Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Daniel S Kong"'
Autor:
Ryan M. Baxter, Christine S. Wang, Josselyn E. Garcia-Perez, Daniel S. Kong, Brianne M. Coleman, Valentyna Larchenko, Ronald P. Schuyler, Conner Jackson, Tusharkanti Ghosh, Pratyaydipta Rudra, Debdas Paul, Manfred Claassen, Rosemary Rochford, John C. Cambier, Debashis Ghosh, Jennifer C. Cooper, Mia J. Smith, Elena W. Y. Hsieh
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMost childhood-onset SLE patients (cSLE) develop lupus nephritis (cLN), but only a small proportion achieve complete response to current therapies. The prognosis of children with LN and end-stage renal disease is particularly dire. Mortal
Externí odkaz:
https://doaj.org/article/a41397a204e54b1f9e4f77656d9bf4c0
Autor:
Zachary R. Zottola, Daniel S. Kong, Ankit N. Medhekar, Lauren E. Frye, Scarlett B. Hao, Dakota W. Gonring, Adnan A. Hirad, Michael C. Stoner, Michael S. Richards, Doran S. Mix
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionCurrent abdominal aortic aneurysm (AAA) assessment relies on analysis of AAA diameter and growth rate. However, evidence demonstrates that AAA pathology varies among patients and morphometric analysis alone is insufficient to precisely pr
Externí odkaz:
https://doaj.org/article/8d3fbb9b78024c3e98a74dfdeb8405f0
Autor:
Josselyn E. Garcia-Perez, Ryan M. Baxter, Daniel S. Kong, Richard Tobin, Martin McCarter, John M. Routes, James Verbsky, Michael B. Jordan, Cullen M. Dutmer, Elena W. Y. Hsieh
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CTLA-4 is essential for immune tolerance. Heterozygous CTLA4 mutations cause immune dysregulation evident in defective regulatory T cells with low levels of CTLA-4 expression. Biallelic mutations in LRBA also result in immune dysregulation with low l
Externí odkaz:
https://doaj.org/article/c80be548f8aa430a82d406e1f50aadde
Autor:
Victor G. Lui, Tusharkanti Ghosh, Amy Rymaszewski, Shaoying Chen, Ryan M. Baxter, Daniel S. Kong, Debashis Ghosh, John M. Routes, James W. Verbsky, Elena W. Y. Hsieh
Publikováno v:
Journal of Clinical Immunology.
Autor:
Zachary R, Zottola, Joel L, Kruger, Daniel S, Kong, Karina A, Newhall, Adam J, Doyle, Doran S, Mix, Michael C, Stoner
Publikováno v:
Journal of vascular surgery.
It has been shown local or regional anesthetic techniques are a feasible alternative to general anesthesia for endovascular aortic aneurysm repair (EVAR). However, studies to date have shown controversial findings with respect to the benefit of local
Autor:
Rosemary Rochford, Hesham Eissa, Ryan M Baxter, Jennifer O. Black, James C. Gumbart, Ralph Quinones, Cullen M. Dutmer, Isabel Z. Fernandez, Judith R. Kelsen, Michael R. Verneris, Ross M. Kedl, Thanmayi Ranganath, Noor Dawany, Daniel S Kong, Karl Lundquist, Josselyn E Garcia-Perez, Edwin F. de Zoeten, Tom C. Nguyen, Csaba Galambos, Elena Vendrame, Elena W Y Hsieh, Kathleen E. Sullivan, Sidney Ogolla, Catherine A. Blish
Publikováno v:
Journal of Experimental Medicine. 216:1255-1267
The pleiotropic actions of interleukin-2 (IL-2) are essential for regulation of immune responses and maintenance of immune tolerance. The IL-2 receptor (IL-2R) is composed of IL-2Rα, IL-2Rβ, and IL-2Rγ subunits, with defects in IL-2Rα and IL-2Rγ
Autor:
Daniel S, Kong, Mark D, Balceniuk, Doran, Mix, Jennifer L, Ellis, Adam J, Doyle, Roan J, Glocker, Michael C, Stoner
Publikováno v:
Journal of Vascular Surgery. 76:437-444.e2
Within the context of endovascular aneurysm repair (EVAR), the role of anticoagulation therapy on endoleak development and subsequent reintervention is unclear with conflicting data in the literature. The hypothesis of this study is that long-term an
Autor:
Isabel Z, Fernandez, Ryan M, Baxter, Josselyn E, Garcia-Perez, Elena, Vendrame, Thanmayi, Ranganath, Daniel S, Kong, Karl, Lundquist, Tom, Nguyen, Sidney, Ogolla, Jennifer, Black, Csaba, Galambos, James C, Gumbart, Noor, Dawany, Judith R, Kelsen, Edwin F, de Zoeten, Ralph, Quinones, Hesham, Eissa, Michael R, Verneris, Kathleen E, Sullivan, Rosemary, Rochford, Catherine A, Blish, Ross M, Kedl, Cullen M, Dutmer, Elena W Y, Hsieh
Publikováno v:
The Journal of Experimental Medicine
A novel homozygous mutation in human IL2RB results in decreased IL-2Rβ protein expression and dysregulated IL-2/15 signaling. This hypomorphic mutation leads to decreased regulatory T cell frequency and an abnormal NK cell compartment, with clinical
Autor:
Isabel Z, Fernandez, Ryan M, Baxter, Josselyn E, Garcia-Perez, Elena, Vendrame, Thanmayi, Ranganath, Daniel S, Kong, Karl, Lundquist, Tom, Nguyen, Sidney, Ogolla, Jennifer, Black, Csaba, Galambos, James C, Gumbart, Noor, Dawany, Judith R, Kelsen, Edwin F, de Zoeten, Ralph, Quinones, Hesham, Eissa, Michael R, Verneris, Kathleen E, Sullivan, Rosemary, Rochford, Catherine A, Blish, Ross M, Kedl, Cullen M, Dutmer, Elena W Y, Hsieh
Publikováno v:
The Journal of Experimental Medicine
The pleiotropic actions of interleukin-2 (IL-2) are essential for regulation of immune responses and maintenance of immune tolerance. The IL-2 receptor (IL-2R) is composed of IL-2Rα, IL-2Rβ, and IL-2Rγ subunits, with defects in IL-2Rα and IL-2Rγ
Cytokines play a pivotal role in the pathogenesis of autoimmune diseases. Hence, the measurement of cytokine levels has been the focus of multiple studies in an attempt to understand the precise mechanisms that lead to the breakdown of self-tolerance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442c964b5c35649c56b4b322291faadf
https://europepmc.org/articles/PMC6101995/
https://europepmc.org/articles/PMC6101995/