Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daniel S. Catlin"'
Autor:
Richard B. Silverman, Peter F. Doubleday, Neil L. Kelleher, Timothy A Dwight, Arseniy Butrin, Daniel S. Catlin, Pathum M. Weerawarna, Dali Liu, Rafael D. Melani, Wei Zhu
Publikováno v:
Journal of the American Chemical Society. 143:8193-8207
Human ornithine aminotransferase (hOAT) is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that was recently found to play an important role in the metabolic reprogramming of hepatocellular carcinoma (HCC) via the proline and glutamine metabolic path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a259ccd297ef27998383e601be90b8d4
https://doi.org/10.1021/jacs.1c03572
https://doi.org/10.1021/jacs.1c03572
Autor:
Peter F. Doubleday, Neil L. Kelleher, Daniel S. Catlin, Richard B. Silverman, Dali Liu, Matthew J. Moschitto
Publikováno v:
Journal of the American Chemical Society. 141:10711-10721
The inhibition of ornithine aminotransferase (OAT), a pyridoxal 5'-phosphate-dependent enzyme, has been implicated as a treatment for hepatocellular carcinoma (HCC), the most common form of liver cancer, for which there is no effective treatment. Fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8f34cfb5aa06fbd3b0a8b4d8f797467
https://doi.org/10.1021/jacs.9b03254
https://doi.org/10.1021/jacs.9b03254
Autor:
Wei, Zhu, Peter F, Doubleday, Arseniy, Butrin, Pathum M, Weerawarna, Rafael D, Melani, Daniel S, Catlin, Timothy A, Dwight, Dali, Liu, Neil L, Kelleher, Richard B, Silverman
Publikováno v:
J Am Chem Soc
Human ornithine aminotransferase (hOAT) is a pyridoxal 5′-phosphate (PLP)-dependent enzyme that was recently found to play an important role in the metabolic reprogramming of hepatocellular carcinoma (HCC) via proline and glutamine metabolic pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32d854c7d31daa2ee3c549e9e7f28268
https://pubmed.ncbi.nlm.nih.gov/34014654
https://pubmed.ncbi.nlm.nih.gov/34014654
Autor:
Rachel M. Bleich, Jonathan W. Bogart, Aneta Turlik, R. Thomas Williamson, Daniel S. Catlin, Albert A. Bowers, Frank C. Schroeder, Nicholas J. Kramer, Satish K. Nair, K. N. Houk
Publikováno v:
J Am Chem Soc
Thiopeptides are a broad class of macrocyclic, heavily modified peptide natural products that are unified by the presence of a substituted, nitrogen-containing heterocycle core. Early work indicated that this core might be fashioned from two dehydroa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3e6702c677c651de4b951f83d72031
https://pubmed.ncbi.nlm.nih.gov/32609512
https://pubmed.ncbi.nlm.nih.gov/32609512
Autor:
Daniel S. Catlin, Thomas R. Trzupek, Daniel P. Becker, Brian L Cannon, Cory T. Reidl, Richard B. Silverman, Dali Liu
Publikováno v:
Protein Sci
Addressing molecular recognition in the context of evolution requires pursuing new molecular targets to enable the development of agonists or antagonists with new mechanisms of action. Disruption of transcriptional regulation through targeting transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b51c196951179646ffc0b9a559c563
https://pubmed.ncbi.nlm.nih.gov/32557944
https://pubmed.ncbi.nlm.nih.gov/32557944
Publikováno v:
J Biol Chem
Cleavage of aromatic carbon–chlorine bonds is critical for the degradation of toxic industrial compounds. Here, we solved the X-ray crystal structure of chlorothalonil dehalogenase (Chd) from Pseudomonas sp. CTN-3, with 15 of its N-terminal residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7baec14ea6e2123c03b30732ec94ef
https://europepmc.org/articles/PMC7324493/
https://europepmc.org/articles/PMC7324493/
Autor:
Matthew J, Moschitto, Peter F, Doubleday, Daniel S, Catlin, Neil L, Kelleher, Dali, Liu, Richard B, Silverman
Publikováno v:
J Am Chem Soc
The inhibition of ornithine aminotransferase (OAT), a pyridoxal 5′-phosphate-dependent enzyme, has been implicated as a treatment for hepatocellular carcinoma (HCC), the most common form of liver cancer, for which there is no effective treatment. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a917125c9684c4136251ef4629c62534
https://pubmed.ncbi.nlm.nih.gov/31251613
https://pubmed.ncbi.nlm.nih.gov/31251613
Autor:
Neil L. Kelleher, Rui Wu, Eric J. Drake, Walter Fast, Dali Liu, Andrew M. Gulick, Kenneth D. Clevenger, Romila Mascarenhas, Daniel S. Catlin
Publikováno v:
ACS chemical biology. 12(3)
Siderophore biosynthesis by Pseudomonas aeruginosa enhances virulence and represents an attractive drug target. PvdQ functions in the type-1 pyoverdine biosynthetic pathway by removing a myristoyl anchor from a pyoverdine precursor, allowing eventual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799e2f74a15f8f8128748bcf950d9743
https://pubmed.ncbi.nlm.nih.gov/28186406
https://pubmed.ncbi.nlm.nih.gov/28186406