Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Daniel S Matasic"'
Autor:
James Osei-Owusu, Zheng Ruan, Ljubica Mihaljević, Daniel S Matasic, Kevin Hong Chen, Wei Lü, Zhaozhu Qiu
Publikováno v:
eLife, Vol 11 (2022)
Desensitization is a common property of membrane receptors, including ion channels. The newly identified proton-activated chloride (PAC) channel plays an important role in regulating the pH and size of organelles in the endocytic pathway, and is also
Externí odkaz:
https://doaj.org/article/b71011fe8a844ef9b81177660edfc2f7
Autor:
Jared M. McLendon, Xiaoming Zhang, Daniel S. Matasic, Mohit Kumar, Olha M. Koval, Isabella M. Grumbach, Sakthivel Sadayappan, Barry London, Ryan L. Boudreau
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 13 (2022)
Background Sorbin and SH3 domain containing 2 (Sorbs2) protein is a cytoskeletal adaptor with an emerging role in cardiac biology and disease; yet, its potential relevance to adult‐onset cardiomyopathies remains underexplored. Sorbs2 global knockou
Externí odkaz:
https://doaj.org/article/b196424fa3644aaaa2ddb79eeca7f516
Autor:
Daniel S. Matasic, Nicholas Holland, Mamta Gautam, David D. Gibbons, Nobuyoshi Kusama, Anne M. S. Harding, Viral S. Shah, Peter M. Snyder, Christopher J. Benson
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Acid-Sensing Ion Channels (ASICs) are proton-gated sodium-selective cation channels that have emerged as metabolic and pain sensors in peripheral sensory neurons and contribute to neurotransmission in the CNS. These channels and their related degener
Externí odkaz:
https://doaj.org/article/cd23ab496edd4a32b8854ec131e66282
Autor:
Jin-Young Yoon, Alexander M. Greiner, Julia S. Jacobs, Young-Rae Kim, William Kutschke, Daniel S. Matasic, Ajit Vikram, Ravinder R Gaddam, Haider Mehdi, Kaikobad Irani, Barry London
BackgroundDecreased peak sodium current (INa) and increased late sodium current (INa,L), through the cardiac sodium channel NaV1.5 encoded bySCN5A, cause arrhythmias. Many NaV1.5 post-translational modifications have been reported by us and others. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3c74438d44848f7213cdfb6c722b34a
https://doi.org/10.1101/2022.12.26.521675
https://doi.org/10.1101/2022.12.26.521675
Publikováno v:
Biophysical Journal. 122:458a-459a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d9746f25789b2406adbdcd20c2eb39f
https://doi.org/10.1016/j.bpj.2022.11.2465
https://doi.org/10.1016/j.bpj.2022.11.2465
Autor:
Zheng Ruan, James Osei-Owusu, Ljubica Mihaljević, Daniel S Matasic, Kevin Hong Chen, Wei Lü, Zhaozhu Qiu
Publikováno v:
eLife. 11
Desensitization is a common property of membrane receptors, including ion channels. The newly identified proton-activated chloride (PAC) channel plays an important role in regulating the pH and size of organelles in the endocytic pathway, and is also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec581627eeaa3603e1b6b7f57c677657
https://pubmed.ncbi.nlm.nih.gov/36547405
https://pubmed.ncbi.nlm.nih.gov/36547405
Autor:
Gina M. Morgan, Mark S. Schmidt, Haider Mehdi, Jared M. McLendon, Ryan L. Boudreau, Alexander M. Greiner, Pravda Quinones, Jin-Young Yoon, Daniel S. Matasic, Barry London, Charles Brenner, Kaikobad Irani
Publikováno v:
J Mol Cell Cardiol
RationaleThe cardiac sodium channel NaV1.5, encoded by SCN5A, produces the rapidly inactivating depolarizing current INa that is responsible for the initiation and propagation of the cardiac action potential. Acquired and inherited dysfunction of NaV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d090e7eb0a9fac5899be64d80c8df2
https://doi.org/10.1016/j.yjmcc.2020.01.013
https://doi.org/10.1016/j.yjmcc.2020.01.013
Autor:
Jin-young Yoon, Alexander Greiner, Julia Jacobs, William J Kutschke, Young-Rae Kim, Daniel S Matasic, Haider Mehdi, Kaikobad J Irani, Barry London
Publikováno v:
Circulation. 144
Introduction: The sodium current (I Na ) controlling cardiac cell excitability is conducted via the Na + channel Na V 1.5 (encoded by SCN5A ). Dysregulation of Na V 1.5 has been implicated in arrhythmia, with increased late Na V 1.5 current (I Na,L )
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3d77f590746be7fbed25a0d07dd958
https://doi.org/10.1161/circ.144.suppl_1.14053
https://doi.org/10.1161/circ.144.suppl_1.14053
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 314:H839-H852
Nicotinamide adenine dinucleotide (NAD+) and related metabolites are central mediators of fuel oxidation and bioenergetics within cardiomyocytes. Additionally, NAD+is required for the activity of multifunctional enzymes, including sirtuins and poly(A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8c24ba028e138cfb9f8352c4738088
https://doi.org/10.1152/ajpheart.00409.2017
https://doi.org/10.1152/ajpheart.00409.2017