Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Daniel Reisel"'
Autor:
Thomas E. Bartlett, Iona Evans, Allison Jones, James E. Barrett, Shaun Haran, Daniel Reisel, Kiriaki Papaikonomou, Louise Jones, Chiara Herzog, Nora Pashayan, Bruno M. Simões, Robert B. Clarke, D. Gareth Evans, Talayeh S. Ghezelayagh, Sakthivignesh Ponandai-Srinivasan, Nageswara R. Boggavarapu, Parameswaran G. Lalitkumar, Sacha J. Howell, Rosa Ana Risques, Angelique Flöter Rådestad, Louis Dubeau, Kristina Gemzell-Danielsson, Martin Widschwendter
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Breast cancer is a leading cause of death in premenopausal women. Progesterone drives expansion of luminal progenitor cells, leading to the development of poor-prognostic breast cancers. However, it is not known if antagonising pr
Externí odkaz:
https://doaj.org/article/3c4f667ea36343489d62c2a38deb1ee7
Autor:
James E. Barrett, Allison Jones, Iona Evans, Daniel Reisel, Chiara Herzog, Kantaraja Chindera, Mark Kristiansen, Olivia C. Leavy, Ranjit Manchanda, Line Bjørge, Michal Zikan, David Cibula, Martin Widschwendter
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Most ovarian cancers originate from cells originally derived from Müllerian Duct cells. Here, the authors show that the methylation profile of Müllerian Duct cells isolated from cervical samples can predict whether a woman has cervical cancer.
Externí odkaz:
https://doaj.org/article/6806b9ad19ea44dba63c02d238722b1b
Autor:
James E. Barrett, Chiara Herzog, Allison Jones, Olivia C. Leavy, Iona Evans, Susanne Knapp, Daniel Reisel, Tatiana Nazarenko, Yoo-Na Kim, Dorella Franchi, Andy Ryan, Joanna Franks, Line Bjørge, Michal Zikan, David Cibula, Nadia Harbeck, Nicoletta Colombo, Frank Dudbridge, Louise Jones, Karin Sundström, Joakim Dillner, Angelique Flöter Rådestad, Kristina Gemzell-Danielsson, Nora Pashayan, Martin Widschwendter
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Breast cancer is most commonly diagnosed via a needle biopsy. In this study, the authors show that cervical samples from women with breast cancer have a methylation signature different to that of healthy controls.
Externí odkaz:
https://doaj.org/article/b725d68d5d7e432ebbaed51f8f18f528
Autor:
Thomas E. Bartlett, Iona Evans, Allison Jones, James E. Barrett, Shaun Haran, Daniel Reisel, Kiriaki Papaikonomou, Louise Jones, Chiara Herzog, Nora Pashayan, Bruno M. Simões, Robert B. Clarke, D. Gareth Evans, Talayeh S. Ghezelayagh, Sakthivignesh Ponandai-Srinivasan, Nageswara R. Boggavarapu, Parameswaran G. Lalitkumar, Sacha J. Howell, Rosa Ana Risques, Angelique Flöter Rådestad, Louis Dubeau, Kristina Gemzell-Danielsson, Martin Widschwendter
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/e33dc40c9a65449694cb3d0e780845d4
Autor:
Martin Widschwendter, Iona Evans, Allison Jones, Shohreh Ghazali, Daniel Reisel, Andy Ryan, Aleksandra Gentry-Maharaj, Michal Zikan, David Cibula, Johannes Eichner, Marianna Alunni-Fabbroni, Julian Koch, Wolfgang J. Janni, Tobias Paprotka, Timo Wittenberger, Usha Menon, Benjamin Wahl, Brigitte Rack, Harri Lempiäinen
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-11 (2017)
Abstract Background Monitoring treatment and early detection of fatal breast cancer (BC) remains a major unmet need. Aberrant circulating DNA methylation (DNAme) patterns are likely to provide a highly specific cancer signal. We hypothesized that cel
Externí odkaz:
https://doaj.org/article/3b7fcf15dd4244138f3e3f40fb2fb67b
