Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Daniel Schimel"'
Autor:
Temeri Wilder-Kofie, Daniel L. Barber, Laura E. Via, M Sutphin, Juraj Kabat, Shunsuke Sakai, Keith D. Kauffman, Clifton E. Barry, Danielle M. Weiner, Olena Kamenyeva, Ian N. Moore, Daniel Schimel, Michelle A. Sallin, Rashida Moore
Publikováno v:
Mucosal immunology
Protection against Mycobacterium tuberculosis (Mtb) infection requires CD4 T cells to migrate into the lung and interact with infected macrophages. In mice, less-differentiated CXCR3+ CD4 T cells migrate into the lung and suppress growth of Mtb, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a7754b0bb230ead13629e2cc444628
https://doi.org/10.1038/mi.2017.60
https://doi.org/10.1038/mi.2017.60
Autor:
Véronique Dartois, Lori E. Dodd, Katherine K. Robbins, Danielle M. Weiner, Daniel Schimel, Clifton E. Barry, Kathleen England, Ray Y. Chen, Matthew D. Zimmerman, Dima A. Hammoud, JoAnne L. Flynn, Laura E. Via, Peter Herscovitch, Emmanuel Dayao, Mike Richardson, Ying Cai
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:4181-4189
Shortening the lengthy treatment duration for tuberculosis patients is a major goal of current drug development efforts. The common marmoset develops human-like disease pathology and offers an attractive model to better understand the basis for relap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4208851a5adfe979358cced88f0f8d7
https://doi.org/10.1128/aac.00115-15
https://doi.org/10.1128/aac.00115-15
Autor:
John D. Martin, Meenal Datta, Lei Xu, Clifton E. Barry, Rakesh K. Jain, Walid S. Kamoun, Wei Chen, Kathleen England, Laura E. Via, Daniel Schimel, Chong Liu, Danielle M. Weiner, Giorgio Seano, Xing Gao
Publikováno v:
Proceedings of the National Academy of Sciences. 112:1827-1832
Tuberculosis (TB) causes almost 2 million deaths annually, and an increasing number of patients are resistant to existing therapies. Patients who have TB require lengthy chemotherapy, possibly because of poor penetration of antibiotics into granuloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274a99f9cbf394ab1b01403af653efc4
https://doi.org/10.1073/pnas.1424563112
https://doi.org/10.1073/pnas.1424563112
Autor:
Kathleen England, Clifton E. Barry, Emmanuel Dayao, Daniel Schimel, Helena I. Boshoff, Laura E. Via, Danielle M. Weiner, Kriti Arora
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:3384-3387
The carbapenems imipenem and meropenem in combination with clavulanic acid reduced the bacterial burden in Mycobacterium tuberculosis -infected macrophages by 2 logs over 6 days. Despite poor stability in solution and a short half-life in rodents, tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b17e2c68baa65a9bbadddeeedf2009
https://doi.org/10.1128/aac.05690-11
https://doi.org/10.1128/aac.05690-11
Autor:
Richard Kvetnansky, Marcelino Bernardo, Peter L. Choyke, James F. Powers, Edwin W. Lai, Maria J. Merino, Daniel Schimel, Melanie Suzanne Kotys, Karel Pacak, J. Ruzicka, David Thomasson, Lucia Martiniova
Publikováno v:
Journal of Magnetic Resonance Imaging. 29:685-691
Purpose To compare contrast-enhanced micro-computed tomography (microCT) and nonenhanced respiratory-triggered magnetic resonance imaging (MRI) in an animal model of metastatic pheochromocytoma. Animal models are becoming important in the study of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5acd0d3279cfb9921f1d1863c0f4b4e
https://doi.org/10.1002/jmri.21654
https://doi.org/10.1002/jmri.21654
Autor:
Trinity J. Bivalacqua, Alan N. Schechter, Mark T. Gladwin, Lewis L. Hsu, Audrey E. Cochard, Xunde Wang, Daniel Schimel, Elizabeth A. Manci, Hunter C. Champion, Sally Campbell-Lee, Bhalchandra A. Diwan, Constance Tom Noguchi
Publikováno v:
Blood. 109:3088-3098
Pulmonary hypertension is a highly prevalent complication of sickle cell disease and is a strong risk factor for early mortality. However, the pathophysiological mechanisms by which sickle hemoglobin leads to pulmonary vasculopathy remain unclear. Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac5976025f1c82420455308f9979632
https://doi.org/10.1182/blood-2006-08-039438
https://doi.org/10.1182/blood-2006-08-039438
Autor:
Edwin W. Lai, Peter Guion, Karel Pacak, Shoichiro Ohta, Daniel Schimel, Elaine M. Jagoda, Brenda Klaunberg, Lucia Martiniova
Publikováno v:
Annals of the New York Academy of Sciences. 1073:392-404
This review focuses on anatomical (computed tomography, magnetic resonance imaging) and functional (positron emission tomography) imaging methods for tumor localization and identification of experimentally induced tumors in animal models, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3edb3cb1c245b5c4aca5f01c64daa9d
https://doi.org/10.1196/annals.1353.043
https://doi.org/10.1196/annals.1353.043
Autor:
Saher Lahouar, Sebastien Gagneux, Michael Tartakovsky, Praveen Paripati, Emmanuel Dayao, JoAnne L. Flynn, Laura E. Via, Ying Cai, Jaime Tomko, Alex Rosenthal, Philana Ling Lin, Seok Yong Eum, Sarah L. Tankersley, Damien Portevin, Danielle M. Weiner, Clifton E. Barry, Robin J. Kastenmayer, M. Teresa Coleman, Douglas B. Young, Daniel Schimel, Marlene Orandle
Publikováno v:
ResearcherID
Infection and immunity
Infection and immunity
Existing small-animal models of tuberculosis (TB) rarely develop cavitary disease, limiting their value for assessing the biology and dynamics of this highly important feature of human disease. To develop a smaller primate model with pathology simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf861aa0950316c4962871dede661ad6
https://europepmc.org/articles/PMC3719573/
https://europepmc.org/articles/PMC3719573/
Autor:
Clifton E. Barry, John D. Martin, Chong Liu, Daniel Schimel, Lei Xu, Wei Chen, Rakesh K. Jain, Laura E. Via, Giorgio Seano, Walid S. Kamoun, Danielle M. Weiner, Kathleen England, Meenal Datta, Xing Gao
Publikováno v:
Molecular Cancer Therapeutics. 14:B19-B19
Tuberculosis (TB) causes almost 2 million deaths annually, and an increasing number of patients are resistant to existing therapies. TB patients require lengthy chemotherapy, possibly because of poor penetration of antibiotics into granulomas where t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea3c14eb742950ee90bf7f3fb692b333
https://doi.org/10.1158/1538-8514.tumang15-b19
https://doi.org/10.1158/1538-8514.tumang15-b19
Autor:
Tatyana Chanturiya, Lewis L. Hsu, Oksana Gavrilova, Dena R. Yver, Lynne Hugendubler, Elisabetta Mueller, Selin Mammen, Daniel Schimel, Norio Suzuki, Samuel W. Cushman, Constance Tom Noguchi, Ruifeng Teng, Masayuki Yamamoto
Publikováno v:
Nature communications
While erythropoietin is the cytokine known that regulates erythropoiesis, erythropoietin receptor (EpoR) expression and associated activity beyond hematopoietic tissue remain uncertain. Here we show that mice with EpoR expression restricted to hemato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041fa69404d2b7c718b4b2df305d6331
https://doi.org/10.1038/ncomms1526
https://doi.org/10.1038/ncomms1526