Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors

Autor: Ye Chen, Joanne M. L. Ho, David L. Shis, Chinmaya Gupta, James Long, Daniel S. Wagner, William Ott, Krešimir Josić, Matthew R. Bennett

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)

For synthetic gene circuits to behave as designed, ligand-inducible promoters should display predictable ON/OFF characteristics. Here the authors design multi-input hybrid promoters to build transcriptional logic gates.

Externí odkaz: https://doaj.org/article/9f191ec1c7d248d3bde26396083e9a7b

Rethinking Human Embryo Research Policies

Autor: Jochen Taupitz, Matteo A. Molè, Jason Scott Robert, Nuria Gallego Marquez, Marieke Bigg, Sarah Franklin, Daniel S. Wagner, Søren Holm, Giuseppe Testa, Ana S. Iltis, Inmaculada de Melo-Martín, Ingrid Metzler, Jeremy Sugarman, Kirstin R.W. Matthews

Publikováno v: The Hastings Center Report
Matthews, K R W, Iltis, A S, Marquez, N G, Wagner, D S, Robert, J S, de Melo-Martín, I, Bigg, M, Franklin, S, Holm, S, Metzler, I, Molè, M A, Taupitz, J, Testa, G & Sugarman, J 2021, ' Rethinking Human Embryo Research Policies ', The Hastings Center report, vol. 51, no. 1, pp. 47-51 . https://doi.org/10.1002/hast.1215

It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee80719c88bf504b2f7648d8d698a34
https://doi.org/10.1002/hast.1215

Surgical debridement of infected pubic symphysitis supports optimal outcome

Autor: Pol Maria Rommens, Johannes Christof Hopf, Benjamin Devlieger, Daniel S. Wagner

Publikováno v: Archives of Orthopaedic and Trauma Surgery

IntroductionInfected pubic symphysitis (IPS) is a rare bacterial infection of the pubic symphysis that causes subpubic pain, disability and ultimately permanent immobility. Due to difficult diagnosis, patients present with long-standing complaints an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01491e7185b33504fc923664f9d7f983

Artificial intelligence and CT-based 3D statistical modeling to assess transsacral corridors and plan implant positioning

Autor: Charlotte Arand, Kristin Handrich, Daniel S. Wagner, Lukas Kamer, Hansrudi Noser, Pol Maria Rommens

Transsacral corridors at levels S1 and S2 represent complex osseous spaces allowing percutaneous fixation of non- or minimally-displaced fragility fractures of the sacrum. To safely place transsacral implants, they must be completely intraosseous. Ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52758cddc43477a8d52352c2fbc74096

Computer tomographic analysis of anatomic characteristics of the ulna - essential parameters for preshaped implants

Autor: Johannes Christof Hopf, Daniel S. Wagner, Ruben Sebastian Westphal, Pol Maria Rommens, Tobias Jorg, Andreas Jähnig

Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 5, p e0232988 (2020)

PURPOSE:Anatomically preshaped implants are needed for exact restoration of the anatomy after fractures of the proximal ulna and ulnar shaft, which enables a good functional outcome. Aim of this computed tomographic analysis was to identify specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3b69d94c0b41b6a0ef2f2058e05ecd
https://pubmed.ncbi.nlm.nih.gov/32437353