Zobrazeno 1 - 2
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pro vyhledávání: '"Daniel T L Chow"'
Autor:
Jeremy P H Chow, Yijun Cai, Daniel T L Chow, Steven H K Chung, Ka-Chun Chau, Ka-Ying Ng, Oscar M Leung, Raymond M H Wong, Alan W L Law, Yu-On Leung, Sui-Yi Kwok, Yun-Chung Leung
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231633 (2020)
Arginine deprivation cancer therapy targets certain types of malignancies with positive result in many studies and clinical trials. NEI-01 was designed as a novel arginine-depleting enzyme comprising an albumin binding domain capable of binding to hu
Externí odkaz:
https://doaj.org/article/bd15953893f24e5099c3a2da3249ef8d
Autor:
Yijun, Cai, Jeremy P H, Chow, Yu-On, Leung, Xiaoxu, Lu, Chak-Ho, Yuen, Wing Lun, Lee, Ka-Chun, Chau, Liz L, Yang, Raymond M H, Wong, Justin Y T, Lam, Daniel T L, Chow, Steven H K, Chung, Sui-Yi, Kwok, Yun-Chung, Leung
Publikováno v:
Molecular cancer therapeutics. 20(11)
Recent studies have revealed that targeting amino acid metabolic enzymes is a promising strategy in cancer therapy. Acute myeloid leukemia (AML) downregulates the expression of argininosuccinate synthase (ASS1), a recognized rate-limiting enzyme for