Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Daniel S Terry"'
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008293 (2020)
Molecular Dynamics (MD) simulations seek to provide atomic-level insights into conformationally dynamic biological systems at experimentally relevant time resolutions, such as those afforded by single-molecule fluorescence measurements. However, limi
Externí odkaz:
https://doaj.org/article/db0e0fee946d461b8734df83c9cbea39
Autor:
Xiaochu Ma, Maolin Lu, Jason Gorman, Daniel S Terry, Xinyu Hong, Zhou Zhou, Hong Zhao, Roger B Altman, James Arthos, Scott C Blanchard, Peter D Kwong, James B Munro, Walther Mothes
Publikováno v:
eLife, Vol 7 (2018)
HIV-1 entry into cells requires binding of the viral envelope glycoprotein (Env) to receptor CD4 and coreceptor. Imaging of individual Env molecules on native virions shows Env trimers to be dynamic, spontaneously transitioning between three distinct
Externí odkaz:
https://doaj.org/article/ac15869e948c47c2b1fd101eeab5a88a
Autor:
Jesper Levring, Daniel S. Terry, Zeliha Kilic, Gabriel Fitzgerald, Scott C. Blanchard, Jue Chen
Publikováno v:
Nature. 616:606-614
The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel that regulates salt and fluid homeostasis across epithelial membranes1. Alterations in CFTR cause cystic fibrosis, a fatal disease without a cure2,3. Electrophysiologi
Autor:
Jesper Levring, Daniel S. Terry, Zeliha Kilic, Gabriel Fitzgerald, Scott C. Blanchard, Jue Chen
Publikováno v:
Nature. 617:E11-E11
Autor:
Michael D. Holsey, Grant T. Gilmore, Adam W. Smith, Jonathan A. Javitch, Avik Kumar Pati, Kaleeckal G. Harikumar, Zhou Zhou, Jozsef Meszaros, Laurence J. Miller, Khuloud Jaqaman, Peter Geggier, Signe Mathiasen, Wesley B. Asher, Megan J. Kaliszewski, Mitchell D. McCauley, Scott C. Blanchard, Daniel S. Terry, Alekhya Govindaraju
Publikováno v:
Nature Methods. 18:397-405
Class C G protein-coupled receptors (GPCRs) are known to form stable homodimers or heterodimers critical for function, but the oligomeric status of class A and B receptors, which constitute >90% of all GPCRs, remains hotly debated. Single-molecule fl
Autor:
Peter D. Kwong, Brennan P. Carman, Andrés Finzi, Dongjun Peng, Walther Mothes, Daniel S. Terry, Joseph Sodroski, Amos B. Smith, Baoshan Zhang, Cameron F. Abrams, Jason Gorman, Michael Farzan, Nick Reichard, Maolin Lu, Utz Ermel, Tongqing Zhou, Luis R. Castillo-Menendez, Akihiro Sugawara, Kevin Wang, Jonathan R. Grover, James Arthos, Scott C. Blanchard, James B. Munro, Michael Chambers, Adrian B. McDermott, Ivana Nikić-Spiegel, Edward A. Lemke, Xiaochu Ma, Matthew R. Gardner, Nirmin Alsahafi
Publikováno v:
Nature
The HIV-1 envelope glycoprotein (Env) trimer mediates cell entry and is conformationally dynamic1-8. Imaging by single-molecule fluorescence resonance energy transfer (smFRET) has revealed that, on the surface of intact virions, mature pre-fusion Env
Autor:
Daniel S. Terry, Scott C. Blanchard, Changhao He, Xiaoyu Wang, Gabriel A. Fitzgerald, Olga Boudker, Didar Ciftci, Gerard H. M. Huysmans, Zhou Zhou
Publikováno v:
Bio Protoc
Secondary active transporters reside in cell membranes transporting polar solutes like amino acids against steep concentration gradients, using electrochemical gradients of ions as energy sources. Commonly, ensemble-based measurements of radiolabeled
Autor:
Scott C. Blanchard, Andrés Finzi, Wei Shi, Peter D. Kwong, Guillaume Beaudoin-Bussières, John R. Mascola, Walther Mothes, Annemarie Laumaea, Romain Gasser, Daniel S. Terry, Wenwei Li, Desheng Zheng, Lihong Liu, Sai Priya Anand, David D. Ho, Jérémie Prévost, Tongqing Zhou, Jason Gorman, Maolin Lu, Jonathan R. Grover, Shilei Ding, Pradeep D. Uchil, Baoshan Zhang
Publikováno v:
Cell Host & Microbe
bioRxiv
bioRxiv
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) mediates viral entry into cells and is critical for vaccine development against coronavirus disease 2019 (COVID-19). Structural studies have revealed distinct conformations of
Autor:
Walther Mothes, Daniel S. Terry, Nick Reichard, Joseph Sodroski, James Arthos, Scott C. Blanchard, Xiaochu Ma, Amos B. Smith, Maolin Lu
Publikováno v:
J Virol
The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) trimer of gp120-gp41 heterodimers mediates virus entry into CD4-positive (CD4(+)) cells. Single-molecule fluorescence resonance energy transfer (smFRET) has revealed that nat
Autor:
Walther Mothes, Baoshan Zhang, Peter D. Kwong, Wenwei Li, Julian W. Bess, Ze Li, Cara W. Chao, Jason Gorman, Maolin Lu, Jeffrey D. Lifson, Jun Liu, Tongqing Zhou, Daniel S. Terry, Scott C. Blanchard
Publikováno v:
Nat Struct Mol Biol
The HIV-1 envelope glycoprotein (Env) trimer, composed of gp120 and gp41 subunits, mediates viral entry into cells. Recombinant Env trimers have been studied structurally, but characterization of Env embedded in intact virus membranes has been limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72365854287c4ea97477f02ada6add4
https://europepmc.org/articles/PMC8138683/
https://europepmc.org/articles/PMC8138683/