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pro vyhledávání: '"Daniel Termine"'
Autor:
Thibaut Imberdis, Frank Soldner, Michel Becuwe, Sepp D. Kohlwein, Yelena Freyzon, Gary P.H. Ho, Aftabul Haque, Tobias C. Walther, Clary B. Clish, Elizabeth Terry-Kantor, Dennis J. Selkoe, Saranna Fanning, Gregory A. Newby, Daniel Termine, Tallie Noble, Nagendran Ramalingam, M. Inmaculada Barrasa, Robert V. Farese, Michael A. Welte, Susan Lindquist, Yali Lou, Jackson Sandoe, Tae-Eun Kim, Harald F. Hofbauer, Silke Nuber, David Pincus, Dirk Landgraf, Rudolf Jaenisch, Supriya Srinivasan, Ulf Dettmer, Valeriya Baru
Publikováno v:
PMC
In Parkinson's disease (PD), α-synuclein (αS) pathologically impacts the brain, a highly lipid-rich organ. We investigated how alterations in αS or lipid/fatty acid homeostasis affect each other. Lipidomic profiling of human αS-expressing yeast r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995be04b05c6e841478eda306d3ad6bc
https://hdl.handle.net/1721.1/125128
https://hdl.handle.net/1721.1/125128
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(8)
Synucleinopathies are neurodegenerative diseases associated with toxicity of the lipid-binding protein α-synuclein (α-syn). When expressed in yeast, α-syn associates with membranes at the endoplasmic reticulum and traffics with vesicles out to the