Background & Aims To evaluate the hypothesis that increasing T cell frequency and activity may provide durable control of hepatitis B virus (HBV), we administered nivolumab, a programmed death receptor 1 (PD-1) inhibitor, with or without GS-4774, an
Autor:
Misty R. Jenkins, Daniel Verdon
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4245, p 4245 (2021)
Cancers, Vol 13, Iss 4245, p 4245 (2021)
Simple Summary Cancerous cells acquire genetic mutations that can lead to changes in the amino acid sequence of proteins. These altered amino acid sequences, or “neoantigens” allow the immune system to recognize the mutated cells as “non-self
Autor:
Hannah E. Hughes-Parry, Ben R Kiefel, Kylie Luong, Katherine A. Watson, Ryan S. Cross, Fiona M Gracey, Daniel Verdon, Lucy C. Sullivan, Matthias Mulazzani, Rebecca C. Abbott, Colleen D'Arcy, Misty R. Jenkins, Melinda Iliopoulos
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 7, Pp n/a-n/a (2021)
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 5, Pp n/a-n/a (2021)
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 5, Pp n/a-n/a (2021)
Objectives The increasing success of Chimeric Antigen Receptor (CAR) T cell therapy in haematological malignancies is reinvigorating its application in many other cancer types and with renewed focus on its application to solid tumors. We present a no
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 7357, p 7357 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 7357, p 7357 (2020)
T cells follow a triphasic distinct pathway of activation, proliferation and differentiation before becoming functionally and phenotypically ‘exhausted’ in settings of chronic infection, autoimmunity and in cancer. Exhausted T cells progressively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f96669405cc43f4da5a3e0c4e1cfd6e
https://doi.org/10.20944/preprints202008.0728.v1
https://doi.org/10.20944/preprints202008.0728.v1
Publikováno v:
Journal of medicinal chemistry. 63(5)
Cancer immunotherapy has gained increasing attention due to its potential specificity and lack of adverse side effects when compared to more traditional modes of treatment. Toll-like receptor 2 (TLR2) agonists are lipopeptides possessing the S-[2,3-b
Autor:
Martin Middleditch, E. Scott Graham, Nigel P. Birch, P. Rod Dunbar, Evert Jan Loef, Daniel Verdon, Anna E. S. Brooks, Inken D. Kelch, Natalie Lorenz, David R. Greenwood, Moyra M. Black
Publikováno v:
Immunology and cell biology. 94(10)
The homeostatic chemokine CCL21 has a pivotal role in lymphocyte homing and compartment localisation within the lymph node, and also affects adhesion between immune cells. The effects of CCL21 are modulated by its mode of presentation, with different
Publikováno v:
Tissue and Cell. 39:35-46
The cellular distributions of the growth factors FGF-2 and VEGF, and their receptors FGFR1, FGFR2 and FGFR3, and VEGFR-2 respectively, were visualized by immunohistochemistry and light microscopy in sections of growing red deer antler. Both of these
Autor:
Stefanie Papst, Vaughan Feisst, Margaret A. Brimble, Daniel Verdon, David E. Williams, Clive W. Evans, P. Rod Dunbar, Richard D. Tilley
Publikováno v:
Organicbiomolecular chemistry. 13(23)
Herein, we report the facile preparation of cell-targeted platinum nanoparticles (PtNPs), through the design of peptides that, as a single molecule added in small concentration during the synthesis, control the size of PtNP clusters during their grow
Autor:
P. Rod Dunbar, Natalie Lorenz, Anna E. S. Brooks, Daniel Verdon, Chun-Jen J. Chen, Claudia Mansell, Catherine E. Angel, Nigel P. Birch, Evert Jan Loef
Publikováno v:
Journal of leukocyte biology. 97(4)
Contact between T cells and APCs and activation of an effective immune response trigger cellular polarization and the formation of a structured interface known as the immunological synapse. Interactions across the synapse and secretion of T cell and