Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Daniel Shao-Weng Tan"'
Autor:
Janice Ser Huey Tan, Timothy Kwang Yong Tay, Enya Hui Wen Ong, Michael Fehlings, Daniel Shao-Weng Tan, Nadiah Binte Sukma, Eileen Xueqin Chen, Jen-Hwei Sng, Connie Siew Poh Yip, Kok Hing Lim, Darren Wan-Teck Lim, Narayanan Gopalakrishna Iyer, Jacqueline Siok Gek Hwang, Melvin Lee Kiang Chua, Mei-Kim Ang
Publikováno v:
European Thyroid Journal, Vol 13, Iss 1, Pp 1-10 (2024)
Objective: Anaplastic thyroid cancer (ATC) is an aggressive disease associated with poor outcomes and resistance to therapies. Our study aim was to evaluate the activity of a combinatorial regimen of sandwich sequencing of pembrolizumab immunotherapy
Externí odkaz:
https://doaj.org/article/bcbd473df09d426dac1f9589976fe55d
Autor:
Darren Wan-Teck Lim, Hsiang-Fong Kao, Lisda Suteja, Constance H. Li, Hong Sheng Quah, Daniel Shao-Weng Tan, Sze-Huey Tan, Eng-Huat Tan, Wan-Ling Tan, Justina Nadia Lee, Felicia Yu-Ting Wee, Amit Jain, Boon-Cher Goh, Melvin L. K. Chua, Bin-Chi Liao, Quan Sing Ng, Ruey-Long Hong, Mei-Kim Ang, Joe Poh-Sheng Yeong, N. Gopalakrishna Iyer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Single-agent checkpoint inhibitor (CPI) activity in Epstein-Barr Virus (EBV) related nasopharyngeal carcinoma (NPC) is limited. Dual CPI shows increased activity in solid cancers. In this single-arm phase II trial (NCT03097939), 40 patients
Externí odkaz:
https://doaj.org/article/9dac3f0d6a524296a18f65ed171dcbf2
Autor:
Abdul Rahman Jazieh, Huseyin Cem Onal, Daniel Shao-Weng Tan, Ross A. Soo, Kumar Prabhash, Amit Kumar, Reto Huggenberger, Byoung Chul Cho
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Tyrosine kinase inhibitors (TKIs) are the standard of care for resectable and metastatic non-small-cell lung cancer (NSCLC) harbouring epidermal growth factor receptor (EGFR) mutations (EGFRm). We describe the real-world practice of EGFRm
Externí odkaz:
https://doaj.org/article/346f0d01f55749cd9795ce7d7269daa2
Autor:
Joanna Hui Juan Tan, Say Li Kong, Joyce A. Tai, Huay Mei Poh, Fei Yao, Yee Yen Sia, Edwin Kok Hao Lim, Angela Maria Takano, Daniel Shao-Weng Tan, Asif Javed, Axel M. Hillmer
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 343-354 (2021)
Single cell genomics offers an unprecedented resolution to interrogate genetic heterogeneity in a patient’s tumour at the intercellular level. However, the DNA yield per cell is insufficient for today’s sequencing library preparation protocols. T
Externí odkaz:
https://doaj.org/article/19ec162017024374b03cd375a1fa8903
Autor:
Say Li Kong, Xingliang Liu, Swee Jin Tan, Joyce A. Tai, Ler Yee Phua, Huay Mei Poh, Trifanny Yeo, Yong Wei Chua, Yu Xuan Haw, Wen Huan Ling, Raymond Chee Hui Ng, Tira J. Tan, Kiley Wei Jen Loh, Daniel Shao-Weng Tan, Quan Sing Ng, Mei Kim Ang, Chee Keong Toh, Yi Fang Lee, Chwee Teck Lim, Tony Kiat Hon Lim, Axel M. Hillmer, Yoon Sim Yap, Wan-Teck Lim
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
IntroductionCirculating tumor cells (CTCs) and cell-free tumor DNA (ctDNA) are tumor components present in circulation. Due to the limited access to both CTC enrichment platforms and ctDNA sequencing in most laboratories, they are rarely analyzed tog
Externí odkaz:
https://doaj.org/article/b70ad78864ef47c3b413d596470674f7
Autor:
Srinivasaraghavan Kannan, Mohan R. Pradhan, Garima Tiwari, Wei-Chong Tan, Balram Chowbay, Eng Huat Tan, Daniel Shao-Weng Tan, Chandra Verma
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Small molecules targeting the EGFR tyrosine kinase domain have been used with some success at treating patients with non-small cell lung cancer driven by activating mutations in the kinase domain. The initial class of inhibitors displaced AT
Externí odkaz:
https://doaj.org/article/145a6170f8624c79b228e5d534e4ff3b
Autor:
Bee Luan Khoo, Majid Ebrahimi Warkiani, Daniel Shao-Weng Tan, Ali Asgar S Bhagat, Darryl Irwin, Dawn Pingxi Lau, Alvin S T Lim, Kiat Hon Lim, Sai Sakktee Krisna, Wan-Teck Lim, Yoon Sim Yap, Soo Chin Lee, Ross A Soo, Jongyoon Han, Chwee Teck Lim
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e99409 (2014)
BackgroundCirculating tumor cells (CTCs) are cancer cells that can be isolated via liquid biopsy from blood and can be phenotypically and genetically characterized to provide critical information for guiding cancer treatment. Current analysis of CTCs
Externí odkaz:
https://doaj.org/article/03951ce56787415fbd46f96bac1202e5
Autor:
Jun Ma, Sze Huey Tan, Daniel Xing Cheng Yin, Nguyen Tuan Anh Tran, Gek San Tan, Gillianne Geet Yi Lai, Mei-Kim Ang, Ravindran Kanesvaran, Amit Jain, Tanujaa Rajasekaran, Eng-Huat Tan, Tony Kiat Hon Lim, Daniel Shao-Weng Tan, Darren Wan-Teck Lim, Quan Sing Ng, Wan Ling Tan
Publikováno v:
Translational Lung Cancer Research. 12:742-753
Autor:
Stephanie Pei Li, Saw, Kevin Lee Min, Chua, Boon Hean, Ong, Darren Wan Teck, Lim, Gillianne Geet Yi, Lai, Daniel Shao Weng, Tan, Mei Kim, Ang
Publikováno v:
Annals of the Academy of Medicine, Singapore. 51:793-795
Autor:
Kumar Prabhash, Daniel Shao Weng Tan, Ross A. Soo, Piyada Sitthideatphaiboon, Yuh Min Chen, Pei Jye Voon, Elisna Syahruddin, Sojung Chu, Reto Huggenberger, Byoung-Chul Cho
Publikováno v:
Frontiers in Oncology. 13
IntroductionStage III non-small cell lung cancer (NSCLC) is a heterogeneous disease requiring multimodal treatment approaches. KINDLE-Asia, as part of a real world global study, evaluated treatment patterns and associated survival outcomes in stage I