Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daniel T. MacLeod"'
Autor:
Florian Schmidt, Hannah F. Fields, Yovita Purwanti, Ana Milojkovic, Syazwani Salim, Kan Xing Wu, Yannick Simoni, Antonella Vitiello, Daniel T. MacLeod, Alessandra Nardin, Evan W. Newell, Katja Fink, Andreas Wilm, Michael Fehlings
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113250- (2023)
Summary: Following viral infection, the human immune system generates CD8+ T cell responses to virus antigens that differ in specificity, abundance, and phenotype. A characterization of virus-specific T cell responses allows one to assess infection h
Externí odkaz:
https://doaj.org/article/d6eded1c85f54ddc91bb785b41d88019
Autor:
Aaron Martin, Jeff Smith, Matthew L. Hirsch, Rachel J. Moser, Jo Ann Hux, Clayton W. Beard, Bruce J. Mccreedy, Melissa A. Triggiano, Daniel T. MacLeod, Victor V. Bartsevich, Michael G. Nicholson, Caitlin Turner, Audrey E. Brown, Christina D. Pham, Samantha Kirkland, Janel Lape, Armin Hekele, Jeyaraj Antony, Derek Jantz, Keith J. Wetzel
Publikováno v:
Molecular Therapy
Adoptive cellular therapy using chimeric antigen receptor (CAR) T cell therapies have produced significant objective responses in patients with CD19+ hematological malignancies, including durable complete responses. Although the majority of clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8027fcb2f728f1ba32719f1d31231ca7
Publikováno v:
The Journal of investigative dermatology
The Journal of investigative dermatology, vol 135, iss 1
The Journal of investigative dermatology, vol 135, iss 1
Patients with altered skin immunity, such as individuals with atopic dermatitis (AD), can have a life-threatening disruption of the epidermis known as eczema vaccinatum (EV) after vaccinia virus (VV) infection of the skin. Here, we sought to better u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b574d8a200d296a8556c7adad5a18ef
http://europepmc.org/articles/PMC4268046
http://europepmc.org/articles/PMC4268046
Autor:
Kemal Eren, Dennis R. Burton, J Gilmour, Etienne Karita, Fernando Garces, Terri Wrin, Lalinda Wickramasinghe, Ian A. Wilson, Nancy M. Choi, Daniel T. MacLeod, Leopold Kong, Eric Hunter, Shabir Lakhi, Chi-Huey Wong, Chaoran B. Bian, Vinodh A. Edward, Chung-Yi Wu, Susan Allen, Anatoli Kamali, William Kilembe, Pascal Poignard, Mubiana Inambao, Eduard J. Sanders, Bryan Briney, Elise Landais, Matthew Price, Sergei L. Kosakovsky Pond, Chi-Hui Liang, Alejandra Ramos, Linda-Gail Bekker, Ben Murrell, Lorena S. Ver, Omu Anzala, Pat Fast
Publikováno v:
Immunity
Immunity, 2016, 44 (5), pp.1215-26. ⟨10.1016/j.immuni.2016.04.016⟩
Immunity, Elsevier, 2016, 44 (5), pp.1215-26. ⟨10.1016/j.immuni.2016.04.016⟩
Immunity, 2016, 44 (5), pp.1215-26. ⟨10.1016/j.immuni.2016.04.016⟩
Immunity, Elsevier, 2016, 44 (5), pp.1215-26. ⟨10.1016/j.immuni.2016.04.016⟩
International audience; The high-mannose patch on HIV Env is a preferred target for broadly neutralizing antibodies (bnAbs), but to date, no vaccination regimen has elicited bnAbs against this region. Here, we present the development of a bnAb lineag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00326b2a4d5f7e69edf2422eebb94d6e
https://hal.univ-grenoble-alpes.fr/hal-01341105
https://hal.univ-grenoble-alpes.fr/hal-01341105
Publikováno v:
The Journal of Immunology. 189:1551-1558
Mast cells (MCs) are considered sentinels in the skin and mucosa. Their ability to release antimicrobial peptides, such as cathelicidin, protects against bacterial infections when the epithelial barrier is breached. We recently described that MCs def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5369178c38ac3c2d3e785a9052daf13
https://doi.org/10.4049/jimmunol.1200471
https://doi.org/10.4049/jimmunol.1200471
Autor:
Kenshi Yamasaki, Anna L. Cogen, Richard L. Gallo, Shin Morizane, Daniel T. MacLeod, Andrew W. Borkowski, Kimberly Natee Kanada, Teruaki Nakatsuji
Publikováno v:
Journal of Investigative Dermatology. 131(3):688-697
A diverse environment challenges skin to maintain temperature, hydration, and electrolyte balance while also maintaining normal immunological function. Rosacea is a common skin disease that manifests unique inflammatory responses to normal environmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8d01964705050590af1207a026c83d
Autor:
Hyun Jeong Park, Allen F. Ryan, Richard L. Gallo, Daniel T. MacLeod, Yuping Lai, Anna L. Cogen, Anna Di Nardo, Anke Leichtle, Katherine A. Radek
Publikováno v:
Journal of Investigative Dermatology. 130:2211-2221
Production of antimicrobial peptides by epithelia is an essential defense against infectious pathogens. In this study we evaluated whether the commensal microorganism Staphylococcus epidermidis may enhance production of antimicrobial peptides by kera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85eaebaee3b6a4b91ff264602e675bf2
https://doi.org/10.1038/jid.2010.123
https://doi.org/10.1038/jid.2010.123
Publikováno v:
Journal of Investigative Dermatology. 129:2148-2155
Innate immune responses involve the production of antimicrobial peptides (AMPs), chemokines, and cytokines. We report here the identification of B-cell leukemia (Bcl)-3 as a modulator of innate immune signaling in keratinocytes. In this study, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411d7279221123d2e33748e771122991
https://doi.org/10.1038/jid.2009.49
https://doi.org/10.1038/jid.2009.49
Autor:
Michael L. Nicholson, Audrey E. Brown, Ginger Tomberlin, Wendy Sharer, Bruce J. Mccreedy, Caitlin Turner, Jo Ann Hux, Victor Bartsevich, Daniel T. MacLeod, Derek Jantz, Janel Lape, Aaron Martin, Jeffrey S. Smith, Christina D. Pham, Jeyaraj Antony
Publikováno v:
Molecular Therapy. 24:S78
The manufacture of CAR-T cells depends on peripheral blood donations that contain T cells of sufficient quality and quantity. Currently, many CAR-T programs rely on autologous T cells, but several technical and commercial challenges hinder developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b6650e936842f5b2e50a3b3e82ae08e
https://doi.org/10.1016/s1525-0016(16)33009-x
https://doi.org/10.1016/s1525-0016(16)33009-x
Autor:
Audrey E Brown, Daniel T. MacLeod, Aaron J. Martin, Keith J. Wetzel, Christina D. Pham, Jeyaraj Antony, Bruce McCreedy, Victor V. Bartsevich, Michael G. Nicholson, Jeff Smith, Derek Jantz
Publikováno v:
The Journal of Immunology. 196:138.2-138.2
Recent reports describing allogeneic chimeric antigen receptor (CAR) T cell therapies have generated tremendous excitement over the possibility of a universal CAR T platform. We are utilizing a highly engineered meganuclease designed to target the T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24a2b7dd740ce0661dd606bed4e52934
https://doi.org/10.4049/jimmunol.196.supp.138.2
https://doi.org/10.4049/jimmunol.196.supp.138.2