Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel Solvie"'
Autor:
Sofia Henriksson, José Manuel Calderón-Montaño, Daniel Solvie, Ulrika Warpman Berglund, Thomas Helleday
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1777 (2022)
Previously, we reported that MTH1 inhibitors TH588 and TH1579 selectively induce oxidative damage and kill Ras-expressing or -transforming cancer cells, as compared to non-transforming immortalized or primary cells. While this explains the impressive
Externí odkaz:
https://doaj.org/article/a6ba012771674b829f8b030ca70888d3
Autor:
Daniel Solvie, Apoorva Baluapuri, Leonie Uhl, Daniel Fleischhauer, Theresa Endres, Dimitrios Papadopoulos, Amel Aziba, Abdallah Gaballa, Ivan Mikicic, Ekaterina Isaakova, Celeste Giansanti, Jennifer Jansen, Marvin Jungblut, Teresa Klein, Christina Schülein-Völk, Hans Maric, Sören Doose, Markus Sauer, Petra Beli, Andreas Rosenwald, Matthias Dobbelstein, Elmar Wolf, Martin Eilers
Publikováno v:
Nature. 612:148-155
Oncoproteins of the MYC family drive the development of numerous human tumours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7ed7ca17b0ff6d2e1e4c473ef0801a
https://doi.org/10.1038/s41586-022-05469-4
https://doi.org/10.1038/s41586-022-05469-4
Autor:
Michaela Reissland, Oliver Hartmann, Saskia Tauch, Cristian Prieto-Garcia, Clemens Schulte, Daniel Solvie, Sinah Loebbert, Anne-Claire Jacomin, Marina Pesic, Jeroen Bugter, Christina Schülein-Völk, Carmina Fuss, Nikolett Pahor, Carsten Ade, Viktoria Buck, Michael Potente, Vivian Li, Gerti Beliu, Armin Wiegering, Eliya Bitman-Lotan, Tom Grossmann, Mathias Rosenfeldt, Martin Eilers, Hans Maric, Madelon Maurice, Florian Greten, Ivan Dikic, Amir Oryan, Peter Gallant, Markus Diefenbacher
The contribution of deubiquitylating enzymes to β-Catenin stabilisation in intestinal stem cells and colorectal cancer (CRC) is poorly understood. Here, we report the deubiquitylase USP10 as an APC-truncation- specific enhancer of β-Catenin stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cbc08d25e5786a9e89293d3727f74c9
https://doi.org/10.21203/rs.3.rs-2647009/v1
https://doi.org/10.21203/rs.3.rs-2647009/v1
Autor:
Michaela Reissland, Oliver Hartmann, Saskia Tauch, Cristian Prieto-Garcia, Clemens Schulte, Daniel Solvie, Sinah Loebbert, Anne-Claire Jacomin, Marina Pesic, Jeroen M. Bugter, Christina Schuelein-Voelk, Carmina T. Fuss, Nikolet Pahor, Carsten Ade, Viktoria Buck, Michael Potente, Vivian Li, Gerti Beliu, Armin Wiegering, Eliya Bitman-Lotan, Tom Grossmann, Mathias Rosenfeldt, Martin Eilers, Hans Maric, Madelon M. Maurice, Florian Greten, Ivan Dikič, Amir Orian, Peter Gallant, Markus E. Diefenbacher
SummaryThe contribution of deubiquitylating enzymes to β-Catenin stabilisation in intestinal stem cells and colorectal cancer (CRC) is poorly understood. Here, we report the deubiquitylase USP10 as an APC-truncation- specific enhancer of β-Catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07cbccc13dc3cb445f4a5957beac5545
https://doi.org/10.1101/2023.02.10.527983
https://doi.org/10.1101/2023.02.10.527983
Autor:
Elmar Wolf, Martin Eilers, Jan Koster, Apoorva Baluapuri, Rogier Versteeg, Sabrina Rodewald, Daniel Solvie, Gabriele Büchel, Jacqueline Kalb, Carsten P. Ade, Jiajia Xu, Steffi Herold, Jan J. Molenaar, Anne Carstensen, Susanne Walz, Matthias Dobbelstein, Christina Klotz, Christina Schülein-Völk
Publikováno v:
Nature, 567(7749), 545-549. Nature Publishing Group
Nature
Nature
MYC is an oncogenic transcription factor that binds globally to active promoters and promotes transcriptional elongation by RNA polymerase II (RNAPII) 1,2 . Deregulated expression of the paralogous protein MYCN drives the development of neuronal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37bd98d02d532b4bdc8b99c953d2313
https://pure.amc.nl/en/publications/recruitment-of-brca1-limits-mycndriven-accumulation-of-stalled-rna-polymerase(d9d6a680-7598-45d0-9639-443cc9d59a22).html
https://pure.amc.nl/en/publications/recruitment-of-brca1-limits-mycndriven-accumulation-of-stalled-rna-polymerase(d9d6a680-7598-45d0-9639-443cc9d59a22).html
Autor:
Seychelle M. Vos, Jan B. Heidelberger, Peter Gallant, Petra Beli, Nikita Popov, Elmar Wolf, Carsten P. Ade, Johannes Zuber, Matthias Muhar, Valentina Andrioletti, Ursula Eilers, Theresa Endres, Daniel Solvie, Apoorva Baluapuri, Martin Eilers, Patrick Cramer
Publikováno v:
Mol Cell
Molecular Cell
Molecular Cell
The MYC oncoprotein globally affects the function of RNA polymerase II (RNAPII). The ability of MYC to promote transcription elongation depends on its ubiquitylation. Here, we show that MYC and PAF1c (polymerase II-associated factor 1 complex) intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9839c96563f931a2669fbb41b757e6