Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Daniel T Ohm"'
Autor:
Lucia AA Giannini, Merel O Mol, Ana Rajicic, Renee van Buuren, Lana Sarkar, Sanaz Arezoumandan, Daniel T Ohm, David J Irwin, Annemieke JM Rozemuller, Netherlands Brain Bank, John C van Swieten, Harro Seelaar
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Early pathological features of frontotemporal lobar degeneration (FTLD) due to MAPT pathogenic variants (FTLD-MAPT) are understudied, since early-stage tissue is rarely available. Here, we report unique pathological data from three presympto
Externí odkaz:
https://doaj.org/article/233371915a9f40739440fe3dd0d35b5a
Autor:
Adam Martersteck, Ivan Ayala, Daniel T. Ohm, Callen Spencer, Christina Coventry, Sandra Weintraub, Eileen H. Bigio, M. -Marsel Mesulam, Changiz Geula, Emily Rogalski
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Quantification of in vivo amyloid and tau PET imaging relationships with postmortem measurements are critical for validating the sensitivity and specificity imaging biomarkers across clinical phenotypes with Alzheimer disease neuropathologic
Externí odkaz:
https://doaj.org/article/dee5d657b80b4aea9235b2ab51caffdc
Autor:
M. Dylan Tisdall, Daniel T. Ohm, Rebecca Lobrovich, Sandhitsu R. Das, Gabor Mizsei, Karthik Prabhakaran, Ranjit Ittyerah, Sydney Lim, Corey T. McMillan, David A. Wolk, James Gee, John Q. Trojanowski, Edward B. Lee, John A. Detre, Paul Yushkevich, Murray Grossman, David J. Irwin
Publikováno v:
NeuroImage: Clinical, Vol 33, Iss , Pp 102913- (2022)
Frontotemporal lobar degeneration (FTLD) is a heterogeneous spectrum of age-associated neurodegenerative diseases that include two main pathologic categories of tau (FTLD-Tau) and TDP-43 (FTLD-TDP) proteinopathies. These distinct proteinopathies are
Externí odkaz:
https://doaj.org/article/bdcc86440dd24ea7bdac41da36329d85
Autor:
Hyung Seok Roh, David J. Irwin, Mónica Muñoz López, Maria Mercedes Iñiguez de Onzoño Martin, Ranjit Ittyerah, Sydney Lim, Madigan L. Bedard, John L. Robinson, Theresa Schuck, Emilio Artacho-Pérula, María del Mar Arroyo Jiménez, María Pilar Marcos Rabal, Francisco Javier Molina Romero, Sandra Cebada Sánchez, José Carlos Delgado González, Carlos de la Rosa-Prieto, Marta Córcoles Parada, Edward B. Lee, Daniel T. Ohm, Laura E. M. Wisse, David A. Wolk, James C. Gee, Ricardo Insausti, Paul A. Yushkevich, Min Chen
Publikováno v:
Medical Imaging 2023: Digital and Computational Pathology.
