Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Daniel S. Kessler"'
Autor:
Mahak Sharma, Victoria M Larow, Nataliia Dobychina, Daniel S Kessler, Maria M Krasilnikova, Sergey Yaklichkin
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0296176 (2023)
Forkhead box E1 (FoxE1) protein is a transcriptional regulator known to play a major role in the development of the thyroid gland. By performing sequence alignments, we detected a deletion in FoxE1, which occurred in the evolution of mammals, near th
Externí odkaz:
https://doaj.org/article/56b4bfd1450d417d8b101a4a436d5649
Autor:
Sergey Yaklichkin, Qun Lu, Shouwen Wang, Christine D. Reid, Daniel S. Kessler, Aaron B. Steiner, Morgan Hennessy
Publikováno v:
Developmental biology. 414(1)
In the vertebrate blastula and gastrula the Nodal pathway is essential for formation of the primary germ layers and the organizer. Nodal autoregulatory feedback potentiates signaling activity, but mechanisms limiting embryonic Nodal ligand transcript
Publikováno v:
Developmental Biology. 352:367-381
The Spemann organizer is an essential signaling center in Xenopus germ layer patterning and axis formation. Organizer formation occurs in dorsal blastomeres receiving both maternal Wnt and zygotic Nodal signals. In response to stabilized βcatenin, d
Autor:
Daniel S. Kessler, Lisa L. Chang
Publikováno v:
Developmental Biology. 342(1):39-50
Establishment of the embryonic mesoderm is dependent on integration of multiple signaling and transcriptional inputs. We report that the transcriptional regulator Foxd3 is essential for dorsal mesoderm formation in zebrafish, and that this function i
Publikováno v:
Journal of Biological Chemistry. 282:2548-2557
FoxD3 is a forkhead-related transcriptional regulator that is essential for multiple developmental processes in the vertebrate embryo, including neural crest development and maintenance of mammalian stem cell lineages. Recent results demonstrate a re
Autor:
Sergey Yaklichkin, Julie L. Lefebvre, Aaron B. Steiner, Eileen Piwarzyk, Mark J. Engleka, Patricia A. Labosky, Liliam Pineda-Salgado, Daniel S. Kessler, James Walters, Qun Lu
Publikováno v:
Development. 133:4827-4838
Induction and patterning of the mesodermal germ layer is a key early step of vertebrate embryogenesis. We report that FoxD3 function in the Xenopus gastrula is essential for dorsal mesodermal development and for Nodal expression in the Spemann organi
Autor:
Charles P. Emerson, Stephen D. Freeman, Xingbin Ai, Shouwen Wang, Qun Lu, Daniel S. Kessler, Mary Elizabeth Pownall
Publikováno v:
Proceedings of the National Academy of Sciences. 101:4833-4838
The signaling activities of multiple developmental ligands require sulfated heparan sulfate (HS) proteoglycans as coreceptors. QSulf1 and its mammalian orthologs are cell surface HS 6- O -endosulfatases that are expressed in embryonic mesodermal and
Publikováno v:
Genes & Development. 16:2650-2661
Critical to our understanding of the developmental potential of stem cells and subsequent control of their differentiation in vitro and in vivo is a thorough understanding of the genes that control stem cell fate. Here, we report that Foxd3, a member
Publikováno v:
Developmental Biology. 240:377-386
VegT is an essential maternal regulator of germ layer specification in Xenopus. The localization of VegT mRNA to the vegetal cortex of the oocyte during oogenesis ensures its inheritance by vegetal and not animal cells, and directs the differentiatio
Autor:
Frank L. Conlon, Daniel S. Kessler
Publikováno v:
Trends in Genetics. 16:537-540