Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Daniel T. Carr"'
Autor:
Michael G. Kiflezghi, Sunny Nguyen, Mary Ann K. Li, Socheata Thon, Brian M. Wasko, Yordanos C. Elala, Matt Kaeberlein, Daniel E. L. Promislow, Katherine A. Grayden, Thu H. B. Tran, Mitsuhiro Tsuchiya, Yan Ting Zhao, Irika Sinha, Mitchell B. Lee, Deborah Kim, Karl Rodriguez, Ngoc Han Tran, Daniel T. Carr, Jesse Wang, Tu Anh Nguyen, Thao T Tang, Margarete D. Moore, Priya Ragosti, Priya A. Uppal
Publikováno v:
GeroScience
As the molecular mechanisms of biological aging become better understood, there is growing interest in identifying interventions that target those mechanisms to promote extended health and longevity. The budding yeast Saccharomyces cerevisiae has ser
Autor:
Timothy Heck, Katherine D. Watson, Pamela S. Hair, Daniel T. Carr, Neel K. Krishna, William Owen, Jessica Price, Kenji M. Cunnion
Publikováno v:
Journal of Hematology
A 14-year-old female patient with sickle cell disease developed a severe delayed hemolytic transfusion reaction (DHTR) leading to multiple transfusions and intensive care management. To better understand the extent to which the classical complement p
Autor:
Scott R. Kennedy, Alan J. Herr, Thu H. B. Tran, Ian T. Dowsett, Mitchell B. Lee, Niloufar Ghodsian, Anh B. Diep, Michael G. Kiflezghi, Michael S. Chung, Daniel T. Carr, Katherine A. Grayden, Anna Bode, Thao T Tang, Priya A. Uppal, Daniel E. L. Promislow, Ngoc Han Tran, Brian M. Wasko, Sarah G. Stanton, Yordanos C. Elala, Michael Hope, Matt Kaeberlein
Publikováno v:
Proceedings of the National Academy of Sciences. 116:3062-3071
Mutations accumulate within somatic cells and have been proposed to contribute to aging. It is unclear what level of mutation burden may be required to consistently reduce cellular lifespan. Human cancers driven by a mutator phenotype represent an in
Autor:
Mitchell B. Lee, Michael G. Kiflezghi, Mitsuhiro Tsuchiya, Brian Wasko, Daniel T. Carr, Priya A. Uppal, Katherine A. Grayden, Yordanos C. Elala, Tu Anh Nguyen, Jesse Wang, Priya Rastogi, Sunny Nguyen, Yan Ting Zhao, Deborah Kim, Socheata Thon, Irika Sinha, Thao T. Tang, Ngoc H. B. Tran, Thu H. B. Tran, Margarete D. Moore, Mary Ann K. Li, Karl Rodriguez, Daniel E. L. Promislow, Matt Kaeberlein
Publikováno v:
GeroScience. 44:1889-1889
Autor:
Brian M Wasko, Daniel T Carr, Herman Tung, Ha Doan, Nathan Schurman, Jillian R Neault, Joey Feng, Janet Lee, Ben Zipkin, Jacob Mouser, Edward Oudanonh, Tina Nguyen, Torin Stetina, Anna Shemorry, Mekedes Lemma, Matt Kaeberlein
Publikováno v:
F1000Research, Vol 2 (2013)
During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival. As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standa
Externí odkaz:
https://doaj.org/article/d509173d851b48a18df952effce209ff
Autor:
Matt Kaeberlein, Daniel T. Carr, Michael G. Kiflezghi, Margarete D. Moore, Mitchell B. Lee, Mary Ann K. Li, Socheata Thon, Yan Ting Zhao, Deborah B. Kim
Publikováno v:
GeroScience. 39:419-428
The mechanistic target of rapamycin (mTOR) is a central regulator of growth and proliferation and mTOR inhibition is a promising therapy for a variety of diseases and disorders. Inhibition of mTOR complex I (mTORC1) with rapamycin delays aging and in
Autor:
Kajia Cao, Greg Donahue, Chong He, Weiwei Dang, Daniel T. Carr, Jun Yeop Lee, Rocco Perry, Shelley L. Berger, Junbiao Dai, Brian M. Wasko, Matt Kaeberlein, Brian D. Gregory, Jef D. Boeke, Wei Liu, John D. Wagner, Brett Robison, Brian K. Kennedy, Jean Dorsey, Xiaohua Cao, Payel Sen
Publikováno v:
Genesdevelopment. 29(13)
Epigenetic mechanisms, including histone post-translational modifications, control longevity in diverse organisms. Relatedly, loss of proper transcriptional regulation on a global scale is an emerging phenomenon of shortened life span, but the specif
Autor:
Mekedes Lemma, Herman Tung, Ben Zipkin, Brian M. Wasko, Nathan Schurman, Jacob Mouser, Tina Nguyen, Joey Feng, Ha Doan, Torin F. Stetina, Matt Kaeberlein, Jillian R Neault, Anna Shemorry, Daniel T. Carr, Edward Oudanonh, Janet S. Lee
Publikováno v:
F1000Research
During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival. As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standa
Autor:
Daniel T Carr
Publikováno v:
American Journal of Orthodontics and Oral Surgery. 31:152-160