Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniel Siuda"'
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216218 (2019)
The angiotensin-converting enzyme (ACE) plays a central role in the renin-angiotensin system, which is involved in the regulation of blood pressure. Alterations in ACE expression or activity are associated with various pathological phenotypes, partic
Externí odkaz:
https://doaj.org/article/29bf0c09a03b4794b61d2f056e750118
Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis
Autor:
Beate Fisslthaler, Nina Zippel, Randa Abdel Malik, Fredy Delgado Lagos, Sven Zukunft, Janina Thoele, Daniel Siuda, Oliver Soehnlein, Ilka Wittig, Juliana Heidler, Andreas Weigert, Ingrid Fleming
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3005 (2019)
The AMP-activated protein kinase (AMPK) is an energy sensing kinase that is activated by a drop in cellular ATP levels. Although several studies have addressed the role of the AMPKα1 subunit in monocytes and macrophages, little is known about the α
Externí odkaz:
https://doaj.org/article/4663e5abc50b481b9a102b9411365e32
Autor:
Christoph Schürmann, Juliana Heidler, Sofia Iris Bibli, Fragiska Sigala, Voahanginirina Randriamboavonjy, Bert Luck, Sven Zukunft, Ralf P. Brandes, Csaba Szabó, Andreas Papapetropoulos, Diamantis I. Tsilimigras, Mauro Siragusa, Daniel Siuda, Janina Wittig, Konstantinos Filis, Josef Pfeilschifter, Dao Wen Wang, Jiong Hu, George C. Zografos, Chen Chen, Randa Abdel Malik, Baktybek Kojonazarov, Ingrid Fleming, Ilka Wittig
Publikováno v:
Circulation. 139:101-114
Background: Hydrogen sulfide (H 2 S), generated by cystathionine γ lyase (CSE), is an important endogenous regulator of vascular function. The aim of the present study was to investigate the control and consequences of CSE activity in endothelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1b4586c7c1292be70fe2d49ebe679e
https://doi.org/10.1161/circulationaha.118.034757
https://doi.org/10.1161/circulationaha.118.034757
Publikováno v:
Biochimica et biophysica acta. Gene regulatory mechanisms. 1862(10)
Calpain 2 (CAPN2) is a Ca2+-dependent cysteine-protease that is involved in different cellular processes. Despite its important role, little is known about how CAPN2 expression is regulated. This study addressed the potential regulation of CAPN2 by m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46fcf09b3b13e120f966dac5f9c3b3e
https://pubmed.ncbi.nlm.nih.gov/31634637
https://pubmed.ncbi.nlm.nih.gov/31634637
Autor:
Andreas Daiber, Ning Xia, Huige Li, Thomas Münzel, Ulrich Förstermann, Gisela Reifenberg, Daniel Siuda, Zhixiong Wu
Publikováno v:
Hypertension. 65:232-237
Pentaerythritol tetranitrate is devoid of nitrate tolerance and shows no reproductive or developmental toxicity in animal studies. Recently, pentaerythritol tetranitrate has been demonstrated to reduce the risk of intrauterine growth restriction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f4905218c963fdb5eee0ff06bd6edf
https://doi.org/10.1161/hypertensionaha.114.04416
https://doi.org/10.1161/hypertensionaha.114.04416
Autor:
Julia Art, Matthias Bros, Katharina Schrick, Felix Behnke, Daniel Siuda, Oliver Werz, Huige Li, Norbert Handler, Franziska Bollmann, Lorena Härdle, Thomas Erker, Hartmut Kleinert, Bettina Mönch, Andrea Pautz, Florian Bauer, Verena Besche, Markus Hoffmann, Ulrich Förstermann, Verena M. Dirsch, Jenny Henke, Ching Yi Chen
Publikováno v:
Nucleic Acids Research
Resveratrol shows beneficial effects in inflammation-based diseases like cancer, cardiovascular and chronic inflammatory diseases. Therefore, the molecular mechanisms of the anti-inflammatory resveratrol effects deserve more attention. In human epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed32f2219dd6acc3f212443706440866
https://doi.org/10.1093/nar/gku1033
https://doi.org/10.1093/nar/gku1033
Autor:
Daniel Siuda, Hartmut Kleinert, Huige Li, Andrea Pautz, Matthias Oelze, Andreas Daiber, Jenny Henke, Ning Xia, Deborah J. Stumpo, Zhixiong Wu, Perry J. Blackshear, Franziska Bollmann
Publikováno v:
Journal of Biological Chemistry. 289:15653-15665
Cardiovascular events are important co-morbidities in patients with chronic inflammatory diseases like rheumatoid arthritis. Tristetraprolin (TTP) regulates pro-inflammatory processes through mRNA destabilization and therefore TTP-deficient mice (TTP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e44cf46c0d5d0be72bd1e05b363dfad
https://doi.org/10.1074/jbc.m114.566984
https://doi.org/10.1074/jbc.m114.566984
Autor:
Susanne Strand, Frank Schlufter, Gisela Reifenberg, Daniel Siuda, Hartmut Kleinert, Huige Li, Ning Xia, Ulrich Förstermann
Publikováno v:
Nitric oxide : biology and chemistry. 32
Many of the cardiovascular protective effects of resveratrol are attributable to an enhanced production of nitric oxide (NO) by the endothelial NO synthase (eNOS). Resveratrol has been shown to enhance eNOS gene expression as well as eNOS enzymatic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30f53c5722c4d76542a50219165221f
https://pubmed.ncbi.nlm.nih.gov/23583951
https://pubmed.ncbi.nlm.nih.gov/23583951