Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Daniel Soetkamp"'
S‐Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S‐Nitrosylation and Preeclampsia
Autor:
Shathiyah Kulandavelu, Raul A. Dulce, Christopher I. Murray, Michael A. Bellio, Julia Fritsch, Rosemeire Kanashiro‐Takeuchi, Himanshu Arora, Ellena Paulino, Daniel Soetkamp, Wayne Balkan, Jenny E. Van Eyk, Joshua M. Hare
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)
Background Preeclampsia, a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S‐nitrosylated proteins and reactive oxygen species, suggesting a pathophysiologic role for dysregulation in nitrosylation an
Externí odkaz:
https://doaj.org/article/7c58d4a5e22d48efa2ccc96e5a6e59bc
Autor:
Ryan C. Middleton, Russell G. Rogers, Geoffrey De Couto, Eleni Tseliou, Kristin Luther, Ronald Holewinski, Daniel Soetkamp, Jennifer E. Van Eyk, Travis J. Antes, Eduardo Marbán
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Newts can regenerate amputated limbs and cardiac tissue, unlike mammals which lack broad regenerative capacity. Several signaling pathways involved in cell proliferation, differentiation and survival during newt tissue regeneration have been elucidat
Externí odkaz:
https://doaj.org/article/f6a012b05ee847b498316ab3b6138261
Autor:
James F. Dawkins, Ashkan Ehdaie, Russell Rogers, Daniel Soetkamp, Jackelyn Valle, Kevin Holm, Lizbeth Sanchez, Ileana Tremmel, Asma Nawaz, Michael Shehata, Xunzhang Wang, Adityo Prakosa, Joseph Yu, Jennifer E Van Eyk, Natalia Trayanova, Eduardo Marbán, Eugenio Cingolani
Publikováno v:
European heart journal, vol 43, iss 22
Eur Heart J
Eur Heart J
Aims Cardiomyopathy patients are prone to ventricular arrhythmias (VA) and sudden cardiac death. Current therapies to prevent VA include radiofrequency ablation to destroy slowly conducting pathways of viable myocardium which support re-entry. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db28646d9dad2e825c1283d50a4abde
https://escholarship.org/uc/item/63m7g23h
https://escholarship.org/uc/item/63m7g23h
Autor:
Daniel Soetkamp, Joshua I. Goldhaber, Jennifer E. Van Eyk, Sarah J. Parker, Eduardo Marbán, Ronald J. Holewinski, Kiel Peck, Romain Gallet, Vidya Venkatraman
Publikováno v:
Circ Res
Circulation research, vol 129, iss 12
Circulation research, vol 129, iss 12
Rationale: Phosphorylation of sarcomeric proteins has been implicated in heart failure with preserved ejection fraction (HFpEF); such changes may contribute to diastolic dysfunction by altering contractility, cardiac stiffness, Ca 2+ -sensitivity, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d39ab45eac756fc821cb8e6c6cc694
https://pubmed.ncbi.nlm.nih.gov/34641704
https://pubmed.ncbi.nlm.nih.gov/34641704
Autor:
Daniel Soetkamp, Peter J. Kilfoil, Aleksandra Binek, G. de Couto, J. E. Van Eyk, Amy D. Bradshaw, Joshua I. Goldhaber, Eduardo Marbán, Ronald J. Holewinski, Vidya Venkatraman, Rowann Mostafa, Michael R. Zile, Romain Gallet
IntroductionHeart failure with preserved ejection fraction (HFpEF) is characterized by diastolic dysfunction, pulmonary congestion and exercise intolerance. Previous preclinical studies show that treatment with cardiosphere-derived cells (CDCs) impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82da525e7ce7b5ac861398f7a9085c90
https://doi.org/10.1101/2021.09.06.456608
https://doi.org/10.1101/2021.09.06.456608
Autor:
Walter Schiffer, David J. R. Taylor, Daniel Soetkamp, Benjamin D. Gould, Jennifer E. Van Eyk, Anna Guzman, Weston R. Spivia, Lin Tan, Heinrich Taegtmeyer, Helen B. Burks, Blake Hanson, Anja Karlstaedt, Heidi Vitrac, Philip L. Lorenzi, Rebecca Salazar, Daniel McNavish, An Q Dinh, Roberta A. Gottlieb, Koen Raedschelders, Stavros Azinas
About 20-30% of cancer-associated deaths are due to complications from cachexia which is characterized by skeletal muscle atrophy. Metabolic reprogramming in cancer cells causes body-wide metabolic and proteomic remodeling, which remain poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de41df7869a7873d19bfadcb5e41a9c
https://doi.org/10.1101/2020.10.13.338202
https://doi.org/10.1101/2020.10.13.338202
S-nitrosoglutathione reductase deficiency causes aberrant placental S-nitrosylation and preeclampsia
Autor:
Christopher I. Murray, Ellena C. Paulino, Joshua M. Hare, Raul A Dulce, Shathiyah Kulandavelu, Rosemeire M. Kanashiro-Takeuchi, Julia Fritsch, Michael A. Bellio, Jennifer E. Van Eyk, Wayne Balkan, Himanshu Arora, Daniel Soetkamp
Preeclampsia (PE), a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S-nitrosylated (SNO) proteins and reactive oxygen species (ROS), suggesting a pathophysiologic role for dysregulation in nitrosylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c512152ea338b264ead55ba4000d19
https://doi.org/10.1101/2020.07.01.183012
https://doi.org/10.1101/2020.07.01.183012
Autor:
Kimia Sobhani, Mitra Mastali, Jennifer E. Van Eyk, Koen Raedschelders, Daniel Soetkamp, C. Noel Bairey Merz
Publikováno v:
Expert Review of Proteomics. 14:973-986
The troponin complex consists of three proteins that fundamentally couple excitation with contraction. Circulating cardiac-specific Troponin I (cTnI) serves as diagnostic biomarker tools for risk stratification of acute coronary syndromes and acute m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6eb235e874ca5510c4c9803f5ff71f
https://doi.org/10.1080/14789450.2017.1387054
https://doi.org/10.1080/14789450.2017.1387054
Autor:
Roberta A. Gottlieb, Helen B. Burks, Anja Karlstaedt, Rebecca Salazar, Jennifer VanEyk, David J. Taylor, An Dinh, Benjamin D. Gould, Daniel Soetkamp, Walter Schiffer, Blake Hanson, Heinrich Taegtmeyer, Weston R. Spivia, Daniel McNavish, Koen Raedschelders, Heidi Vitrac
Publikováno v:
Circulation Research. 125
Metabolic rewiring is a hallmark of cancer and muscle cells. In isocitrate dehydrogenase 1 and 2 mutant tumors, increased plasma levels of the oncometabolite D-2-hydroxyglutarate (D2-HG) are associated with systemic effects, including myopathy. Our r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48e590eb88f724176a5a658c1fe101f6
https://doi.org/10.1161/res.125.suppl_1.361
https://doi.org/10.1161/res.125.suppl_1.361
Autor:
Jennifer E. Van Eyk, Daniel Soetkamp, Padmesh S. Rajput, Jessica Lamb, Eric S. Mullins, Yizhou Wang, Patrick D. Lyden, Benedict Pereira, Jie Tang, Shweta Kothari
Publikováno v:
Glia
Astrocytes protect neurons during cerebral injury through several postulated mechanisms. Recent therapeutic attention has focused on enhancing or augmenting the neuroprotective actions of astrocytes but in some instances astrocytes can assume a neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb99413e4238033dbc19e52b9ad755e
https://pubmed.ncbi.nlm.nih.gov/31453648
https://pubmed.ncbi.nlm.nih.gov/31453648