Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniel Silqueira Martins Guimarães"'
Autor:
Camila de Souza Barbosa, Daniel Silqueira Martins Guimarães, Alessandra Mirtes Marques Neves Gonçalves, Maria Cristina da Silva Barbosa, Marília Ladeira Alves e Costa, Clébio Soares Nascimento Júnior, Luciana Guimarães, Renato Márcio Ribeiro-Viana, Fabio Vieira dos Santos, Cristiana Ferreira Alves de Brito, Fernando de Pilla Varotti, Gustavo Henrique Ribeiro Viana
Publikováno v:
ACS Omega, Vol 2, Iss 11, Pp 8264-8272 (2017)
Externí odkaz:
https://doaj.org/article/ad1e9f18373247a6a0af8be35a028375
Autor:
Daniel Silqueira Martins Guimarães, Amanda Luisa da Fonseca, Ronan Batista, Moacyr Comar Junior, Alaíde Braga de Oliveira, Alex Gutterres Taranto, Fernando de Pilla Varotti
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 2, Pp 255-258 (2015)
Malaria is responsible for more deaths around the world than any other parasitic disease. Due to the emergence of strains that are resistant to the current chemotherapeutic antimalarial arsenal, the search for new antimalarial drugs remains urgent th
Externí odkaz:
https://doaj.org/article/27602856bae745f4b593006609999583
Autor:
Patrícia Ramos Gomes, Fábio Balbino Miguel, Michael Éder de Oliveira, Vanessa Viana Ferreira, Daniel Silqueira Martins Guimarães, Aline Brito de Lima, Camila de Souza Barbosa, Mariana Amorim de Oliveira, Mauro Vieira de Almeida, Gustavo Henrique Ribeiro Viana, Mara Rubia Costa Couri, Fernando de Pilla Varotti
Publikováno v:
Química Nova, Vol 37, Iss 3, Pp 492-496 (2014)
One of the main challenges in the development of new antimalarial drugs is to achieve a viable lead candidate with good pharmacokinetic properties. Curcumin has a broad range of biological activities, including antimalarial activity. Herein, we repor
Externí odkaz:
https://doaj.org/article/edb167f8cacc492499842d23fd2fa74d
Autor:
Gustavo Henrique Ribeiro Viana, Jéssica Ferreira Cardoso, Gisele Rodrigues da Silva, Fernando de Pilla Varotti, Marina Goulart da Silva, Daniel Silqueira Martins Guimarães, Renata Silva Mourão, Fernanda Barçante Perasoli, Renata Tupinambá Branquinho, Maria Luiza Costa Trench Xocaira, Harley Da Silva Tavares
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 151
Malaria treatment is based on a reduced number of antimalarial drugs, and drug resistance has emerged, leading to the search for new antimalarial drugs incorporated into pharmaceutical formulations. In this study, 10-(4,5-dihydrothiazol-2-yl)thio)dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5174b9f576cb3f2edceab2da2670e5c2
https://pubmed.ncbi.nlm.nih.gov/32470575
https://pubmed.ncbi.nlm.nih.gov/32470575
Autor:
Luciana Guimarães, Fábio Vieira dos Santos, Daniel Silqueira Martins Guimarães, Clébio Soares Nascimento Júnior, Alessandra Mirtes Marques Neves Gonçalves, Maria Cristina Da Silva Barbosa, Camila de Souza Barbosa, Cristiana Ferreira Alves de Brito, Renato Ribeiro-Viana, Fernando de Pilla Varotti, Marília Ladeira Alves e Costa, Gustavo Henrique Ribeiro Viana
Publikováno v:
ACS Omega, Vol 2, Iss 11, Pp 8264-8272 (2017)
ACS Omega
ACS Omega
The need to develop new alternatives for antimalarial treatment is urgent. Herein, we report the synthesis and antimalarial evaluation of a small library of synthetic 3-alkylpyridine marine alkaloid (3-APA) analogs. First, the compounds were evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a7df9269ff0c6d60c0d105ef91bca7
https://doaj.org/article/ad1e9f18373247a6a0af8be35a028375
https://doaj.org/article/ad1e9f18373247a6a0af8be35a028375
Autor:
Giovana de Almeida Pimentel, Daniel Silqueira Martins Guimarães, Fernando de Pilla Varotti, Maribel Navarro, Henrique Pereira, Adilson David da Silva, Juliane Aparecida Marinho, Izabelle Karine da Costa Nunes, Clarice Abramo, Nícolas Glanzmann
Publikováno v:
European Journal of Medicinal Chemistry. 215:113271
