Zobrazeno 1 - 10 of 54 pro vyhledávání: '"Daniel S. Strasser"'
1
Akademický článek
Quantification of increased biologically active CXCL12α plasma concentrations after ACKR3 antagonist treatment in humans
Autor: Peter Blattmann, Hervé Farine, Brian Dan, Nicole Stiffler, Thomas Lefebvre, Christine Huynh, Patricia N. Sidharta, Jasper Dingemanse, Richard W. D. Welford, Marcel Keller, Daniel S. Strasser
Publikováno v: Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract CXCL12 acts as a chemoattractant by binding to the receptor CXCR4. The (atypical) chemokine receptor ACKR3 (CXCR7) scavenges CXCL12. Antagonism of ACKR3 thus leads to an increase in CXCL12 concentrations that has been used as a pharmacodynam
Externí odkaz: https://doaj.org/article/e53b8c21584147f092daf12cfbcb0485
Zobrazit plný text záznamu
2
Akademický článek
Plasma neurofilament light, glial fibrillary acidic protein and lysosphingolipid biomarkers for pharmacodynamics and disease monitoring of GM2 and GM1 gangliosidoses patients
Autor: Richard W.D. Welford, Herve Farine, Michel Steiner, Marco Garzotti, Kostantin Dobrenis, Claudia Sievers, Daniel S. Strasser, Yasmina Amraoui, Peter M.A. Groenen, Roberto Giugliani, Eugen Mengel
Publikováno v: Molecular Genetics and Metabolism Reports, Vol 30, Iss , Pp 100843- (2022)
GM2 and GM1 gangliosidoses are genetic, neurodegenerative lysosomal sphingolipid storage disorders. The earlier the age of onset, the more severe the clinical presentation and progression, with infantile, juvenile and late-onset presentations broadly
Externí odkaz: https://doaj.org/article/2598cb3f1138405aab2f37467293894f
Zobrazit plný text záznamu
3
Akademický článek
CXCR7 Antagonism Reduces Acute Lung Injury Pathogenesis
Autor: Laetitia Pouzol, Anna Sassi, Nadège Baumlin, Mélanie Tunis, Daniel S. Strasser, François Lehembre, Marianne M. Martinic
Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Loss of control in the trafficking of immune cells to the inflamed lung tissue contributes to the pathogenesis of life-threatening acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS). Targeting CXCR7 has been
Externí odkaz: https://doaj.org/article/87143f960dcd406b842cdbeee31d0c1a
Zobrazit plný text záznamu
6
A Multipurpose First‐in‐Human Study With the Novel CXCR7 Antagonist ACT‐1004‐1239 Using CXCL12 Plasma Concentrations as Target Engagement Biomarker
Autor: Mohamed Al-Ibrahim, Christine Huynh, Mike Ufer, Daniel S. Strasser, Andrea Henrich, Henriette E. Meyer zu Schwabedissen, Marie-Laure Boof, Jasper Dingemanse
Publikováno v: Clinical Pharmacology & Therapeutics. 109:1648-1659
The C-X-C chemokine receptor 7 (CXCR7) has evolved as a promising, druggable target mainly in the immunology and oncology fields modulating plasma concentrations of its ligands CXCL11 and CXCL12 through receptor-mediated internalization. This "scaven
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db19a71912a09be7aef772135c84cad
https://doi.org/10.1002/cpt.2154
Zobrazit plný text záznamu
7
Catalysts and motivations for change in privacy coordination: transracial, internationally adoptive parents’ coordination of private, adoption-related information
Autor: Michele D. Hanna, Elizabeth A. Suter, Mary Claire Morr Loftus, Daniel S. Strasser
Publikováno v: Communication Quarterly. 69:1-22
Communication Privacy Management theory (CPM) was applied in a qualitative analysis of survey responses from parents in transracial, internationally adoptive families concerning their management of...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d6933882ffa8c661fc13ab2641ca689
https://doi.org/10.1080/01463373.2020.1864428
Zobrazit plný text záznamu
9
CXCR7 Antagonism Reduces Acute Lung Injury Pathogenesis
Autor: Mélanie Tunis, Anna Sassi, Nadège Baumlin, Daniel S. Strasser, François Lehembre, Laetitia Pouzol, Marianne M Martinic
Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Loss of control in the trafficking of immune cells to the inflamed lung tissue contributes to the pathogenesis of life-threatening acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS). Targeting CXCR7 has been
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57748fd6831f3f9a4814f72a30d55a6
https://doi.org/10.3389/fphar.2021.748740
Zobrazit plný text záznamu
10
Pharmacological Characterization of Aprocitentan, a Dual Endothelin Receptor Antagonist, Alone and in Combination with Blockers of the Renin Angiotensin System, in Two Models of Experimental Hypertension
Autor: Ulrich Mentzel, Markus Kramberg, Marc Iglarz, Enrico Vezzali, Frederic Trensz, Céline Bortolamiol, Daniel Wanner, Stephane Delahaye, Hakim Hadana, Daniel S. Strasser, Patrick Hess, Markus Rey, Joël Ménard, Martine Clozel
Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 368:462-473
The endothelin (ET) system has emerged as a novel target for hypertension treatment where a medical need persists despite availability of several pharmacological classes, including renin angiotensin system (RAS) blockers. ET receptor antagonism has d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d32d8d86285b9758185f4b07108c406
https://doi.org/10.1124/jpet.118.253864
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje