Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Daniel T. Montoro"'
Publikováno v:
eLife, Vol 12 (2023)
Despite advances in high-dimensional cellular analysis, the molecular profiling of dynamic behaviors of cells in their native environment remains a major challenge. We present a method that allows us to couple the physiological behaviors of cells in
Externí odkaz:
https://doaj.org/article/5ff329e624a248d297d673acb3be0790
Autor:
Hongmei Mou, Ying Yang, Molly A. Riehs, Juliana Barrios, Manjunatha Shivaraju, Adam L. Haber, Daniel T. Montoro, Kimberly Gilmore, Elisabeth A. Haas, Brankica Paunovic, Jayaraj Rajagopal, Sara O. Vargas, Robin L. Haynes, Alan Fine, Wellington V. Cardoso, Xingbin Ai
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109011- (2021)
Summary: Pulmonary neuroendocrine cells (PNECs) have crucial roles in airway physiology and immunity by producing bioactive amines and neuropeptides (NPs). A variety of human diseases exhibit PNEC hyperplasia. Given accumulated evidence that PNECs re
Externí odkaz:
https://doaj.org/article/7621fa35a8d64e0f93f6da88caccc9ac
Autor:
Karthik A. Jagadeesh, Kushal K. Dey, Daniel T. Montoro, Rahul Mohan, Steven Gazal, Jesse M. Engreitz, Ramnik J. Xavier, Alkes L. Price, Aviv Regev
Publikováno v:
Nature Genetics. 54:1479-1492
Publikováno v:
eLife. 12
Despite advances in high-dimensional cellular analysis, the molecular profiling of dynamic behaviors of cells in their native environment remains a major challenge. We present a method that allows us to couple the physiological behaviors of cells in
Autor:
Yuval Rinkevich, Daniel T. Montoro, Humberto Contreras-Trujillo, Orit Harari-Steinberg, Aaron M. Newman, Jonathan M. Tsai, Xinhong Lim, Renee Van-Amerongen, Angela Bowman, Michael Januszyk, Oren Pleniceanu, Roel Nusse, Michael T. Longaker, Irving L. Weissman, Benjamin Dekel
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 1270-1283 (2014)
The mechanism and magnitude by which the mammalian kidney generates and maintains its proximal tubules, distal tubules, and collecting ducts remain controversial. Here, we use long-term in vivo genetic lineage tracing and clonal analysis of individua
Externí odkaz:
https://doaj.org/article/5859db2fcb9a4aee8444a48bed517787
Autor:
Jay H. Lefkowitch, Samuel F. Bakhoum, George A. Alba, Denis Schapiro, Yaron Bram, Patricia Ho, Ajay Nair, Anjali Saqi, Yiping Wang, Robert E. Schwartz, Daniel T. Montoro, Armando Del Portillo, Jianwen Que, Alain C. Borczuk, Robert F. Schwabe, Sean W. Chen, André F. Rendeiro, Johannes C. Melms, Somnath Tagore, Hanina Hibshoosh, Adrienne M. Luoma, Adam E. Kornberg, Amit Dipak Amin, Mariano G. Clausi, Niroshana Anandasabapathy, Chris J. Frangieh, Stephen M. Lagana, Olivier Elemento, Yinshan Fang, Huachao Huang, Igor Katsyv, Mayte Suárez-Fariñas, Xinzheng V. Guo, Benjamin Izar, Emily J. Tsai, Charles C. Marboe, Mathieu F. Bakhoum, Aveline Filliol, Glen S. Markowitz, Hiranmayi Ravichandran, Arnold Han, Emmanuel Zorn, Meri Rogava, Jana Biermann
Publikováno v:
Nature. 595:114-119
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2 infection1,2, but the host response at the lung tissue level is poorly understood. Here we performed single-nucleus RNA sequencing of about 116,000 nuclei from the l
Autor:
Patrick R. Sears, Hanan E. Shamseldin, Heymut Omran, Katharine E. Black, Maimoona A. Zariwala, Vladimir Vinarsky, Evgeni M. Frenkel, David M. Sabatini, Hui Min Leung, Fowzan S. Alkuraya, Michael R. Knowles, Guillermo J. Tearney, Lida P. Hariri, M. Leigh Anne Daniels, Jason H. Yang, Martin S. Taylor, Raghu R. Chivukula, Johnny L. Carson, Ibrahim Almogarri, Daniel T. Montoro, Gerard W. Dougherty
Publikováno v:
Nature medicine
Mucociliary clearance, the physiological process by which mammalian conducting airways expel pathogens and unwanted surface materials from the respiratory tract, depends on the coordinated function of multiple specialized cell types, including basal
Despite advances in spatial transcriptomics, the molecular profiling of dynamic behaviors of cells in their native environment remains a major challenge. We present a method, termed behavioral transcriptomics, that allows us to couple physiological b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17fd46c6abae488e5d652c17fc9357e4
https://doi.org/10.1101/2022.01.31.478519
https://doi.org/10.1101/2022.01.31.478519
Autor:
Karthik A, Jagadeesh, Kushal K, Dey, Daniel T, Montoro, Rahul, Mohan, Steven, Gazal, Jesse M, Engreitz, Ramnik J, Xavier, Alkes L, Price, Aviv, Regev
Publikováno v:
Nature genetics. 54(10)
Genome-wide association studies provide a powerful means of identifying loci and genes contributing to disease, but in many cases, the related cell types/states through which genes confer disease risk remain unknown. Deciphering such relationships is