Chloroquine (CQ) has been the main treatment for malaria in regions where there are no resistant strains. Molecular hybridization techniques have been used as a tool in the search for new drugs and was implemented in the present study in an attempt t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2939b37787476dd16dcb735c31cc3493
https://doi.org/10.1016/j.ejmech.2021.113271
https://doi.org/10.1016/j.ejmech.2021.113271
Autor:
Ronan Batista, Moacyr Comar Junior, Amanda Luisa da Fonseca, Alex Gutterres Taranto, Fernando de Pilla Varotti, Alaíde Braga de Oliveira, Daniel Silqueira Martins Guimarães
Publikováno v:
Memórias do Instituto Oswaldo Cruz
Memórias do Instituto Oswaldo Cruz., Vol 110, Iss 2, Pp 255-258 (2015)
Memórias do Instituto Oswaldo Cruz, Volume: 110, Issue: 2, Pages: 255-258, Published: APR 2015
Memórias do Instituto Oswaldo Cruz., Vol 110, Iss 2, Pp 255-258 (2015)
Memórias do Instituto Oswaldo Cruz, Volume: 110, Issue: 2, Pages: 255-258, Published: APR 2015
Malaria is responsible for more deaths around the world than any other parasitic disease. Due to the emergence of strains that are resistant to the current chemotherapeutic antimalarial arsenal, the search for new antimalarial drugs remains urgent th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84ed69d7a54d4fee81cc73f8fbc14c3
http://europepmc.org/articles/PMC4489458
http://europepmc.org/articles/PMC4489458
Autor:
Gustavo Henrique Ribeiro Viana, Natália Rezende de Miranda Martins, Maria Cristina Da Silva Barbosa, Marília Ladeira Alves e Costa, Clebio S. Nascimento, Natália Chermont S. Moreira, Júlia Teixeira de Oliveira, Camila A. Caldeira, Fernando de Pilla Varotti, Daniel Silqueira Martins Guimarães, Fábio Vieira dos Santos, Gabrielle Kéfrem Alves Gomes, Camila de Souza Barbosa, Luciana Guimarães
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 825
Theonella sp is an important source of biologically-active 3-alkylpyridine alkaloids (3-APAs) that has shown a wide variety of promising biological effects. In the present work, two new 3-APAs analogues were synthesized based on molecular modeling st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e405e03fb864f602b1750b154f938e
https://pubmed.ncbi.nlm.nih.gov/29307373
https://pubmed.ncbi.nlm.nih.gov/29307373
Autor:
Sara Batista do Nascimento, Luciana Guimarães, Whocely Victor de Castro, Marina Goulart da Silva, Daniel Silqueira Martins Guimarães, Clébio Soares Nascimento Júnior, Vitória S. Reis, Anna Paola Butera, Alexandre Budu, Juliane Aparecida Marinho, Sarah El Chamy Maluf, Clarice Abramo, Natália Rezende de Miranda Martins, Fábio Vieira dos Santos, Adriana K. Carmona, Victor Matheus Kemmer, Cristiana Ferreira Alves de Brito, Letícia Silveira de Sousa Luz, Renato Ribeiro-Viana, Fernando de Pilla Varotti, Gisele Rodrigues da Silva, Heloísa Gonçalves de Almeida, Lorena Rabelo Silva, Gustavo Henrique Ribeiro Viana, Marcos L. Gazarini
Publikováno v:
European Journal of Pharmaceutical Sciences. 138:105015
The development of new antimalarial drugs is urgent to overcome the spread of resistance to the current treatment. Herein we synthesized the compound 3, a hit-to‑lead optimization of a thiazole based on the most promising 3-alkylpyridine marine alk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af227a1ca381a76f46e40591813891a
https://doi.org/10.1016/j.ejps.2019.105015
https://doi.org/10.1016/j.ejps.2019.105015
Autor:
Jaqueline Maria Siqueira Ferreira, Fabiana Pereira, Isabela Bacelar Assis, Eliana Maria Mauricio da Rocha, Glaécia A. N. Pereira, Emiliano Barreto, Daniel Silqueira Martins Guimarães
Publikováno v:
Pharmacognosy Magazine. 14:403
Background: Antibiotic resistance is a worldwide problem that poses a serious threat to human health, limiting the therapeutic options for bacterial infections. The spread of falciparum-resistant malaria is also concerning, making the patient treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18a4f0a855a5612a9d6446355d394530
https://doi.org/10.4103/pm.pm_273_17
https://doi.org/10.4103/pm.pm_273_17