Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Daniel Rupprecht"'
Autor:
Lars Geiger, Volker Bickert, Carsten Schmuck, Uwe Machon, Thomas H. Rehm, Daniel Rupprecht, Michael Merschky, Peter Wich, Jürgen Dudaczek
Publikováno v:
European Journal of Organic Chemistry. 2008:324-329
The synthesis of two versatile building blocks for supramolecular anion binding motifs, 5-(N-Boc-guanidinocarbonyl)-1H-pyrrole-2-carboxylic acid (1) and 5-(N-Cbz-guanidinocarbonyl)-1H-pyrrole-2-carboxylic acid (2) is reported. Using these building bl
Autor:
Daniel Rupprecht, Carsten Schmuck
Publikováno v:
Synthesis. 2007:3095-3110
Pyrrole-containing compounds play an eminent role in nature. Since the development of the pyrrole synthesis by Knorr and Paal at the end of the 19th century, the synthesis and study of modified pyrroles has become an active field of chemical research
Publikováno v:
Chemistry - A European Journal. 12:9186-9195
An artificial dipeptide receptor (1) was designed and observed to bind the deprotonated dipeptide Ac-D-Ala-D-Ala-OH in buffered water with K = 33,100 M(-1), whereas other dipeptides such as Ac-Gly-Gly-OH or Ac-D-Val-D-Val-OH were bound less efficient
Autor:
Markus Schiller, Daniel Rupprecht, Nikolaus Stiefl, Tanja Schirmeister, Ulrich Kaeppler, Carsten Schmuck, Werner Schmitz, John Ziebuhr, Alexander Breuning, Radim Vicik, Knut Baumann
Publikováno v:
Journal of Medicinal Chemistry. 48:6832-6842
The coronavirus main protease, M(pro), is considered to be a major target for drugs suitable for combating coronavirus infections including severe acute respiratory syndrome (SARS). An HPLC-based screening of electrophilic compounds that was performe
Autor:
Carsten Schmuck, Daniel Rupprecht
Publikováno v:
ChemInform. 39
Pyrrole-containing compounds play an eminent role in nature. Since the development of the pyrrole synthesis by Knorr and Paal at the end of the 19th century, the synthesis and study of modified pyrroles has become an active field of chemical research
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 13(24)
Covalent fusion of two artificial recognition motifs for arginine and aspartate resulted in a new class of ditopic RGD receptor molecules, 1-4. The two binding sites for the oppositely charged amino acid residues are linked by either flexible linkers
The large-scale synthesis of three new orthogonally protected pyrrole tricarboxylates 1-3 is described. Using different cleavage conditions, each of the three carboxylates can be set free selectively without affecting theothers, making these pyrrole
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