Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniel T Youmans"'
Autor:
Jacob M Vogan, Xiaozhu Zhang, Daniel T Youmans, Samuel G Regalado, Joshua Z Johnson, Dirk Hockemeyer, Kathleen Collins
Publikováno v:
eLife, Vol 5 (2016)
We dissected the importance of human telomerase biogenesis and trafficking pathways for telomere maintenance. Biological stability of human telomerase RNA (hTR) relies on H/ACA proteins, but other eukaryotes use other RNP assembly pathways. To invest
Externí odkaz:
https://doaj.org/article/7193f9ced9e947cf8f83b9491ed498d1
Publikováno v:
Mol Cell
Polycomb repressive complex 2 (PRC2) silences expression of developmental transcription factors in pluripotent stem cells by methylating lysine 27 on histone H3. Two mutually exclusive subcomplexes, PRC2.1 and PRC2.2, are defined by the set of access
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b96778e8ac97653b2c42a2441e829b
https://doi.org/10.1016/j.molcel.2020.11.044
https://doi.org/10.1016/j.molcel.2020.11.044
Publikováno v:
Genesdevelopment. 32(11-12)
Polycomb-repressive complex 2 (PRC2) is a histone methyltransferase that promotes epigenetic gene silencing, but the dynamics of its interactions with chromatin are largely unknown. Here we quantitatively measured the binding of PRC2 to chromatin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0dbf5411417bfaf9db4494c1d708d8
https://pubmed.ncbi.nlm.nih.gov/29891558
https://pubmed.ncbi.nlm.nih.gov/29891558
Publikováno v:
Science Advances
Eukaryotic genomes encode thousands of long noncoding RNAs, and many of these function in transcriptional regulation.
It has recently become apparent that RNA, itself the product of transcription, is a major regulator of the transcriptional proc
It has recently become apparent that RNA, itself the product of transcription, is a major regulator of the transcriptional proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b23a9c40b5183647c08629c5a77845
https://doi.org/10.1126/sciadv.aao2110
https://doi.org/10.1126/sciadv.aao2110
Autor:
Daniel T. Youmans, Karen J. Goodrich, Stuart K. Archer, Chen Davidovich, Anne R. Gooding, Haroon Naeem, Richard D. Paucek, Xueyin Wang, Thomas R. Cech
Publikováno v:
Molecular cell. 65(6)
Polycomb repressive complex 2 (PRC2) is a histone methyltransferase that trimethylates H3K27, a mark of repressed chromatin. Mammalian PRC2 binds RNA promiscuously, with thousands of target transcripts in vivo. But what does PRC2 recognize in these R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46455d1da32fe5862f07f1b5534da66d
https://pubmed.ncbi.nlm.nih.gov/28306504
https://pubmed.ncbi.nlm.nih.gov/28306504
Autor:
Kathleen Collins, Joshua Z Johnson, Samuel G. Regalado, Jacob M. Vogan, Dirk Hockemeyer, Daniel T. Youmans, Xiaozhu Zhang
Publikováno v:
eLife, Vol 5 (2016)
Vogan, JM; Zhang, X; Youmans, DT; Regalado, SG; Johnson, JZ; Hockemeyer, D; et al.(2016). Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies. eLife, 5(AUGUST). doi: 10.7554/eLife.18221. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/67v7829g
eLife, vol 5, iss AUGUST
eLife
Vogan, JM; Zhang, X; Youmans, DT; Regalado, SG; Johnson, JZ; Hockemeyer, D; et al.(2016). Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies. eLife, 5(AUGUST). doi: 10.7554/eLife.18221. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/67v7829g
eLife, vol 5, iss AUGUST
eLife
We dissected the importance of human telomerase biogenesis and trafficking pathways for telomere maintenance. Biological stability of human telomerase RNA (hTR) relies on H/ACA proteins, but other eukaryotes use other RNP assembly pathways. To invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d13f4e7363c49ef885858c62261bb5
https://elifesciences.org/articles/18221
https://elifesciences.org/articles/18221
Publikováno v:
Journal of Biological Chemistry. 287:34455-34464
Human telomeres are maintained by the enzyme telomerase, which uses a template within its integral RNA subunit (hTR) and telomerase reverse transcriptase protein (TERT) to accomplish the synthesis of single-stranded DNA repeats. Many questions remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e38ba78963585065bc3442b333cff9
https://doi.org/10.1074/jbc.m112.394767
https://doi.org/10.1074/jbc.m112.394767
Publikováno v:
eLife; 7/4/2023, p1-31, 31p
Autor:
Vogan, Jacob M., Xiaozhu Zhang, Youmans, Daniel T., Regalado, Samuel G., Johnson, Joshua Z., Hockemeyer, Dirk, Collins, Kathleen
Publikováno v:
eLife; 2016, p1-21, 21p