Autor:
Martin Widschwendter, Michal Zikan, Benjamin Wahl, Harri Lempiäinen, Tobias Paprotka, Iona Evans, Allison Jones, Shohreh Ghazali, Daniel Reisel, Johannes Eichner, Tamas Rujan, Zhen Yang, Andrew E. Teschendorff, Andy Ryan, David Cibula, Usha Menon, Timo Wittenberger
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-14 (2017)
Abstract Background Despite a myriad of attempts in the last three decades to diagnose ovarian cancer (OC) earlier, this clinical aim still remains a significant challenge. Aberrant methylation patterns of linked CpGs analyzed in DNA fragments shed b
Externí odkaz:
https://doaj.org/article/b3b89c9420b64df88de711c291b0cb9e
Autor:
Thomas E. Bartlett, Kantaraja Chindera, Jacqueline McDermott, Charles E. Breeze, William R. Cooke, Allison Jones, Daniel Reisel, Smita T. Karegodar, Rupali Arora, Stephan Beck, Usha Menon, Louis Dubeau, Martin Widschwendter
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Women with germline variants in BRCA genes are predisposed to ovarian cancer. In this study, the authors demonstrate that fimbrial tissue from the ovary, the site of ovarian cancer, in BRCAmutant carriers contains marked DNA methylation changes compa
Externí odkaz:
https://doaj.org/article/c0f2825e826f439a82d6b3c7a397ac25
Autor:
Martin Widschwendter, Matthew Burnell, Lindsay Fraser, Adam N. Rosenthal, Sue Philpott, Daniel Reisel, Louis Dubeau, Mark Cline, Yang Pan, Ping-Cheng Yi, D. Gareth Evans, Ian J. Jacobs, Usha Menon, Charles E. Wood, William C. Dougall
Publikováno v:
EBioMedicine, Vol 2, Iss 10, Pp 1331-1339 (2015)
Breast cancer development in BRCA1/2 mutation carriers is a net consequence of cell-autonomous and cell nonautonomous factors which may serve as excellent targets for cancer prevention. In light of our previous data we sought to investigate the conse
Externí odkaz:
https://doaj.org/article/c1a750bb46dc475e933cb1495b528c24
Autor:
James E. Barrett, Allison Jones, Iona Evans, Chiara Herzog, Daniel Reisel, Adeola Olaitan, Tim Mould, Nicola MacDonald, Konstantinos Doufekas, Claire Newton, Emma J. Crosbie, Line Bjørge, Nicoletta Colombo, Lukas Dostalek, Laura Costas, Paula Peremiquel‐Trillas, Jordi Ponce, Xavier Matias‐Guiu, Michal Zikan, David Cibula, Jiangrong Wang, Karin Sundström, Joakim Dillner, Martin Widschwendter
Publikováno v:
International Journal of Cancer. 152:1977-1988
The incidence of endometrial cancer is rising. Measures to identify women at risk and to detect endometrial cancer earlier are required to reduce the morbidity triggered by the aggressive treatment required for advanced endometrial cancer. We develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53395ae8bc6b03f8ea11232924960bf
https://doi.org/10.1002/ijc.34406
https://doi.org/10.1002/ijc.34406
Autor:
Ranjit Manchanda, Uziel Beller, Ian Tomlinson, Rosa Legood, Huw Dorkins, Chris Jacobs, Usha Menon, Matthew Burnell, Angela F. Brady, Saskia C. Sanderson, Yvonne Wallis, K Loggenberg, Ian Jacobs, Sue Gessler, Lucy Side, Daniel Reisel, R Desai
Publikováno v:
Prevention of gynaecologic cancer.
Introduction/Background* Population-based BRCA-testing in the Ashkenazi Jewish (AJ) population is feasible, acceptable, reduces anxiety, identifies more BRCA-carriers and is cost-effective. The Jewish population is the first population for whom unsel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a09e76b62003c034d111d1007a13d448
https://doi.org/10.1136/ijgc-2021-esgo.557
https://doi.org/10.1136/ijgc-2021-esgo.557