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pro vyhledávání: '"Daniel R. Thomases"'
Publikováno v:
J Neurosci
Increased level of kynurenic acid is thought to contribute to the development of cognitive deficits in schizophrenia through an α7nAChR-mediated mechanism in the prefrontal cortex (PFC). However, it remains unclear to what extent disruption of PFC
Publikováno v:
J Neurosci
Understanding how disruption of prefrontal cortex (PFC) maturation during adolescence is crucial to reveal which neural processes could contribute to the onset of psychiatric disorders that display frontal cortical deficits. Of particular interest is
Publikováno v:
Neuropsychopharmacology
The expression of the calcium binding protein parvalbumin (PV) has been observed in several cortical regions during development in a temporal pattern consistent with increased afferent-dependent activity. In the prefrontal cortex (PFC), PV expression
Autor:
María Estela Andrés, Verónica Noches, Marcela González, Francisco Ciruela, Kuei Y. Tseng, Ignacio Vega-Quiroga, Katia Gysling, Daniel R. Thomases, Hector E Yarur
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Neuropsychopharmacology
Universidad de Barcelona
International Journal of Neuropsychopharmacology
Background Basolateral amygdalar projections to the prefrontal cortex play a key role in modulating behavioral responses to stress stimuli. Among the different neuromodulators known to impact basolateral amygdalar-prefrontal cortex transmission, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1db5e6edd8b76420d225840bb4d9960
http://hdl.handle.net/2445/171941
http://hdl.handle.net/2445/171941
Autor:
Ajay Bhandari, John P. Bruno, Robert Schwarcz, Kuei Y. Tseng, Daniel R. Thomases, Daryn K. Cass, Eden Flores-Barrera
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(33)
Increased concentrations of kynurenic acid (KYNA) in the prefrontal cortex (PFC) are thought to contribute to the development of cognitive deficits observed in schizophrenia. Although this view is consistent with preclinical studies showing a negativ
Autor:
Daniel R. Thomases, Kuei Y. Tseng, Li-Jun Heng, Eden Flores-Barrera, Daryn K. Cass, Adriana Caballero
Publikováno v:
Biological Psychiatry. 75:508-516
Background Refinement of mature cognitive functions, such as working memory and decision making, typically takes place during adolescence. The acquisition of these functions is linked to the protracted development of the prefrontal cortex (PFC) and d
Publikováno v:
Biological Psychiatry. 74:490-501
Background Drug experimentation during adolescence is associated with increased risk of drug addiction relative to any other age group. To further understand the neurobiology underlying such liability, we investigate how early adolescent cocaine expe
Publikováno v:
Psychopharmacology. 231:1789-1796
The prefrontal cortex (PFC) receives multiple cortical and subcortical afferents that regulate higher order cognitive functions, many of which emerge late in adolescence. However, it remains unclear how these afferents influence PFC processing, espec
The adolescent susceptibility to the onset of psychiatric disorders is only beginning to be understood when factoring in the development of the prefrontal cortex (PFC). The functional maturation of the PFC is dependent upon proper integration of glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c638af92298cbddbf8f6f4705cd7a6
https://europepmc.org/articles/PMC4078083/
https://europepmc.org/articles/PMC4078083/
Autor:
Kuei Y. Tseng, Eden Flores-Barrera, Daryn K. Cass, Daniel R. Thomases, Adriana Caballero, Webster F. Vital
Publikováno v:
Molecular psychiatry
Converging epidemiological studies indicate that cannabis abuse during adolescence increases the risk of developing psychosis and prefrontal cortex (PFC)-dependent cognitive impairments later in life. However, the mechanisms underlying the adolescent