Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Daniel Skomski"'
Publikováno v:
Journal of Pharmaceutical Sciences. 112:771-778
Imaging is commonly used as a characterization method in the pharmaceuticals industry, including for quantifying subvisible particles in solid and liquid formulations. Extracting information beyond particle size, such as classifying morphological sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebb000e863e56aa05658332a562778b
https://doi.org/10.1016/j.xphs.2022.10.010
https://doi.org/10.1016/j.xphs.2022.10.010
Publikováno v:
Pharmaceutical research.
Quantification of subvisible particles, which are generally defined as those ranging in size from 2 to 100 µm, is important as critical characteristics for biopharmaceutical formulation development. Micro Flow Imaging (MFI) provides quantifiable mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa19713c5ac45dffa610044e7d21927
https://pubmed.ncbi.nlm.nih.gov/36471026
https://pubmed.ncbi.nlm.nih.gov/36471026
Autor:
Hossein Salami, Daniel Skomski
Publikováno v:
Chemical Engineering Science. 278:118904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e72f03470e1eff2caae7d6710d971837
https://doi.org/10.1016/j.ces.2023.118904
https://doi.org/10.1016/j.ces.2023.118904
Autor:
Sutthilug Sotthivirat, R.V. Taggart, N. Afanador, Chad D. Brown, K. Rosenberg, Walter Wasylaschuk, J. Ren, Daniel Skomski
Publikováno v:
Journal of Pharmaceutical Sciences. 110:2934-2945
The goal of this study was to understand the impact of high-shear wet granulation (HSWG) processing conditions on product attributes for a tablet formulation containing the non-ionic surfactant TPGS. The use of TPGS in oral solid drug products has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5079e40ecda6641030731c9c2a6a530e
https://doi.org/10.1016/j.xphs.2021.03.015
https://doi.org/10.1016/j.xphs.2021.03.015
Autor:
Rishi Ramesh, Sutthilug Sotthivirat, Chad D. Brown, Binfeng Xia, Cory Bottone, Walter Wasylaschuk, Joyce Stellabott, Daniel Skomski, Michael J. McNevin
Publikováno v:
Powder Technology. 375:302-309
d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) has been widely used in a variety of oral applications to enhance dissolution, solubility, and/or bioavailability of poorly-water soluble drugs. In addition, the use of TPGS could potentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba693529060909ae37c3e57e71e2745
https://doi.org/10.1016/j.powtec.2020.07.093
https://doi.org/10.1016/j.powtec.2020.07.093
Autor:
Hanmi Xi, Xiangyu Ma, Mike Marsh, Robert E.A. Williams, Nicolas Piché, Nada Kittikunakorn, Bradley Sorman, Arthur Mongeau, Daniel Skomski, Antong Chen
Publikováno v:
Microscopy and Microanalysis. 26:1606-1609
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca245fcb5dbffcdf7b9695653b6aed61
https://doi.org/10.1017/s1431927620018693
https://doi.org/10.1017/s1431927620018693
Autor:
Yongchao Su, Ryan S. Teller, Wei Xu, Varsolona Richard J, Daniel Skomski, Seth P. Forster, Stephanie E. Barrett, Jingtao Zhang
Publikováno v:
Molecular Pharmaceutics. 17:2874-2881
The emergence of new active pharmaceutical ingredient (API) polymorphs in pharmaceutical development presents significant risks. Even with thorough polymorph screening, new pathways toward alternate crystal phases can present themselves over the cour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e711613fa8510e21a95b5ac8f4be5cf
https://doi.org/10.1021/acs.molpharmaceut.0c00316
https://doi.org/10.1021/acs.molpharmaceut.0c00316
Autor:
Chengbin Huang, Wei Xu, Xingyu Lu, Allen C. Templeton, Mingyue Li, Daniel Skomski, Lian Yu, Yongchao Su, Stephen R. Byrn
Publikováno v:
The Journal of Physical Chemistry B. 124:5271-5283
Crystalline and amorphous materials usually possess distinct physicochemical properties due to major variations in long-range and local molecular packings. Enhanced fundamental knowledge of the mol...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793076c50cd063f2afc593043f052a7c
https://doi.org/10.1021/acs.jpcb.0c02131
https://doi.org/10.1021/acs.jpcb.0c02131
Autor:
Robert F. Meyer, Daniel Skomski, Heidi Ferguson, Manoharan Ramasamy, Pierre Daublain, Allen C. Templeton, Yash Kapoor, Chad Dalton, Gregory M. Troup
Publikováno v:
Molecular pharmaceutics. 18(7)
The process of bringing a drug to market involves innumerable decisions to refine a concept into a final product. The final product goes through extensive research and development to meet the target product profile and to obtain a product that is man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfb66faab3b75f9510b9dc84e060075
https://pubmed.ncbi.nlm.nih.gov/34165309
https://pubmed.ncbi.nlm.nih.gov/34165309
Publikováno v:
Analytical Chemistry. 91:6217-6224
High-resolution solid-state analysis of multicomponent molecular systems, e.g., pharmaceutical formulations, is a great challenge. Solid-state nuclear magnetic resonance (ssNMR) spectroscopy plays a critical role in the characterization of solid dosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940e9bfc68a38872858c6abb671db605
https://doi.org/10.1021/acs.analchem.9b00884
https://doi.org/10.1021/acs.analchem.9b00884