Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Daniel T. Organisciak"'
Autor:
Ruth M. Darrow, Rekha Rangarajan, Alison Ziesel, John C. Lang, Paul Wong, Daniel T. Organisciak, Christine M. Rapp
Publikováno v:
Photochemistry and Photobiology. 88:1396-1407
Mineral supplements are often included in multivitamin preparations because of their beneficial effects on metabolism. In this study, we used an animal model of light-induced retinal degeneration to test for photoreceptor cell protection by the essen
Autor:
Daniel T. Organisciak, D.K. Vaughan
Publikováno v:
Progress in Retinal and Eye Research. 29:113-134
By its action on rhodopsin, light triggers the well-known visual transduction cascade, but can also induce cell damage and death through phototoxic mechanisms -- a comprehensive understanding of which is still elusive despite more than 40 years of re
Publikováno v:
Photochemistry and Photobiology. 75:547-553
This study investigated a possible circadian rhythm of light damage susceptibility in photoreceptors of both cyclic light-reared and dark-reared rats. A single exposure to intense green light was administered, beginning either in the early light peri
Autor:
Daniel T. Organisciak, Stanley A Hazen, Ruth M. Darrow, Silvia C. Finnemann, George Hoppe, Maria Febbraio, Roy L. Silverstein, Eugene A. Podrez, Robert G. Salomon, Mingjiang Sun, Suresh P. Annangudi, Lian Shan
Publikováno v:
Journal of Biological Chemistry. 281:4222-4230
Clearance by the retinal pigment epithelium (RPE) of shed photoreceptor outer segments (OSs), a tissue with one of the highest turnover rates in the body, is critical to the maintenance and normal function of the retina. We hypothesized that there is
Autor:
Dennis J. Stuehr, Lin Yan, John W. Crabb, Kulwant S. Aulak, K.A. West, Daniel T. Organisciak, Hirokazu Sakaguchi, Joe G. Hollyfield, Ruth M. Darrow, Masaru Miyagi
Publikováno v:
Molecular & Cellular Proteomics. 1:293-303
As part of ongoing efforts to better understand the role of protein oxidative modifications in retinal pathology, protein nitration in retina has been compared between rats exposed to damaging light or maintained in the dark. In the course of the res
Publikováno v:
The Retina and Circadian Rhythms ISBN: 9781461496120
Light-induced retinal damage has long served as a model of retinal dysfunction and visual cell loss arising from inherited disease or caused by oxidative stress. Its utility resides in the fact that nearly the entire complement of retinal photorecept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6506b71a655f90b7091a3550daca4171
https://doi.org/10.1007/978-1-4614-9613-7_8
https://doi.org/10.1007/978-1-4614-9613-7_8
Publikováno v:
Photochemistry and Photobiology. 70:261-268
In the rat, photoreceptor cell death from exposure to intense visible light can be prevented by prior treatment with antioxidants. In this study we subjected albino rats raised in dim cyclic light and rats made more susceptible to light damage by rea
Publikováno v:
Photochemistry and Photobiology. 69:91-98
— Intense visible light can damage retinal photoreceptor cells by photochemical or thermal processes, leading to cell death. The precise mechanism of light-induced damage is unknown; however, oxidative stress is thought to be involved, based on the
Autor:
Joe G. Hollyfield, Ruth M. Darrow, Masaru Miyagi, Daniel T. Organisciak, Hirokazu Sakaguchi, John W. Crabb, John S. Crabb
Publikováno v:
Experimental Eye Research. 76:131-133
Toward a better understanding of light-induced photoreceptor damage, the crystallin content of rat retina was examined following intense light exposure. Nine crystallin species were identified by mass spectrometric analysis of rat retina fractionated
Autor:
Daniel T. Organisciak, R. Darrow
Publikováno v:
Lipids. 29:591-594
A spectrophotometric method is described for the measurement of lipid hydroperoxides, to a lower limit of 0.5 nmoles, based on the formation of triiodide ions measured at the absorbance maximum of 365 nm. The assay mixture, which was modified from an