Autor:
Min Chen, Daniel T. Ohm, Jeffrey S. Phillips, Corey T. McMillan, Noah Capp, Claire Peterson, Emily Xie, David A. Wolk, John Q. Trojanowski, Edward B. Lee, James Gee, Murray Grossman, David J. Irwin
Publikováno v:
The Journal of Neuroscience. 42:3868-3877
Network analyses inform complex systems such as human brain connectivity, but this approach is seldom applied to gold-standard histopathology. Here, we use two complimentary computational approaches to model microscopic progression of the main subtyp
Autor:
Pulkit Khandelwal, Shokufeh Sadaghiani, Eunice Chung, Sydney A Lim, Michael Tran Duong, Sadhana Ravikumar, Sanaz Arezoumandan, Claire Peterson, Madigan L Bedard, Noah Capp, Ranjit Ittyerah, Elyse Migdal, Grace Choi, Emily Kopp, Bridget Loja Patino, Eusha Hasan, Jiacheng Li, Karthik Prabhakaran, Gabor Mizsei, Marianna Gabrielyan, Theresa Schuck, John Robinson, Daniel T Ohm, Eddie B Lee, John Q Trojanowski, Corey T McMillan, Murray Grossman, David J. Irwin, Dylan M Tisdall, Sandhitsu R. Das, Laura EM Wisse, David A. Wolk, Paul A. Yushkevich
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Pulkit Khandelwal, Michael Tran Duong, Eunice Chung, Shokufeh Sadaghiani, Sydney A Lim, Sadhana Ravikumar, Sanaz Arezoumandan, Claire Peterson, Madigan L Bedard, Noah Capp, Ranjit Ittyerah, Elyse Migdal, Grace Choi, Emily Kopp, Bridget Loja Patino, Eusha Hasan, Jiacheng Li, Karthik Prabhakaran, Gabor Mizsei, Marianna Gabrielyan, Theresa Schuck, John L. Robinson, Daniel T Ohm, Ilya M. Nasrallah, Eddie B Lee, John Q Trojanowski, Corey T McMillan, Murray Grossman, David J. Irwin, Dylan M Tisdall, Sandhitsu R. Das, Laura EM Wisse, David A. Wolk, Paul A. Yushkevich
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Shokufeh Sadaghiani, Winifred Trotman, Sydney A. Lim, Eunice Chung, Ranjit Ittyerah, Sadhana Ravikumar, Pulkit Khandelwal, Karthik Prabhakaran, Madigan L. Lavery, Daniel T. Ohm, Marianna Gabrielyan, Sandhitsu R. Das, Theresa Schuck, Noah Capp, Claire S. Peterson, Elyse Migdal, Emilio Artacho‐Pérula, María del Mar Arroyo Jiménez, Maria del Pilar Marcos Rabal, Sandra Cebada Sánchez, Carlos de la Rosa Prieto, Marta Córcoles Parada, Ricardo Insausti, John L. Robinson, Corey McMillan, Murray Grossman, Edward B. Lee, John A. Detre, Sharon X. Xie, John Q. Trojanowski, M. Dylan Tisdall, Laura E. M. Wisse, David J. Irwin, David A. Wolk, Paul A. Yushkevich
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
Neurodegenerative disorders are associated with different pathologies that often co-occur but cannot be measured specifically with in vivo methods.Thirty-three brain hemispheres from donors with an Alzheimer's disease (AD) spectrum diagnosis underwen
Autor:
Sanaz Arezoumandan, Sharon X. Xie, Katheryn A. Q. Cousins, Dawn J. Mechanic-Hamilton, Claire S. Peterson, Camille Y. Huang, Daniel T. Ohm, Ranjit Ittyerah, Corey T. McMillan, David A. Wolk, Paul Yushkevich, John Q. Trojanowski, Edward B. Lee, Murray Grossman, Jeffrey S. Phillips, David J. Irwin
Publikováno v:
Acta Neuropathol
Alzheimer’s disease neuropathologic change (ADNC) is clinically heterogenous and can present with a classic multidomain amnestic syndrome or focal non-amnestic syndromes. Here, we investigated the distribution and burden of phosphorylated and C-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c58a2331e11f7de110cd87437c2618
https://europepmc.org/articles/PMC9936795/
https://europepmc.org/articles/PMC9936795/
Autor:
Lucia A A, Giannini, Daniel T, Ohm, Annemieke J M, Rozemuller, Laynie, Dratch, EunRan, Suh, Vivianna M, van Deerlin, John Q, Trojanowski, Edward B, Lee, John C, van Swieten, Murray, Grossman, Harro, Seelaar, David J, Irwin
Publikováno v:
Acta neuropathologica. 144(6)
Frontotemporal lobar degeneration with MAPT pathogenic variants (FTLD-MAPT) has heterogeneous tau pathological inclusions postmortem, consisting of three-repeat (3R) or four-repeat (4R) tau isoforms, or a combination (3R + 4R). Here, we studied grey