Supplementary Figures from Clinical Response to a Lapatinib-Based Therapy for a Li-Fraumeni Syndrome Patient with a Novel HER2V659E Mutation

Autor: José Baselga, Joan Seoane, Maurizio Scaltriti, Paolo Nuciforo, Ludmila Prudkin, Joaquín Arribas, Javier Hernández-Losa, Judit Grueso, Leticia De Mattos-Arruda, Josep-Lluís Parra, Ginevra Caratù, Daniel Silberschmidt, Enriqueta Felip, Xose S. Puente, Ana Vivancos, Violeta Serra

Supplementary Figures - PDF file 585K, Supplementary Figure 1. Fluorescence in situ hybridization (FISH) of HER2. Supplementary Figure 2. EGFR and HER2 mutations identified. Supplementary Figure 3. Comparisons of allele frequencies. Supplementary Fig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ae505adb14b92ed9fa81e783d88ed5
https://doi.org/10.1158/2159-8290.22528592

Supplementary Tables S1-S15 from Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer

Autor: Héctor G. Palmer, Josep Tabernero, Wenlin Shao, Ana Vivancos, Paolo Nuciforo, Ramón Charco, Eloy Espín, Aleix Prat, Stefania Landolfi, Jordi Rodon, Daniel Silberschmidt, Judit Matito, Ginevra Caratù, Natalia Fernández, Rodrigo Dienstmann, Guillem Argilés, Stephan P. Tenbaum, Isabel Puig, Irene Chicote, Oriol Arqués

Supplementary Tables S1-S15. Table S1. Genes and positions analyzed by amplicon sequencing. Table S2. Genes sequenced by Haloplex Target Enrichment System. Table S3. Antibodies. Table S4. Treatment-induced apoptosis in 10 primary patient-derived sphe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cf6897db7daa06de70b36622bd3eb7
https://doi.org/10.1158/1078-0432.22460678.v1

Supporting Information from Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer

Autor: Héctor G. Palmer, Josep Tabernero, Wenlin Shao, Ana Vivancos, Paolo Nuciforo, Ramón Charco, Eloy Espín, Aleix Prat, Stefania Landolfi, Jordi Rodon, Daniel Silberschmidt, Judit Matito, Ginevra Caratù, Natalia Fernández, Rodrigo Dienstmann, Guillem Argilés, Stephan P. Tenbaum, Isabel Puig, Irene Chicote, Oriol Arqués

Supporting Information. Supplementary methods to complete the information for gene expression, genotyping, immunohistochemistry evaluation criteria and protein extraction. The file also contains legends for supplementary figures S1-S11 and supplement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2d4564148f69abe1a55a141bb75d80
https://doi.org/10.1158/1078-0432.22460675.v1

Conditional inactivation of the E-cadherin gene in thyroid follicular cells affects gland development but does not impair junction formation

Autor: Barbara D'Andrea, Günther Schütz, Lucio Nitsch, Tim M. Wintermantel, Oreda Boussadia, Roberto Di Lauro, Gaetano Calì, Rolf Kemler, Mariastella Zannini, Daniela Terracciano, Mario De Felice, Andrea Affuso, Daniel Silberschmidt, Elena Amendola, Patrizia Rubini, Carlo Tacchetti

Publikováno v: Endocrinology (Philadelphia) 148 (2007): 2737–2746. doi:10.1210/en.2006-1344
info:cnr-pdr/source/autori:Cali G, Zannini M, Rubini P, Tacchetti C, D'Andrea B, Affuso A, Wintermantel T, Boussadia O, Terracciano D, Silberschmidt D, Amendola E, De Felice M, Schutz G, Kemler R, Di Lauro R, Nitsch L./titolo:Conditional inactivation of the E-cadherin gene in thyroid follicular cells affects gland development but does not impair junction formation/doi:10.1210%2Fen.2006-1344/rivista:Endocrinology (Philadelphia)/anno:2007/pagina_da:2737/pagina_a:2746/intervallo_pagine:2737–2746/volume:148

We have conditionally inactivated the E-cadherin gene in the thyroid follicular cells of mouse embryo to unravel its role in thyroid development. We used the Cre-loxP system in which the Cre-recombinase was expressed under the control of the tissue-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27d5e36792bd18c8d8802965d408a55

Poly(3-Hydroxybutyrate) Synthesis Genes in Azotobacter sp. Strain FA8

Autor: Daniel Silberschmidt, M. Julia Pettinari, Gustavo J. Vazquez, Bernd H. A. Rehm, Beatriz S. Méndez, Alexander Steinbüchel

Genes responsible for the synthesis of poly(3-hydroxybutyrate) (PHB) in Azotobacter sp. FA8 were cloned and analyzed. A PHB polymerase gene ( phbC ) was found downstream from genes coding for β-ketothiolase ( phbA ) and acetoacetyl-coenzyme A reduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539f07f40e78bf0511c8c3535e14ad3a
https://europepmc.org/articles/PMC93310/