Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel R. Weilandt"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Deciphering the metabolic functions of organisms requires understanding the dynamic responses of living cells upon genetic and environmental perturbations, which in turn can be inferred from enzymatic activity. In this work, we investigate t
Externí odkaz:
https://doaj.org/article/5909942a30c948c684790d4f02463a30
Autor:
Caroline R. Bartman, Daniel R. Weilandt, Yihui Shen, Won Dong Lee, Yujiao Han, Tara TeSlaa, Connor S. R. Jankowski, Laith Samarah, Noel R. Park, Victoria da Silva-Diz, Maya Aleksandrova, Yetis Gultekin, Argit Marishta, Lin Wang, Lifeng Yang, Asael Roichman, Vrushank Bhatt, Taijin Lan, Zhixian Hu, Xi Xing, Wenyun Lu, Shawn Davidson, Martin Wühr, Matthew G. Vander Heiden, Daniel Herranz, Jessie Yanxiang Guo, Yibin Kang, Joshua D. Rabinowitz
Publikováno v:
Nature
Nature, vol 614, iss 7947
Nature, vol 614, iss 7947
Tissues derive ATP from two pathways-glycolysis and the tricarboxylic acid (TCA) cycle coupled to the electrontransport chain. Most energy in mammals is produced via TCA metabolism1. In tumours, however, the absolute rates of these pathways remain un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24537985f0041d48ddf65a08c08ae8e3
https://europepmc.org/articles/PMC10288502/
https://europepmc.org/articles/PMC10288502/
Publikováno v:
Metabolic Engineering
Autor:
Daniel R. Weilandt, Pierre Salvy, Maria Masid, Georgios Fengos, Robin Denhardt-Erikson, Zhaleh Hosseini, Vassily Hatzimanikatis
Publikováno v:
bioRxiv
MotivationLarge-scale kinetic models are an invaluable tool to understand the dynamic and adaptive responses of biological systems. The development and application of these models have been limited by the availability of computational tools to build
Autor:
Louise C. Bryan, Sinan Kilic, Sandrine Georgeon, Oliver Hantschel, Vassily Hatzimanikatis, Beat Fierz, Daniel R. Weilandt, Pascal D. Odermatt, Andreas Bachmann, Carolin C. Lechner, Georg E. Fantner
Publikováno v:
Nucleic Acids Research
Chromatin recruitment of effector proteins involved in gene regulation depends on multivalent interaction with histone post-translational modifications (PTMs) and structural features of the chromatin fiber. Due to the complex interactions involved, i
Publikováno v:
Biophysical Journal
Many computational models for analyzing and predicting cell physiology rely onin vitrodata, collected in dilute and cleanly controlled buffer solutions. However, this can mislead models because about 40% of the intracellular volume is occupied by a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ad2729105a4fd1d36348d9ea2edeb5